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A multiphysics phase field model is used for the computational study of memristive thin film morphology and current-voltage hysteresis. In contrast to previous computational methods, no requirements are made on conducting filament geometry.…

Materials Science · Physics 2025-06-24 John F. Sevic , Ambroise Juston , Nobuhiko P. Kobayashi

The morphologies of genus-2 to -8 fluid vesicles are studied by using dynamically triangulated membrane simulations with area-difference elasticity. It is revealed that the alignments of the membrane pores alter the vesicle shapes and the…

Soft Condensed Matter · Physics 2015-12-22 Hiroshi Noguchi

Fluid-Structure Interaction (FSI) can be investigated by means of non-linear Finite Element Models (FEM), suitable to capture large deflections of structural parts interacting with fluids, and Computational Fluid Dynamics (CFD). High…

Since its discovery, the deep-sea glass sponge Euplectella aspergillum has attracted interest in its mechanical properties and beauty. Its skeletal system is composed of amorphous hydrated silica and is arranged in a highly regular and…

In the field of parametric partial differential equations, shape optimization represents a challenging problem due to the required computational resources. In this contribution, a data-driven framework involving multiple reduction…

Numerical Analysis · Mathematics 2021-02-23 Nicola Demo , Marco Tezzele , Andrea Mola , Gianluigi Rozza

An important step in shape optimization with partial differential equation constraints is to adapt the geometry during each optimization iteration. Common strategies are to employ mesh-deformation or re-meshing, where one or the other…

Numerical Analysis · Mathematics 2018-06-27 Jorgen S. Dokken , Simon W. Funke , August Johansson , Stephan Schmidt

The mechanisms controlling the transport of proteins across the Golgi stack of mammalian and plant cells is the subject of intense debate, with two models, cisternal progression and inter-cisternal exchange, emerging as major contenders. A…

Subcellular Processes · Quantitative Biology 2014-03-05 Serge Dmitrieff , Madan Rao , Pierre Sens

The inner membrane of mitochondria presents folds, the cristae, which are the production place of ATP. This synthesis is driven by a flow of protons confined to the surface of the membrane, which also shapes the crista to ensure a high…

Biological Physics · Physics 2025-02-11 Yorgos Chatziantoniou , Hélène Berthoumieux

It is well known that the solution of topology optimization problems may be affected both by the geometric properties of the computational mesh, which can steer the minimization process towards local (and non-physical) minima, and by the…

Numerical Analysis · Mathematics 2016-12-28 Paola F. Antonietti , Matteo Bruggi , Simone Scacchi , Marco Verani

In order to describe two-dimensionally packed cells in epithelial tissues both mathematically and physically, there have been developed several sorts of geometrical models, such as the vertex model, the finite element model, the…

Biological Physics · Physics 2014-11-19 Yukitaka Ishimoto , Yoshihiro Morishita

Topology optimization is concerned with the identification of optimal shapes of deformable bodies with respect to given target functionals. The focus of this paper is on a topology optimization problem for a time-evolving elastoplastic…

Analysis of PDEs · Mathematics 2021-06-21 Stefano Almi , Ulisse Stefanelli

Thermally aware design of 2.5D and 3D advanced packaging systems will require fast, accurate, and powerful thermal analysis of chiplets, stacks, and packages. These systems contain multiple materials with non-linear heat transfer properties…

Topology optimization of microstructures plays a critical role in optimizing functional performance across diverse engineering applications. While metamaterials with enhanced mechanical properties -- such as hyperelasticity, energy…

Soft Condensed Matter · Physics 2025-01-27 Weiming Wang , Yanhao Hou , Renbo Su , Weiguang Wang , Charlie C. L. Wang

Meshing complex engineering domains is a challenging task. Arbitrary polyhedral meshes can provide the much needed flexibility in automated discretization of such domains. The geometric property of the polyhedral meshes such as the…

Optimization and Control · Mathematics 2015-07-22 Arun L. Gain , Glaucio H. Paulino , Leonardo Duarte , Ivan F. M. Menezes

This paper proposes a level set-based method for optimizing shell structures with large design changes in shape and topology. Conventional shell optimization methods, whether parametric or nonparametric, often only allow limited design…

Computational Engineering, Finance, and Science · Computer Science 2024-08-29 Hiroki Kobayashi , Katsuya Nomura , Yuqing Zhou , Masato Tanaka , Atsushi Kawamoto , Tsuyoshi Nomura

We present a computational framework for modeling large-scale particle-laden flows in complex domains with the goal of enabling simulations in medical-image derived patient specific geometries. The framework is based on a volume-filtered…

Fluid Dynamics · Physics 2023-11-28 Abhilash Reddy Malipeddi , C. Alberto Figueroa , Jesse Capecelatro

A new field of numerical astrophysics is introduced which addresses the solution of large, multidimensional structural or slowly-evolving problems (rotating stars, interacting binaries, thick advective accretion disks, four dimensional…

Astrophysics · Physics 2009-10-30 David L. Meier

In this paper we are interested in optimizing the shape of multi-flagellated helical microswimmers. Mimicking the propagation of helical waves along the flagella, they self-propel by rotating their tails. The swimmer's dynamics is computed…

Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…

Soft Condensed Matter · Physics 2025-09-15 Didarul Ahasan Redwan , Justin Reicher , Xin Yong

Engineering alloys generally exhibit multi-phase microstructures. For simulating their microstructure evolution during solid-state phase transformation, CALPHAD-guided multi-phase-field models coupled with micro-mechanics have proven to be…

Materials Science · Physics 2023-01-05 Sourav Chatterjee , Daniel Schwen , Nele Moelans