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Deep learning has revolutionized medical and biological imaging, particularly in segmentation tasks. However, segmenting biological cells remains challenging due to the high variability and complexity of cell shapes. Addressing this…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Tianhao Zhang , Heather J. McCourty , Berardo M. Sanchez-Tafolla , Anton Nikolaev , Lyudmila S. Mihaylova

Non-rigid inter-modality registration can facilitate accurate information fusion from different modalities, but it is challenging due to the very different image appearances across modalities. In this paper, we propose to train a non-rigid…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Xiaohuan Cao , Jianhua Yang , Li Wang , Zhong Xue , Qian Wang , Dinggang Shen

Multi-modal magnetic resonance (MR) imaging provides great potential for diagnosing and analyzing brain gliomas. In clinical scenarios, common MR sequences such as T1, T2 and FLAIR can be obtained simultaneously in a single scanning…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ziqi Huang , Li Lin , Pujin Cheng , Linkai Peng , Xiaoying Tang

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

When oncologists estimate cancer patient survival, they rely on multimodal data. Even though some multimodal deep learning methods have been proposed in the literature, the majority rely on having two or more independent networks that share…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Numan Saeed , Ikboljon Sobirov , Roba Al Majzoub , Mohammad Yaqub

Accurate segmentation of brain tumors from multi-modal Magnetic Resonance (MR) images is essential in brain tumor diagnosis and treatment. However, due to the existence of domain shifts among different modalities, the performance of…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Kelei He , Wen Ji , Tao Zhou , Zhuoyuan Li , Jing Huo , Xin Zhang , Yang Gao , Dinggang Shen , Bing Zhang , Junfeng Zhang

Despite the remarkable performance of supervised medical image segmentation models, relying on a large amount of labeled data is impractical in real-world situations. Semi-supervised learning approaches aim to alleviate this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yunyao Lu , Yihang Wu , Ahmad Chaddad , Tareef Daqqaq , Reem Kateb

Domain shift has been a long-standing issue for medical image segmentation. Recently, unsupervised domain adaptation (UDA) methods have achieved promising cross-modality segmentation performance by distilling knowledge from a label-rich…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Ziyuan Zhao , Kaixin Xu , Huai Zhe Yeo , Xulei Yang , Cuntai Guan

This paper proposes a 3D attention-based U-Net architecture for multi-region segmentation of brain tumors using a single stacked multi-modal volume created by combining three non-native MRI volumes. The attention mechanism added to the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maryann M. Gitonga

Medical image segmentation has significantly benefitted thanks to deep learning architectures. Furthermore, semi-supervised learning (SSL) has recently been a growing trend for improving a model's overall performance by leveraging abundant…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 S. M. Kamrul Hasan , Cristian A. Linte

Accurate segmentation of laryngo-pharyngeal tumors is crucial for precise diagnosis and effective treatment planning. However, traditional single-modality imaging methods often fall short of capturing the complex anatomical and pathological…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Junhao Wu , Yun Li , Junhao Li , Jingliang Bian , Xiaomao Fan , Wenbin Lei , Ruxin Wang

Recent advances in deep learning-based medical image segmentation studies achieve nearly human-level performance when in fully supervised condition. However, acquiring pixel-level expert annotations is extremely expensive and laborious in…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Hyungseob Shin , Hyeongyu Kim , Sewon Kim , Yohan Jun , Taejoon Eo , Dosik Hwang

Deep learning techniques, particularly convolutional neural networks, have shown great potential in computer vision and medical imaging applications. However, deep learning models are computationally demanding as they require enormous…

Signal Processing · Electrical Eng. & Systems 2022-06-07 Owais Ali , Hazrat Ali , Syed Ayaz Ali Shah , Aamir Shahzad

Brain tumor imaging has been part of the clinical routine for many years to perform non-invasive detection and grading of tumors. Tumor segmentation is a crucial step for managing primary brain tumors because it allows a volumetric analysis…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Masoomeh Rahimpour , Ahmed Radwan , Henri Vandermeulen , Stefan Sunaert , Karolien Goffin , Michel Koole

Brain metastasis segmentation poses a significant challenge in medical imaging due to the complex presentation and variability in size and location of metastases. In this study, we first investigate the impact of different imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Yousef Sadegheih , Dorit Merhof

Image segmentation is a fundamental problem in medical image analysis. In recent years, deep neural networks achieve impressive performances on many medical image segmentation tasks by supervised learning on large manually annotated data.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-26 Ling Zhang , Vissagan Gopalakrishnan , Le Lu , Ronald M. Summers , Joel Moss , Jianhua Yao

Prostate cancer is the second leading cause of cancer death among men in the United States. The diagnosis of prostate MRI often relies on the accurate prostate zonal segmentation. However, state-of-the-art automatic segmentation methods…

Image and Video Processing · Electrical Eng. & Systems 2022-06-20 Alex Ling Yu Hung , Haoxin Zheng , Qi Miao , Steven S. Raman , Demetri Terzopoulos , Kyunghyun Sung

This paper proposes a novel framework for lung segmentation in chest X-rays. It consists of two key contributions, a criss-cross attention based segmentation network and radiorealistic chest X-ray image synthesis (i.e. a synthesized…

Computer Vision and Pattern Recognition · Computer Science 2019-04-22 Youbao Tang , Yuxing Tang , Jing Xiao , Ronald M. Summers

Automated detection and segmentation of pulmonary nodules on lung computed tomography (CT) scans can facilitate early lung cancer diagnosis. Existing supervised approaches for automated nodule segmentation on CT scans require voxel-based…

Computer Vision and Pattern Recognition · Computer Science 2018-02-26 Xinyang Feng , Jie Yang , Andrew F. Laine , Elsa D. Angelini

The accurate segmentation of lesions in whole-body PET/CT imaging is es-sential for tumor characterization, treatment planning, and response assess-ment, yet current manual workflows are labor-intensive and prone to inter-observer…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Moona Mazher , Steven A Niederer , Abdul Qayyum