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Background: Effective use of mobile health technologies requires high participant adherence and retention. However, remote digital health studies often face high attrition and low adherence, potentially introducing bias and limiting…

Quantitative Methods · Quantitative Biology 2025-09-29 Dylan Hamitouche , Youcef Barkat , Deven Parekh , Eva Hammer , David Benrimoh

People with diabetes are at risk of developing an eye disease called diabetic retinopathy (DR). This disease occurs when high blood glucose levels cause damage to blood vessels in the retina. Computer-aided DR diagnosis is a promising tool…

Computer Vision and Pattern Recognition · Computer Science 2020-11-12 Yi Zhou , Boyang Wang , Lei Huang , Shanshan Cui , Ling Shao

Diabetic Retinopathy (DR), a leading cause of vision impairment in individuals with diabetes, affects approximately 34.6% of diabetes patients globally, with the number of cases projected to reach 242 million by 2045. Traditional DR…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Akwasi Asare , Dennis Agyemanh Nana Gookyi , Derrick Boateng , Fortunatus Aabangbio Wulnye

Prediction uncertainty estimation has clinical significance as it can potentially quantify prediction reliability. Clinicians may trust 'blackbox' models more if robust reliability information is available, which may lead to more models…

Machine Learning · Computer Science 2022-10-04 Michael Dohopolski , Kai Wang , Biling Wang , Ti Bai , Dan Nguyen , David Sher , Steve Jiang , Jing Wang

Current clinical decision support systems (DSS) are trained and validated on observational data from the target clinic. This is problematic for treatments validated in a randomized clinical trial (RCT), but not yet introduced in any clinic.…

Background: Type 2 diabetes (T2D) is a prevalent chronic disease with a significant risk of serious health complications and negative impacts on the quality of life. Given the impact of individual characteristics and lifestyle on the…

Machine Learning · Computer Science 2024-01-08 Syed Hasib Akhter Faruqui , Adel Alaeddini , Yan Du , Shiyu Li , Kumar Sharma , Jing Wang

Opaque algorithms disseminate and mediate the content that users consume on online social media platforms. This algorithmic mediation serves users with contents of their liking, on the other hand, it may cause several inadvertent risks to…

Social and Information Networks · Computer Science 2025-01-28 Cai Yang , Sepehr Mousavi , Abhisek Dash , Krishna P. Gummadi , Ingmar Weber

Machine learning techniques combined with in-home monitoring technologies provide a unique opportunity to automate diagnosis and early detection of adverse health conditions in long-term conditions such as dementia. However, accessing…

In many nations, diabetes is becoming a significant health problem, and early identification and control are crucial. Using machine learning algorithms to predict diabetes has yielded encouraging results. Using the Pima Indians Diabetes…

Machine Learning · Computer Science 2025-06-13 Mowafaq Salem Alzboon , Mohammad Al-Batah , Muhyeeddin Alqaraleh , Ahmad Abuashour , Ahmad Fuad Bader

The task of predicting long-term patient outcomes using supervised machine learning is a challenging one, in part because of the high variance of each patient's trajectory, which can result in the model over-fitting to the training data.…

Machine Learning · Computer Science 2026-02-09 Thomas Frost , Kezhi Li , Steve Harris

Machine learning has been an emerging tool for various aspects of infectious diseases including tuberculosis surveillance and detection. However, WHO provided no recommendations on using computer-aided tuberculosis detection software…

Computer Vision and Pattern Recognition · Computer Science 2020-08-04 Seelwan Sathitratanacheewin , Krit Pongpirul

Identifying preclinical biomarkers of neurodegenerative diseases remains a major challenge in aging research. In this study, we demonstrate that frequent "Don't know/can't remember" (DK) responses, often treated as missing data in…

Applications · Statistics 2025-12-16 Yukun Lu , Bingjie Li , Zhigang Yao

Cancer remains a leading cause of death worldwide, necessitating personalized treatment approaches to improve outcomes. Theranostics, combining molecular-level imaging with targeted therapy, offers potential for precision oncology but…

Computational Engineering, Finance, and Science · Computer Science 2025-05-16 Binesh Sadanandan , Vahid Behzadan

Diabetic Retinopathy (DR), a vision-threatening complication of Dia-betes Mellitus (DM), is a major global concern, particularly in India, which has one of the highest diabetic populations. Prolonged hyperglycemia damages reti-nal…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Arpan Maity , Aviroop Pal , MD. Samiul Islam , Tamal Ghosh

This paper proposes applying a novel deep-learning model, TBDLNet, to recognize CT images to classify multidrug-resistant and drug-sensitive tuberculosis automatically. The pre-trained ResNet50 is selected to extract features. Three…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Ziquan Zhu , Jing Tao , Shuihua Wang , Xin Zhang , Yudong Zhang

Poor medication adherence presents serious economic and health problems including compromised treatment effectiveness, medical complications, and loss of billions of dollars in wasted medicine or procedures. Though various interventions…

Artificial Intelligence · Computer Science 2021-05-20 Chrisogonas Odhiambo , Pamela Wright , Cindy Corbett , Homayoun Valafar

Tuberculosis (TB) is a contagious disease that causes 1.5 million deaths per year globally. Early diagnosis of TB patients is critical to control its spread. However, standard TB diagnostic tests such as sputum culture take days to weeks to…

Medical Physics · Physics 2022-08-26 Ubaid Ullah , Zarfishan Tahir , Obaidullah Qazi , Shaper Mirza , M. Imran Cheema

Online adaptive radiotherapy (ART) requires accurate and efficient auto-segmentation of target volumes and organs-at-risk (OARs) in mostly cone-beam computed tomography (CBCT) images. Propagating expert-drawn contours from the pre-treatment…

Computer Vision and Pattern Recognition · Computer Science 2023-05-10 Xiao Liang , Jaehee Chun , Howard Morgan , Ti Bai , Dan Nguyen , Justin C. Park , Steve Jiang

In this paper we investigate the use of model-based reinforcement learning to assist people with Type 1 Diabetes with insulin dose decisions. The proposed architecture consists of multiple Echo State Networks to predict blood glucose levels…

Repetitive laboratory testing unlikely to yield clinically useful information is a common practice that burdens patients and increases healthcare costs. Education and feedback interventions have limited success, while general test ordering…