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Medical imaging phantoms are widely used for validation and verification of imaging systems and algorithms in surgical guidance and radiation oncology procedures. Especially, for the performance evaluation of new algorithms in the field of…

3D printing has been widely adopted for clinical decision making and interventional planning of Congenital heart disease (CHD), while whole heart and great vessel segmentation is the most significant but time-consuming step in the model…

Image and Video Processing · Electrical Eng. & Systems 2019-07-15 Xiaowei Xu , Tianchen Wang , Dewen Zeng , Yiyu Shi , Qianjun Jia , Haiyun Yuan , Meiping Huang , Jian Zhuang

Purpose: Anthropomorphic phantoms can be used in radiotherapy to confirm dose distributions. In this work, a prototype phantom with a deformable chest wall was created based on real human. Methods: A technique similar to 3-dimensional…

Medical Physics · Physics 2021-11-11 Maria Akiki , Fadi Rouphael , Mazen Moussallem

Myocardial infarction (MI) is one of the most prevalent cardiovascular diseases with associated clinical decision-making typically based on single-valued imaging biomarkers. However, such metrics only approximate the complex 3D structure…

Computer Vision and Pattern Recognition · Computer Science 2023-07-17 Marcel Beetz , Yilong Yang , Abhirup Banerjee , Lei Li , Vicente Grau

Knowledge of appropriate local fiber architecture is necessary to simulate patient-specific electromechanics in the human heart. However, it is not yet possible to reliably measure in-vivo fiber directions, especially in human atria. Thus,…

The AstroMed project at Harvard University's Initiative in Innovative Computing (IIC) is working on improved visualization and data sharing solutions applicable to the fields of both astronomy and medicine. The current focus is on the…

Astrophysics · Physics 2007-05-23 Michelle Borkin , Alyssa Goodman , Michael Halle , Douglas Alan

Electroanatomical mapping is a technique used in cardiology to create a detailed 3D map of the electrical activity in the heart. It is useful for diagnosis, treatment planning and real time guidance in cardiac ablation procedures to treat…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Sunil Mathew , Jasbir Sra , Daniel B. Rowe

Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Fanwei Kong , Aaron Brown , Michael Loecher , Perry S. Choi , Lei Shi , Michael Ma , Daniel B. Ennis , Alison Marsden

Cardiac segmentation of atriums, ventricles, and myocardium in computed tomography (CT) images is an important first-line task for presymptomatic cardiovascular disease diagnosis. In several recent studies, deep learning models have shown…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Sanguk Park , Minyoung Chung

Alterations in the geometry and function of the heart define well-established causes of cardiovascular disease. However, current approaches to the diagnosis of cardiovascular diseases often rely on subjective human assessment as well as…

Computer Vision and Pattern Recognition · Computer Science 2018-07-19 Carlo Biffi , Ozan Oktay , Giacomo Tarroni , Wenjia Bai , Antonio De Marvao , Georgia Doumou , Martin Rajchl , Reem Bedair , Sanjay Prasad , Stuart Cook , Declan O'Regan , Daniel Rueckert

We present the first geometric deep learning framework based on point cloud representation for 3D four-chamber cardiac reconstruction from cine MRI data. This work addresses a long-standing limitation in conventional cine MRI, which…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Zhengda Ma , Abhirup Banerjee

Myocardial perfusion imaging using SPECT is widely utilized to diagnose coronary artery diseases, but image quality can be negatively affected in low-dose and few-view acquisition settings. Although various deep learning methods have been…

Mesh reconstruction of the cardiac anatomy from medical images is useful for shape and motion measurements and biophysics simulations to facilitate the assessment of cardiac function and health. However, 3D medical images are often acquired…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Yihao Luo , Dario Sesia , Fanwen Wang , Yinzhe Wu , Wenhao Ding , Jiahao Huang , Fadong Shi , Anoop Shah , Amit Kaural , Jamil Mayet , Guang Yang , ChoonHwai Yap

Unsafe surgical care is a critical health concern, often linked to limitations in surgeon experience, skills, and situational awareness. Integrating patient-specific 3D models into the surgical field can enhance visualization, provide…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Alberto Neri , Veronica Penza , Nazim Haouchine , Leonardo S. Mattos

Image-based computer simulation of cardiac function can be used to probe the mechanisms of (patho)physiology, and guide diagnosis and personalized treatment of cardiac diseases. This paradigm requires constructing simulation-ready meshes of…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Fanwei Kong , Shawn C. Shadden

As diffusion tensor imaging (DTI) gains popularity in cardiac imaging due to its unique ability to non-invasively assess the cardiac microstructure, deep learning-based Artificial Intelligence is becoming a crucial tool in mitigating some…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 Michael Tanzer , Sea Hee Yook , Guang Yang , Daniel Rueckert , Sonia Nielles-Vallespin

Myocardial infarction causes myocardium thinning, fibrosis, and progressive heart failure. Engineered human myocardium (EHM) is tested clinically as a first-in-class product for sustainable remuscularization in patients with advanced heart…

Medical Physics · Physics 2025-08-28 Hossein Goodarzi Hosseinabadi

Owing to their intricate variable density architecture, and as a principal site of star formation, molecular clouds represent one of the most functionally significant, yet least understood features of our universe. To unravel the intrinsic…

Instrumentation and Methods for Astrophysics · Physics 2021-09-08 Nia Imara , John C. Forbes , James C. Weaver

The perfect alignment of 3D echocardiographic images captured from various angles has improved image quality and broadened the field of view. This study proposes an accelerated sequential Monte Carlo (SMC) algorithm for 3D-3D rigid…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Thanuja Uruththirakodeeswaran , Harald Becher , Michelle Noga , Lawrence H. Le , Pierre Boulanger , Jonathan Windram , Kumaradevan Punithakumar

Accurate 3D aortic construction is crucial for clinical diagnosis, preoperative planning, and computational fluid dynamics (CFD) simulations, as it enables the estimation of critical hemodynamic parameters such as blood flow velocity,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Delin An , Pan Du , Jian-Xun Wang , Chaoli Wang