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The optimal selection of experimental conditions is essential to maximizing the value of data for inference and prediction, particularly in situations where experiments are time-consuming and expensive to conduct. We propose a general…

Machine Learning · Statistics 2012-12-04 Xun Huan , Youssef M. Marzouk

Many public health interventions are conducted in settings where individuals are connected to one another and the intervention assigned to randomly selected individuals may spill over to other individuals they are connected to. In these…

Methodology · Statistics 2026-01-14 Junhan Fang , Donna Spiegelman , Ashley Buchanan , Laura Forastiere

The neural network is a powerful computing framework that has been exploited by biological evolution and by humans for solving diverse problems. Although the computational capabilities of neural networks are determined by their structure,…

Neural and Evolutionary Computing · Computer Science 2019-03-27 Nathaniel Rodriguez , Eduardo Izquierdo , Yong-Yeol Ahn

The network inference problem arises in biological research when one needs to quantitatively choose the best protein-interaction model for explaining a phenotype. The diverse nature of the data and nonlinear dynamics pose significant…

Molecular Networks · Quantitative Biology 2025-12-22 Guy Karlebach

Robust optimization is concerned with constructing solutions that remain feasible also when a limited number of resources is removed from the solution. Most studies of robust combinatorial optimization to date made the assumption that every…

Optimization and Control · Mathematics 2015-04-21 David Adjiashvili

The stochastic block model (SBM) is a mixture model used for the clustering of nodes in networks. It has now been employed for more than a decade to analyze very different types of networks in many scientific fields such as Biology and…

Methodology · Statistics 2014-05-12 E. Côme , P. Latouche

To identify the robust settings of the control factors, it is very important to understand how they interact with the noise factors. In this article, we propose space-filling designs for computer experiments that are more capable of…

Methodology · Statistics 2018-11-26 V. Roshan Joseph , Li Gu , Shan Ba , William R. Myers

The stochastic block model (SBM) is a flexible probabilistic tool that can be used to model interactions between clusters of nodes in a network. However, it does not account for interactions of time varying intensity between clusters. The…

Machine Learning · Statistics 2017-07-11 Marco Corneli , Pierre Latouche , Fabrice Rossi

Modularity has been widely studied as a mechanism to improve the capabilities of neural networks through various techniques such as hand-crafted modular architectures and automatic approaches. While these methods have sometimes shown…

Neural and Evolutionary Computing · Computer Science 2024-10-28 Humphrey Munn , Marcus Gallagher

Mixture models are probabilistic models aimed at uncovering and representing latent subgroups within a population. In the realm of network data analysis, the latent subgroups of nodes are typically identified by their connectivity…

Methodology · Statistics 2020-05-27 Giacomo De Nicola , Benjamin Sischka , Göran Kauermann

Network's resilience to the malfunction of its components has been of great concern. The goal of this work is to determine the network design guidelines, which maximizes the network efficiency while keeping the cost of the network (that is…

Disordered Systems and Neural Networks · Physics 2009-11-11 Bing Wang , Huanwen Tang , Chonghui Guo , Zhilong Xiu , Tao Zhou

In this paper, we propose an optimization framework to design a network of positive linear systems whose structure switches according to a Markov process. The optimization framework herein proposed allows the network designer to optimize…

Optimization and Control · Mathematics 2019-03-19 Masaki Ogura , Victor M. Preciado

Motivated by multi-subject experiments in neuroimaging studies, we develop a modeling framework for joint community detection in a group of related networks, which can be considered as a sample from a population of networks. The proposed…

Applications · Statistics 2020-03-24 Subhadeep Paul , Yuguo Chen

Community structure in networks is observed in many different domains, and unsupervised community detection has received a lot of attention in the literature. Increasingly the focus of network analysis is shifting towards using network…

Methodology · Statistics 2020-03-02 Jesús Arroyo , Elizaveta Levina

Modeling relations between individuals is a classical question in social sciences and clustering individuals according to the observed patterns of interactions allows to uncover a latent structure in the data. Stochastic block model (SBM)…

Methodology · Statistics 2015-01-27 Pierre Barbillon , Sophie Donnet , Emmanuel Lazega , Avner Bar-Hen

Many interventions, such as vaccines in clinical trials or coupons in online marketplaces, must be assigned sequentially without full knowledge of their effects. Multi-armed bandit algorithms have proven successful in such settings.…

Machine Learning · Statistics 2026-05-07 Aidan Gleich , Eric Laber , Alexander Volfovsky

For biological experiments aiming at calibrating models with unknown parameters, a good experimental design is crucial, especially for those subject to various constraints, such as financial limitations, time consumption and physical…

Applications · Statistics 2014-07-22 Xiao Lin , Gabriel Terejanu

We propose a computational approach to constructing exact designs on finite design spaces that are optimal for multiresponse regression experiments under a combination of the standard linear and specific 'sparsity' constraints. The linear…

Methodology · Statistics 2026-02-13 Lenka Filová , Pál Somogyi , Radoslav Harman

We construct optimal designs for group testing experiments where the goal is to estimate the prevalence of a trait by using a test with uncertain sensitivity and specificity. Using optimal design theory for approximate designs, we show that…

Statistics Theory · Mathematics 2017-01-05 Shih-Hao Huang , Mong-Na Lo Huang , Kerby Shedden , Weng Kee Wong

How should a network experiment be designed to achieve high statistical power? Ex- perimental treatments on networks may spread. Randomizing assignment of treatment to nodes enhances learning about the counterfactual causal effects of a…

Methodology · Statistics 2018-04-02 Jake Bowers , Bruce A. Desmarais , Mark Frederickson , Nahomi Ichino , Hsuan-Wei Lee , Simi Wang
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