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Giant unilamellar vesicles (GUVs), are a convenient tool to study membrane-bound processes using optical microscopy. An increasing number of studies highlights the potential of these model membranes when addressing questions in membrane…

Biomolecules · Quantitative Biology 2018-06-27 Roland L. Knorr , Jan Steinkuehler , Rumiana Dimova

Membrane organization is essential for cellular functions such as signal transduction and membrane trafficking. A major challenge is to understand the lateral heterogeneous structures in membranes and membrane fluidity in the presence of…

Soft Condensed Matter · Physics 2007-11-09 Chun-Lai Ren , Yu-qiang Ma

Continuum elastic models that account for membrane thickness variations are especially useful in the description of nanoscale deformations due to the presence of membrane proteins with hydrophobic mismatch. We show that terms involving the…

Soft Condensed Matter · Physics 2012-11-12 Anne-Florence Bitbol , Doru Constantin , Jean-Baptiste Fournier

This communication reports the surface pressure vs. area per molecule isotherm and Fluorescence Imaging Microscopic studies of the formation of domain structure in the mixed Langmuir monolayer of RhB and Stearic acid (SA) at the air water…

Materials Science · Physics 2011-06-21 S. A. Hussain , S. Chakraborty , D. Bhattacharjee

The domain formation of curvature-inducing molecules, such as peripheral or transmembrane proteins and conical surfactants, is studied in thermal equilibrium and nonequilibrium steady states using meshless membrane simulations. These…

Soft Condensed Matter · Physics 2023-01-30 Hiroshi Noguchi

Simulation of a multicomponent lipid bilayer having a fixed percentage of cholesterol is done to study phase transition leading to domain formation. The concept of random lattice has been used in simulation to account for the coupling…

Soft Condensed Matter · Physics 2015-06-25 Srilekha Banerjee , Jayashree Saha

Liquids in contact with solids are submitted to intermolecular forces making liquids heterogeneous and stress tensors are not any more spherical as in homogeneous bulks. The aim of this article is to show that a square-gradient functional…

Classical Physics · Physics 2017-08-23 Henri Gouin

We present Monte Carlo simulations of an ultra coarse-grained lipid bilayer with different number of lipids on both leaflets. In the simulations, we employ a new method for measuring the elastic parameters of the membrane, including the…

Soft Condensed Matter · Physics 2025-05-20 Oded Farago

Response of lipid bilayers to external mechanical stimuli is an active area of research with implications for fundamental and synthetic cell biology. However, there is a lack of tools for systematically imposing mechanical strains and…

Motivated by recent experimental work on multicomponent lipid membranes supported by colloidal scaffolds, we report an exhaustive theoretical investigation of the equilibrium configurations of binary mixtures on curved substrates. Starting…

Soft Condensed Matter · Physics 2018-09-12 Piermarco Fonda , Melissa Rinaldin , Daniela J. Kraft , Luca Giomi

Biomolecules exhibit dynamic conformations critical to their functions, yet observing these processes at the single-molecule level under native conditions remains a formidable challenge. While surface immobilization has been widely used to…

Instrumentation and Detectors · Physics 2025-12-22 Funing Liu , Qitao Hu , Anton Sabantsev , Giovanni Di Muccio , Shuangshuang Zeng , Mauro Chinappi , Sebastian Deindl , Zhen Zhang

Membrane proteins serve a wide range of vital roles in the functioning of living organisms. Compared to other classes of proteins, determining membrane protein structures remains a challenge, in large part due to the difficulty in…

Liposomes that achieve a heterogeneous and spatially organized surface through phase separation have been recognized to be a promising platform for delivery purposes. However, their design and optimization through experimentation can be…

Soft Condensed Matter · Physics 2021-11-05 Y. Wang , Y. Palzhanov , A. Quaini , M. Olshanskii , S. Majd

Whereas many studies have examined stabilization of emulsions and foams in low salinity aqueous phases with nanoparticles (NPs) with and without added surfactants, interest has grown recently in much higher salinities relevant to subsurface…

X-ray nanodiffraction is applied to study the formation and correlation of domain boundaries in mesocrystalline superlattices of PbS nanocrystals with face-centered cubic structure. Each domain of the superlattice can be described with one…

Surface nanobubbles are nanoscopic spherical-cap shaped gaseous domains on immersed substrates which are stable, even for days. After the stability of a {\it single} surface nanobubble has been theoretically explained, i.e. contact line…

Fluid Dynamics · Physics 2020-02-06 Xiaojue Zhu , Roberto Verzicco , Xuehua Zhang , Detlef Lohse

Multivalent interactions between deformable mesoscopic units are ubiquitous in biology, where membrane macromolecules mediate the interactions between neighbouring living cells and between cells and solid substrates. Lately, analogous…

Biological Physics · Physics 2015-04-20 S. F. Shimobayashi , B. M. Mognetti , L. Parolini , D. Orsi , P. Cicuta , L. Di Michele

Nanoscale ferroelectric topologies such as vortices, anti-vortices, bubble patterns etc. are stabilized in thin films by a delicate balance of both mechanical and electrical boundary conditions. A systematic understanding of the phase…

Recent research has revealed several different techniques for nanoscopic gas nucleation on submerged surfaces, with findings seemingly in contradiction with each other. In response to this, we have systematically investigated the occurrence…

This study utilizes molecular dynamics simulations to scrutinize the influence of type and volume fraction of nanoparticle on the density of nanofluids, i.e. silver (as a hydrophilic case) and titanium dioxide (as a hydrophobic case)…

Applied Physics · Physics 2021-05-20 M. M. Heyhat , M. Abbasi , A. Rajabpour