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Despite the wide existence of vesicles in living cells as well as their important applications like drug-delivery, the underlying mechanism of vesicle fusion/fission remains under debate. Here, we develop a constrained self-consistent field…

Soft Condensed Matter · Physics 2023-05-22 Luofu Liu , Chao Duan , Rui Wang

Atomically thin 2-dimensional heterostructures are a promising, novel class of materials with groundbreaking properties. The possiblity of choosing the many constituent components and their proportions allows optimizing these materials to…

Mesoscale and Nanoscale Physics · Physics 2019-10-23 Petri Hirvonen , Vili Heinonen , Haikuan Dong , Zheyong Fan , Ken R. Elder , Tapio Ala-Nissila

We propose a numerical method for fluid deformable surfaces governed by surface Stokes flow and Helfrich bending energy under active growth, aiming to model shape evolution of the epithelium in developmental processes. To prevent…

Fluid Dynamics · Physics 2026-02-17 Maik Porrmann , Sören Bartels , Axel Voigt

In simulations of crystals, unlike liquids or gases, it may happen that the properties of the studied system depend not only on the volume of the simulation cell but also on its shape. For such cases it is desirable to change the shape of…

Computational Physics · Physics 2022-10-04 A. Baumketner

The wrapping of particles and vesicles by lipid bilayer membranes is a fundamental process in cellular transport and targeted drug delivery. Here, we investigate the wrapping behavior of nonspherical vesicles, such as ellipsoidal, prolate,…

Soft Condensed Matter · Physics 2025-02-18 Ajit Kumar Sahu , Rajkumar Malik , Jiarul Midya

Most approaches in Lagrangian fluid dynamics simulations proceed from the definition of particle volumes, from which discrete versions of the spatial differential operators are derived. Recently, Gallou\"et and M\'erigot [1] simultaneously…

Fluid Dynamics · Physics 2023-01-25 Daniel Duque

Validation of deformable image registration techniques is extremely important, but hard, especially when complex deformations or content mismatch are involved. These complex deformations and content mismatch, for example, occur after the…

Morphologies of a vesicle confined in a spherical vesicle were explored experimentally by fast confocal laser microscopy and numerically by a dynamically-triangulated membrane model with area-difference elasticity. The confinement was found…

Soft Condensed Matter · Physics 2014-04-08 Ai Sakashita , Masayuki Imai , Hiroshi Noguchi

Gel-elastomer composites, comprising an active swellable hydrogel and a passive elastomer, are a compelling class of programmable material systems (PMS) capable of shape morphing under multiphysics actuation. The precise design of the…

Computational Engineering, Finance, and Science · Computer Science 2026-05-20 Aaditya Chandrasekhar , Dex Doksoo Lee , Hyunwoo Kwon , Wei Chen

Recent advancements in finite element methods allows for the implementation of mesh cells with curved edges. In the present work, we develop the tools necessary to employ multiply connected mesh cells, i.e. cells with holes, in planar…

Numerical Analysis · Mathematics 2023-03-15 Jeffrey S. Ovall , Samuel E. Reynolds

We introduce and analyze a lower envelope method (LEM) for the tracking of interfaces motion in multiphase problems. The main idea of the method is to define the phases as the regions where the lower envelope of a set of functions coincides…

Numerical Analysis · Mathematics 2021-12-07 Antoine Laurain

Complex colloidal fluids, such as emulsions stabilized by complex shaped particles, play an important role in many industrial applications. However, understanding their physics requires a study at sufficiently large length scales while…

Soft Condensed Matter · Physics 2012-04-27 Florian Günther , Florian Janoschek , Stefan Frijters , Jens Harting

In active matter systems, deformable boundaries provide a mechanism to organize internal active stresses and perform work on the external environment. To study a minimal model of such a system, we perform particle-based simulations of an…

Soft Condensed Matter · Physics 2022-01-05 Matthew S. E. Peterson , Aparna Baskaran , Michael F. Hagan

This article presents new hexagonal and pentagonal PEM fuel cell models. The models have been optimized after achieving improved cell performance. The input parameters of the multi-objective optimization algorithm were pressure and…

Neural and Evolutionary Computing · Computer Science 2023-10-18 Ali Jabbary , Nader Pourmahmoud , Mir Ali Asghar Abdollahi , Marc A. Rosen

Glassy dynamics in a confluent monolayer is indispensable in morphogenesis, wound healing, bronchial asthma, and many others; a detailed theoretical framework for such a system is, therefore, important. Vertex model (VM) simulations have…

Soft Condensed Matter · Physics 2021-06-16 Souvik Sadhukhan , Saroj Kumar Nandi

The Boltzmann equation, as a model equation in statistical mechanics, is used to describe the statistical behavior of a large number of particles driven by the same physics laws. Depending on the media and the particles to be modeled, the…

Numerical Analysis · Mathematics 2019-04-16 Eric Chung , Yalchin Efendiev , Yanbo Li , Qin Li

We propose a computational framework for vascular fluid-structure interaction (FSI), focusing on biomechanical modeling, geometric modeling, and solver technology. The biomechanical model is constructed based on the unified continuum…

Fluid Dynamics · Physics 2022-06-27 Ju Liu , Jiayi Huang , Qingshuang Lu , Yujie Sun

Over the past few decades, in silico modeling of organ systems has significantly furthered our understanding of their physiology and biomechanical function. In this work, we present a detailed numerical model of the upper gastrointestinal…

Spaces where each element describes a shape, so-called shape spaces, are of particular interest in shape optimization and its applications. Theory and algorithms in shape optimization are often based on techniques from differential…

Optimization and Control · Mathematics 2025-04-01 Lidiya Pryymak , Tim Suchan , Kathrin Welker

An important task at the onset of a laparoscopic cholecystectomy (LC) operation is the inspection of gallbladder (GB) to evaluate the thickness of its wall, presence of inflammation and extent of fat. Difficulty in visualization of the GB…

Computer Vision and Pattern Recognition · Computer Science 2021-07-29 C. Loukas , A. Gazis , D. Schizas