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We present a machine learning approach to calculating electronic specific heat capacities for a variety of benchmark molecular systems. Our models are based on data from density matrix quantum Monte Carlo, which is a stochastic method that…

We apply three machine learning strategies to optimize the atomic cooling processes utilized in the production of a Bose-Einstein condensate (BEC). For the first time, we optimize both laser cooling and evaporative cooling mechanisms…

Entropy production (EP) is a key quantity in thermodynamics, and yet measuring EP has remained a challenging task. Here we introduce an EP estimator, called multidimensional entropic bound (MEB), utilizing an ensemble of trajectories…

Statistical Mechanics · Physics 2024-09-06 Sangyun Lee , Dong-Kyum Kim , Jong-Min Park , Won Kyu Kim , Hyunggyu Park , Jae Sung Lee

Hyperparameter tuning is a challenging problem especially when the system itself involves uncertainty. Due to noisy function evaluations, optimization under uncertainty can be computationally expensive. In this paper, we present a novel…

Machine Learning · Computer Science 2025-10-09 Akash Yadav , Ruda Zhang

Measurement error mitigation (MEM) techniques are postprocessing strategies to counteract systematic read-out errors on quantum computers (QC). Currently used MEM strategies face a tradeoff: methods that scale well with the number of qubits…

Quantum Physics · Physics 2022-10-25 Siddarth Srinivasan , Bibek Pokharel , Gregory Quiroz , Byron Boots

A parameterization strategy for molecular models on the basis of force fields is proposed, which allows a rapid development of models for small molecules by using results from quantum mechanical (QM) ab initio calculations and thermodynamic…

Chemical Physics · Physics 2009-04-22 Bernhard Eckl , Jadran Vrabec , Hans Hasse

Identifying dynamical system (DS) is a vital task in science and engineering. Traditional methods require numerous calls to the DS solver, rendering likelihood-based or least-squares inference frameworks impractical. For efficient parameter…

Computation · Statistics 2024-09-19 Ying Zhou , Jinglai Li , Xiang Zhou , Hongqiao Wang

Calculating thermodynamic potentials and observables efficiently and accurately is key for the application of statistical mechanics simulations to materials science. However, naive Monte Carlo approaches, on which such calculations are…

Statistical Mechanics · Physics 2021-07-15 James Damewood , Daniel Schwalbe-Koda , Rafael Gomez-Bombarelli

We develop a spatio-temporal model to forecast sensor output at five locations in North East England. The signal is described using coupled dynamic linear models, with spatial effects specified by a Gaussian process. Data streams are…

Applications · Statistics 2018-06-15 Yingying Lai , Andrew Golightly , Richard Boys

Identifying and calibrating quantitative dynamical models for physical quantum systems is important for a variety of applications. Here we present a closed-loop Bayesian learning algorithm for estimating multiple unknown parameters in a…

Quantum phase estimation (QPE) is the key subroutine of several quantum computing algorithms as well as a central ingredient in quantum computational chemistry and quantum simulation. While QPE strategies have focused on the estimation of a…

Quantum Physics · Physics 2021-07-26 Valentin Gebhart , Augusto Smerzi , Luca Pezzè

Early event prediction (EEP) systems continuously estimate a patient's imminent risk to support clinical decision-making. For bedside trust, risk trajectories must be accurate and temporally stable, shifting only with new, relevant…

Machine Learning · Computer Science 2025-10-17 Mayank Keoliya , Seewon Choi , Rajeev Alur , Mayur Naik , Eric Wong

This study employed an artificial intelligence-enhanced molecular simulation framework to enable efficient Path Integral Molecular Dynamics (PIMD) simulations. Owing to its modular architecture and high-throughput capabilities, the…

Chemical Physics · Physics 2025-04-01 Cheng Fan , Maodong Li , Sihao Yuan , Zhaoxin Xie , Dechin Chen , Yi Isaac Yang , Yi Qin Gao

The quality of training data is critical to the performance of machine learning models. In this paper, the Error Sensitivity Profile (ESP) is proposed. It quantifies the sensitivity of model performance to errors in a single feature or in…

Machine Learning · Computer Science 2026-04-29 Andrea Maurino

This study presents a comprehensive framework for uncertainty quantification (UQ) and design optimization of plasma etching in semiconductor manufacturing. The framework is demonstrated using experimental measurements of etched depth…

Popular Physics · Physics 2025-11-10 Yongsu Jung , Minji Kang , Muyoung Kim , Min Sup Choi , Hyeong-U Kim , Jaekwang Kim

Accurately predicting protein-ligand binding free energies (BFEs) remains a central challenge in drug discovery, particularly because the most reliable methods, such as free energy perturbation (FEP), are computationally intensive and…

Chemical Physics · Physics 2025-12-09 Farzad Molani , Art E. Cho

Large-scale applications of energy density functional (EDF) methods depend on fast and reliable algorithms to solve the associated non-linear self-consistency problem. When dealing with large single-particle variational spaces, existing…

Nuclear Theory · Physics 2019-06-24 W. Ryssens , M. Bender , P. -H. Heenen

Accurate computation of non-covalent, intermolecular interaction energies is important to understand various chemical phenomena, and quantum computers are anticipated to accelerate it. Although the state-of-the-art quantum computers are…

Quantum Physics · Physics 2025-12-29 Yuhei Tachi , Akihiko Arakawa , Taisei Osawa , Masayoshi Terabe , Kenji Sugisaki

Understanding the dynamic properties of the uniform electron gas (UEG) is important for numerous applications ranging from semiconductor physics to exotic warm dense matter. In this work, we apply the maximum entropy method (MEM), as…

Strongly Correlated Electrons · Physics 2025-09-19 Thomas Chuna , Nicholas Barnfield , Jan Vorberger , Michael P. Friedlander , Tim Hoheisel , Tobias Dornheim

The minimum error entropy (MEE) has been extensively used in unscented Kalman filter (UKF) to handle impulsive noises or abnormal measurement data in non-Gaussian systems. However, the MEE-UKF has poor numerical stability due to the inverse…

Signal Processing · Electrical Eng. & Systems 2023-09-19 Boyu Tian , Haiquan Zhao
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