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We introduce a new family of graphical models that consists of graphs with possibly directed, undirected and bidirected edges but without directed cycles. We show that these models are suitable for representing causal models with additive…

Machine Learning · Statistics 2017-05-30 Jose M. Peña , Marcus Bendtsen

This PhD thesis contains several contributions to the field of statistical causal modeling. Statistical causal models are statistical models embedded with causal assumptions that allow for the inference and reasoning about the behavior of…

Machine Learning · Statistics 2021-10-05 Martin Emil Jakobsen

Consider the problem of estimating the causal effect of some attribute of a text document; for example: what effect does writing a polite vs. rude email have on response time? To estimate a causal effect from observational data, we need to…

Machine Learning · Statistics 2023-02-09 Lin Gui , Victor Veitch

Identifying the effect of a treatment from observational data typically requires assuming a fully specified causal diagram. However, such diagrams are rarely known in practice, especially in complex or high-dimensional settings. To overcome…

Artificial Intelligence · Computer Science 2025-07-09 Clément Yvernes , Emilie Devijver , Marianne Clausel , Eric Gaussier

In classical causal inference, inferring cause-effect relations from data relies on the assumption that units are independent and identically distributed. This assumption is violated in settings where units are related through a network of…

Artificial Intelligence · Computer Science 2022-07-05 Razieh Nabi , Joel Pfeiffer , Murat Ali Bayir , Denis Charles , Emre Kıcıman

The fundamental challenge of drawing causal inference is that counterfactual outcomes are not fully observed for any unit. Furthermore, in observational studies, treatment assignment is likely to be confounded. Many statistical methods have…

Methodology · Statistics 2022-08-01 Harsh Parikh , Carlos Varjao , Louise Xu , Eric Tchetgen Tchetgen

Design-based causal inference, also known as randomization-based or finite-population causal inference, is one of the most widely used causal inference frameworks, largely due to the merit that its validity can be guaranteed by study design…

Methodology · Statistics 2025-05-27 Siyu Heng , Jiawei Zhang , Yang Feng

Many natural phenomena are intrinsically causal. The discovery of the cause-effect relationships implicit in these processes can help us to understand and describe them more effectively, which boils down to causal discovery about the data…

Quantitative Methods · Quantitative Biology 2024-01-09 Jean Pierre Gomez

Scientists often want to learn about cause and effect from hierarchical data, collected from subunits nested inside units. Consider students in schools, cells in patients, or cities in states. In such settings, unit-level variables (e.g.…

Methodology · Statistics 2024-06-27 Eli N. Weinstein , David M. Blei

Causal discovery is fundamental to scientific research, yet traditional statistical algorithms face significant challenges, including expensive data collection, redundant computation for known relations, and unrealistic assumptions. While…

Computation and Language · Computer Science 2025-10-13 Tao Feng , Lizhen Qu , Niket Tandon , Gholamreza Haffari

Knowing the effect of an intervention is critical for human decision-making, but current approaches for causal effect estimation rely on manual data collection and structuring, regardless of the causal assumptions. This increases both the…

Machine Learning · Computer Science 2024-10-29 Nikita Dhawan , Leonardo Cotta , Karen Ullrich , Rahul G. Krishnan , Chris J. Maddison

Uncovering causal relationships in data is a major objective of data analytics. Causal relationships are normally discovered with designed experiments, e.g. randomised controlled trials, which, however are expensive or infeasible to be…

Artificial Intelligence · Computer Science 2016-11-01 Jiuyong Li , Saisai Ma , Thuc Duy Le , Lin Liu , Jixue Liu

Causal inference methods based on electronic health record (EHR) databases must simultaneously handle confounding and missing data. Vast scholarship exists aimed at addressing these two issues separately, but surprisingly few papers attempt…

Methodology · Statistics 2025-07-28 Luke Benz , Alexander Levis , Sebastien Haneuse

Causal inference for testing clinical hypotheses from observational data presents many difficulties because the underlying data-generating model and the associated causal graph are not usually available. Furthermore, observational data may…

Causal diagrams based on do intervention are useful tools to formalize, process and understand causal relationship among variables. However, the do intervention has controversial interpretation of causal questions for non-manipulable…

Artificial Intelligence · Computer Science 2020-06-03 Gong Heyang , Zhu Ke

Identifying the effects of causes and causes of effects is vital in virtually every scientific field. Often, however, the needed probabilities may not be fully identifiable from the data sources available. This paper shows how partial…

Artificial Intelligence · Computer Science 2023-01-31 Ang Li , Scott Mueller , Judea Pearl

The cause-to-effect analysis can help us decompose all the likely causes of a problem, such as an undesirable business situation or unintended harm to the individual(s). This implies that we can identify how the problems are inherited, rank…

Machine Learning · Computer Science 2023-10-20 Moses Openja , Gabriel Laberge , Foutse Khomh

Most traditional models of uncertainty have focused on the associational relationship among variables as captured by conditional dependence. In order to successfully manage intelligent systems for decision making, however, we must be able…

Artificial Intelligence · Computer Science 2015-05-19 David Heckerman , Ross D. Shachter

Causal inference is to estimate the causal effect in a causal relationship when intervention is applied. Precisely, in a causal model with binary interventions, i.e., control and treatment, the causal effect is simply the difference between…

Machine Learning · Computer Science 2022-07-19 Zhenyu Lu , Yurong Cheng , Mingjun Zhong , George Stoian , Ye Yuan , Guoren Wang

In the context of having an instrumental variable, the standard practice in causal inference begins by targeting an effect of interest and proceeds by formulating assumptions enabling its identification. We turn this around by adhering to…

Statistics Theory · Mathematics 2026-05-25 Carlos García Meixide , Mark J. van der Laan