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Biological networks provide insight into the complex organization of biological processes in a cell at the system level. They are an effective tool for understanding the comprehensive map of functional interactions, finding the functional…

Molecular Networks · Quantitative Biology 2017-09-14 Somaye Hashemifar

The human organism is an integrated network where complex physiologic systems, each with its own regulatory mechanisms, continuously interact, and where failure of one system can trigger a breakdown of the entire network. Identifying and…

Data Analysis, Statistics and Probability · Physics 2012-03-02 Amir Bashan , Ronny P. Bartsch , Jan W. Kantelhardt , Shlomo Havlin , Plamen Ch. Ivanov

Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

Neurons and Cognition · Quantitative Biology 2024-02-28 Jiachen Yao , Nina Hagemann , Qiaojie Xiong , Jianxu Chen , Dirk M. Hermann , Chao Chen

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

The irreducible complexity of natural phenomena has led Graph Neural Networks to be employed as a standard model to perform representation learning tasks on graph-structured data. While their capacity to capture local and global patterns is…

Machine Learning · Computer Science 2024-02-13 Lorenzo Giusti

The relationship between the regulatory design and the functionality of molecular networks is a key issue in biology. Modules and motifs have been associated to various cellular processes, thereby providing anecdotal evidence for…

Molecular Networks · Quantitative Biology 2008-03-04 Jacob Bock Axelsen , Sebastian Bernhardsson , Kim Sneppen

The human brain cortical layer has a convoluted morphology that is unique to each individual. Characterization of the cortical morphology is necessary in longitudinal studies of structural brain change, as well as in discriminating…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Sevil Maghsadhagh , Mousa Shamsi , Anders Eklund , Hamid Behjat

Recent studies have pointed out the importance of transient synchronization between widely distributed neural assemblies to understand conscious perception. These neural assemblies form intricate networks of neurons and synapses whose…

Neurons and Cognition · Quantitative Biology 2010-11-09 Jesus Gomez-Gardenes , Gorka Zamora-Lopez , Yamir Moreno , Alex Arenas

A great variety of systems in nature, society and technology -- from the web of sexual contacts to the Internet, from the nervous system to power grids -- can be modeled as graphs of vertices coupled by edges. The network structure,…

Adaptation and Self-Organizing Systems · Physics 2012-10-10 Petter Holme , Jari Saramäki

Neural networks modularity is a major challenge for the development of control circuits of neural activity. Under physiological limitations, the accessible regions for external stimulation are possibly different from the functionally…

Neurons and Cognition · Quantitative Biology 2018-02-23 Hanna Keren , Johannes Partzsch , Shimon Marom , Christian Mayr

The large-scale structural ingredients of the brain and neural connectomes have been identified in recent years. These are, similar to the features found in many other real networks: the arrangement of brain regions into modules and the…

Neurons and Cognition · Quantitative Biology 2018-11-01 Gorka Zamora-López , Yuhan Chen , Gustavo Deco , Morten L. Kringelbach , Changsong Zhou

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

Neural and Evolutionary Computing · Computer Science 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

The behavior of many complex systems is determined by a core of densely interconnected units. While many methods are available to identify the core of a network when connections between nodes are all of the same type, a principled approach…

Neurons and Cognition · Quantitative Biology 2018-09-14 Federico Battiston , Jeremy Guillon , Mario Chavez , Vito Latora , Fabrizio De Vico Fallani

Most studies indicate that intelligence (g) is positively correlated with cortical thickness. However, the interindividual variability of cortical thickness has not been taken into account. In this study, we aimed to identify the…

Neurons and Cognition · Quantitative Biology 2019-11-25 Qi Zhao , Lingli Zhang , Chun Shen , Jie Zhang , Jianfeng Feng

Exploring the structural topology of genome-based large-scale metabolic network is essential for investigating possible relations between structure and functionality. Visualization would be helpful for obtaining immediate information about…

Molecular Networks · Quantitative Biology 2007-09-06 Zhao Jing , Tao Lin , Yu Hong , Luo Jian-Hua , Z. W. Cao , Li Yixue

Spatially or chemically isolated functional modules composed of several cellular components and carrying discrete functions are considered fundamental building blocks of cellular organization, but their presence in highly integrated…

Soft Condensed Matter · Physics 2009-11-07 E. Ravasz , A. L. Somera , D. A. Mongru , Z. N. Oltvai , A. -L. Barabasi

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Correlated electrical activity in neurons is a prominent characteristic of cortical microcircuits. Despite a growing amount of evidence concerning both spike-count and subthreshold membrane potential pairwise correlations, little is known…

Neurons and Cognition · Quantitative Biology 2019-07-29 Daniele Linaro , Gabriel K. Ocker , Brent Doiron , Michele Giugliano

Studying the cellular architecture of the human cerebral cortex is critical for understanding brain organization and function. It requires investigating complex texture patterns in histological images, yet automatic methods that scale…

Neurons and Cognition · Quantitative Biology 2026-03-06 Christian Schiffer , Zeynep Boztoprak , Jan-Oliver Kropp , Julia Thönnißen , Katia Berr , Hannah Spitzer , Katrin Amunts , Timo Dickscheid