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Deep generative models (DGMs) have the potential to revolutionize diagnostic imaging. Generative adversarial networks (GANs) are one kind of DGM which are widely employed. The overarching problem with deploying GANs, and other DGMs, in any…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Rucha Deshpande , Mark A. Anastasio , Frank J. Brooks

The overexpression of the human epidermal growth factor receptor 2 (HER2) in breast cells is a key driver of HER2-positive breast cancer, a highly aggressive subtype requiring precise diagnosis and targeted therapy. Immunohistochemistry…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Sara Rehmat , Hafeez Ur Rehman , Byeong-Gwon Kang , Sarra Ayouni , Yunyoung Nam

We present a novel conditional Generative Adversarial Network (cGAN) architecture that is capable of generating 3D Computed Tomography scans in voxels from noisy and/or pixelated approximations and with the potential to generate full…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Jayalakshmi Mangalagiri , David Chapman , Aryya Gangopadhyay , Yaacov Yesha , Joshua Galita , Sumeet Menon , Yelena Yesha , Babak Saboury , Michael Morris , Phuong Nguyen

Synthetic CT image generation from MRI scan is necessary to create radiotherapy plans without the need of co-registered MRI and CT scans. The chosen baseline adversarial model with cycle consistency permits unpaired image-to-image…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Denis Prokopenko , Joël Valentin Stadelmann , Heinrich Schulz , Steffen Renisch , Dmitry V. Dylov

Purpose A Magnetic Resonance Imaging (MRI) exam typically consists of several sequences that yield different image contrasts. Each sequence is parameterized through multiple acquisition parameters that influence image contrast,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Jonas Denck , Jens Guehring , Andreas Maier , Eva Rothgang

High-resolution magnetic resonance images can provide fine-grained anatomical information, but acquiring such data requires a long scanning time. In this paper, a framework called the Fused Attentive Generative Adversarial Networks(FA-GAN)…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Mingfeng Jiang , Minghao Zhi , Liying Wei , Xiaocheng Yang , Jucheng Zhang , Yongming Li , Pin Wang , Jiahao Huang , Guang Yang

Recently deep learning methods, in particular, convolutional neural networks (CNNs), have led to a massive breakthrough in the range of computer vision. Also, the large-scale annotated dataset is the essential key to a successful training…

Image and Video Processing · Electrical Eng. & Systems 2020-11-17 Chang Qi , Junyang Chen , Guizhi Xu , Zhenghua Xu , Thomas Lukasiewicz , Yang Liu

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…

During their formative years, radiology trainees are required to interpret hundreds of mammograms per month, with the objective of becoming apt at discerning the subtle patterns differentiating benign from malignant lesions. Unfortunately,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-26 Cyril Zakka , Ghida Saheb , Elie Najem , Ghina Berjawi

Automated lesion segmentation from computed tomography (CT) is an important and challenging task in medical image analysis. While many advancements have been made, there is room for continued improvements. One hurdle is that CT images can…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Youbao Tang , Jinzheng Cai , Le Lu , Adam P. Harrison , Ke Yan , Jing Xiao , Lin Yang , Ronald M. Summers

Objective: To assess the performance of a probabilistic deep learning based algorithm for predicting inter-fraction anatomical changes in head and neck patients. Approach: A probabilistic daily anatomy model for head and neck patients…

Medical Physics · Physics 2024-11-12 Tiberiu Burlacu , Mischa Hoogeman , Danny Lathouwers , Zoltán Perkó

Despite the recent success in applying supervised deep learning to medical imaging tasks, the problem of obtaining large and diverse expert-annotated datasets required for the development of high performant models remains particularly…

Computer Vision and Pattern Recognition · Computer Science 2019-11-21 Amirata Ghorbani , Vivek Natarajan , David Coz , Yuan Liu

Purpose: To evaluate deep learning (DL) models for enhancing vitreous optical coherence tomography (OCT) image quality and reducing acquisition time. Methods: Conditional Denoising Diffusion Probabilistic Models (cDDPMs), Brownian Bridge…

Image and Video Processing · Electrical Eng. & Systems 2025-11-05 Simone Sarrocco , Philippe C. Cattin , Peter M. Maloca , Paul Friedrich , Philippe Valmaggia

In medical imaging, image synthesis is the estimation process of one image (sequence, modality) from another image (sequence, modality). Since images with different modalities provide diverse biomarkers and capture various features,…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Firoozeh Shomal Zadeh , Sevda Molani , Maysam Orouskhani , Marziyeh Rezaei , Mehrzad Shafiei , Hossein Abbasi

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr

Generative Adversarial Networks (GANs) have been at the forefront of image synthesis, especially in medical fields like histopathology, where they help address challenges such as data scarcity, patient privacy, and class imbalance. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Osama Mustafa

With the increasing popularity of PET-MR scanners in clinical applications, synthesis of CT images from MR has been an important research topic. Accurate PET image reconstruction requires attenuation correction, which is based on the…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Snehashis Roy , John A. Butman , Dzung L. Pham

In medical imaging, access to data is commonly limited due to patient privacy restrictions and the issue that it can be difficult to acquire enough data in the case of rare diseases.[1] The purpose of this investigation was to develop a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 John R. McNulty , Lee Kho , Alexandria L. Case , Charlie Fornaca , Drew Johnston , David Slater , Joshua M. Abzug , Sybil A. Russell

Magnetic Resonance Imaging (MRI) of the brain has been used to investigate a wide range of neurological disorders, but data acquisition can be expensive, time-consuming, and inconvenient. Multi-site studies present a valuable opportunity to…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Harrison Nguyen , Richard W. Morris , Anthony W. Harris , Mayuresh S. Korgoankar , Fabio Ramos

Medical datasets are often highly imbalanced with over-representation of common medical problems and a paucity of data from rare conditions. We propose simulation of pathology in images to overcome the above limitations. Using chest X-rays…

Computer Vision and Pattern Recognition · Computer Science 2018-02-13 Hojjat Salehinejad , Shahrokh Valaee , Tim Dowdell , Errol Colak , Joseph Barfett