Related papers: Modeling the Mitral Valve
A central problem in biomechanical studies of personalised human left ventricular (LV) modelling is estimating the material properties and biophysical parameters from in-vivo clinical measurements in a time frame suitable for use within a…
Many approaches have been used to model chordae tendineae geometries in finite element simulations of atrioventricular heart valves. Unfortunately, current "functional" chordae tendineae geometries lack fidelity that would be helpful when…
The shell map is a very simple representation of the structure of foams, combining the geometrical (random tiling) and dynamical (loss of information from an arbitrary cell out) aspects of disorder. The structure is built from the central…
The red blood cell (RBC) membrane is composed of a lipid bilayer and a cytoskeleton interconnected by protein junction complexes, allowing for potential sliding between the lipid bilayer and the cytoskeleton. Despite this biological…
The assembly of banana-shaped rodlike proteins on membranes, and the associated membrane shape transformations, are investigated by analytical theory and coarse-grained simulations. The membrane-mediated interactions between two…
The efficient construction of anatomical models is one of the major challenges of patient-specific in-silico models of the human heart. Current methods frequently rely on linear statistical models, allowing no advanced topological changes,…
Molecular clouds are supported by thermal pressure, magnetic pressure, and turbulent pressure. Each of these can be modeled with a polytropic equation of state, so that overall the total pressure is the sum of the individual components. We…
Pressure-relief valves, often the critical last line of defence in process engineering, are known to be susceptible to valve chatter. Such behaviour has been shown to arise from a flutter instability, or Hopf bifurcation, associated with…
We present a continuum level analytical model of a droplet of active contractile fluid consisting of filaments and motors. We calculate the steady state flows that result from a splayed polarisation of the filaments. We account for the…
Cell extrusion is an essential mechanism for controlling cell density in epithelial tissues. Another essential element of epithelia is curvature, which is required to achieve complex shapes, like in the lung or intestine. Here we introduce…
One-dimensional blood flow model accuracy has been verified in many studies. This work is about introducing gravity into a one-dimensional model. For this purpose, gravitational force was introduced into the existing model. The boundary…
To move away from open-heart surgery towards safer transcatheter procedures, there is a growing need for improved imaging techniques and robotic solutions to enable simple, accurate tool navigation. Common imaging modalities, such as…
Although research studies in pneumatic soft robots develop rapidly, most pneumatic actuators are still controlled by rigid valves and conventional electronics. The existence of these rigid, electronic components sacrifices the compliance…
Deformation modeling of cardiac muscle is an important issue in the field of cardiac analysis. Many approaches have been developed to better estimate the cardiac muscle deformation, and to obtain a practical model to be used in diagnostic…
This paper presents a recurrent neural network approach to simulating mechanical ventilator pressure. The traditional mechanical ventilator has a control pressure that is monitored by a medical practitioner and can behave incorrectly if the…
Computer simulation of "virtual interventions" may inform optimal valve repair for a given patient prior to intervention. However, the paucity of noninvasive methods to determine in vivo mechanical parameters of valves limits the accuracy…
In this article, we review the mathematical modeling for the vascular system.
The vertex model is a popular framework for modelling tightly packed biological cells, such as confluent epithelia. Cells are described by convex polygons tiling the plane and their equilibrium is found by minimizing a global mechanical…
Valveless pumping assists in fluid transport in various organisms and engineering systems. In a previous work, to study the actuator impact effects on valveless pumping, we constructed a piecewise-linear lumped-parameter model for a…
When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering…