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Diffusion Posterior Sampling(DPS) methodology is a novel framework that permits nonlinear CT reconstruction by integrating a diffusion prior and an analytic physical system model, allowing for one-time training for different applications.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Xiao Jiang , Shudong Li , Peiqing Teng , Grace Gang , J. Webster Stayman

Purpose: Apparent diffusion coefficient (ADC) maps derived from diffusion weighted (DWI) MRI provides functional measurements about the water molecules in tissues. However, DWI is time consuming and very susceptible to image artifacts,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Zach Eidex , Mojtaba Safari , Jacob Wynne , Richard L. J. Qiu , Tonghe Wang , David Viar Hernandez , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Deep learning has a great potential for estimating biomarkers in diffusion weighted magnetic resonance imaging (dMRI). Atlases, on the other hand, are a unique tool for modeling the spatio-temporal variability of biomarkers. In this paper,…

Medical Physics · Physics 2022-05-09 Davood Karimi , Ali Gholipour

Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Bo Li , Marius de Groot , Rebecca M. E. Steketee , Rozanna Meijboom , Marion Smits , Meike W. Vernooij , M. Arfan Ikram , Jiren Liu , Wiro J. Niessen , Esther E. Bron

Deep learning methods for accelerated MRI achieve state-of-the-art results but largely ignore additional speedups possible with noncartesian sampling trajectories. To address this gap, we created a generative diffusion model-based…

Artificial Intelligence · Computer Science 2024-10-02 Trevor J. Chan , Chamith S. Rajapakse

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

Magnetic resonance imaging (MRI) is a potent diagnostic tool, but suffers from long examination times. To accelerate the process, modern MRI machines typically utilize multiple coils that acquire sub-sampled data in parallel. Data-driven…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Moritz Erlacher , Martin Zach

Magnetic resonance imaging (MRI) is mainly limited by long scanning time and vulnerable to human tissue motion artifacts, in 3D clinical scenarios. Thus, k-space undersampling is used to accelerate the acquisition of MRI while leading to…

Image and Video Processing · Electrical Eng. & Systems 2022-01-11 Shengke Xue , Ruiliang Bai , Xinyu Jin

Functional connectivity estimates are highly sensitive to analysis choices and can be dominated by noise when the number of sampled time points is small relative to network dimensionality. This issue is particularly acute in fMRI, where…

Disordered Systems and Neural Networks · Physics 2026-02-10 Izaro Fernandez-Iriondo , Antonio Jimenez-Marin , Jesus Cortes , Pablo Villegas

Magnetic Resonance Imaging (MRI) is a powerful, non-invasive diagnostic tool; however, its clinical applicability is constrained by prolonged acquisition times. Whilst present deep learning-based approaches have demonstrated potential in…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Anurag Malyala , Zhenlin Zhang , Chengyan Wang , Chen Qin

This paper introduces a new unsupervised method for dimensionality reduction via regression (DRR). The algorithm belongs to the family of invertible transforms that generalize Principal Component Analysis (PCA) by using curvilinear instead…

Machine Learning · Statistics 2016-02-02 Valero Laparra , Jesus Malo , Gustau Camps-Valls

Purpose: To accelerate MRI acquisition by incorporating the previous scans of a subject during reconstruction. Although longitudinal imaging constitutes much of clinical MRI, leveraging previous scans is challenging due to the complex…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Yonatan Urman , Zachary Shah , Ashwin Kumar , Bruno P. Soares , Kawin Setsompop

Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Xiaoyi Wen , Fei Jiang

The study of brain differences across Eastern and Western populations provides vital insights for understanding potential cultural and genetic influences on cognition and mental health. Diffusion MRI (dMRI) tractography is an important tool…

Diffusion MRI (dMRI) streamline tractography, the gold standard for in vivo estimation of brain white matter (WM) pathways, has long been considered indicative of macroscopic relationships with WM microstructure. However, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Tian Yu , Yunhe Li , Michael E. Kim , Chenyu Gao , Qi Yang , Leon Y. Cai , Susane M. Resnick , Lori L. Beason-Held , Daniel C. Moyer , Kurt G. Schilling , Bennett A. Landman

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang

Purpose: To propose a deep learning-based reconstruction framework for ultrafast and robust diffusion tensor imaging and fiber tractography. Methods: We propose SuperDTI to learn the nonlinear relationship between diffusion-weighted images…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Hongyu Li , Zifei Liang , Chaoyi Zhang , Ruiying Liu , Jing Li , Weihong Zhang , Dong Liang , Bowen Shen , Xiaoliang Zhang , Yulin Ge , Jiangyang Zhang , Leslie Ying

Magnetic Resonance Imaging (MRI) produces excellent soft tissue contrast, albeit it is an inherently slow imaging modality. Promising deep learning methods have recently been proposed to reconstruct accelerated MRI scans. However, existing…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Yilmaz Korkmaz , Tolga Cukur , Vishal M. Patel

Magnetic resonance imaging (MRI) is a powerful medical imaging modality, but long acquisition times limit throughput, patient comfort, and clinical accessibility. Diffusion-based generative models serve as strong image priors for reducing…

Machine Learning · Computer Science 2026-02-13 Sriram Ravula , Brett Levac , Yamin Arefeen , Ajil Jalal , Alexandros G. Dimakis , Jonathan I. Tamir

Diffusion tensor imaging (DTI) provides crucial insights into the microstructure of the human brain, but it can be time-consuming to acquire compared to more readily available T1-weighted (T1w) magnetic resonance imaging (MRI). To address…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shaorong Zhang , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Jose-Luis Ambite , Paul M. Thompson , Greg Ver Steeg
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