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Diagnosis and treatment management for head and neck squamous cell carcinoma (HNSCC) is guided by routine diagnostic head and neck computed tomography (CT) scans to identify tumor and lymph node features. Extracapsular extension (ECE) is a…
Segmentation and classification of cell nuclei in histopathology images using deep neural networks (DNNs) can save pathologists' time for diagnosing various diseases, including cancers, by automating cell counting and morphometric…
Autoencoders have been extensively used in the development of recent anomaly detection techniques. The premise of their application is based on the notion that after training the autoencoder on normal training data, anomalous inputs will…
High-resolution mapping of cells and tissue structures provides a foundation for developing interpretable machine-learning models for computational pathology. Deep learning algorithms can provide accurate mappings given large numbers of…
A web-based tool called ADFilter was developed to process collision events using autoencoders based on a deep unsupervised neural network. The autoencoders are trained on a small fraction of either collision data or Standard Model Monte…
Unsupervised learning-based anomaly detection in latent space has gained importance since discriminating anomalies from normal data becomes difficult in high-dimensional space. Both density estimation and distance-based methods to detect…
Lung cancer is responsible for 21% of cancer deaths in the UK and five-year survival rates are heavily influenced by the stage the cancer was identified at. Recent studies have demonstrated the capability of AI methods for accurate and…
Reconstruction-based approaches to anomaly detection tend to fall short when applied to complex datasets with target classes that possess high inter-class variance. Similar to the idea of self-taught learning used in transfer learning, many…
Can a single label-free image reveal whether cancer cells were exposed to chemotherapy? We present an innovative methodology on the label-free and high-resolution imaging properties of phase holotomographic microscopy coupled with neural…
In deep learning for drug discovery, chemical data are often represented as simplified molecular-input line-entry system (SMILES) sequences which allow for straightforward implementation of natural language processing methodologies, one…
We present an autoencoder that leverages learned representations to better measure similarities in data space. By combining a variational autoencoder with a generative adversarial network we can use learned feature representations in the…
This work proposes an autoencoder neural network as a non-linear generalization of projection-based methods for solving Partial Differential Equations (PDEs). The proposed deep learning architecture presented is capable of generating the…
This study explores the application of supervised and unsupervised autoencoders (AEs) to automate nuclei classification in clear cell renal cell carcinoma (ccRCC) images, a diagnostic task traditionally reliant on subjective visual grading…
In the current technological era, the medical profession has emerged as one of the researchers' favorite subject areas, and cancer is one of them. Because there is now no effective treatment for this illness, it is a matter of concern. Only…
Autoencoders are unsupervised deep learning models used for learning representations. In literature, autoencoders have shown to perform well on a variety of tasks spread across multiple domains, thereby establishing widespread…
Leukemia is one of the most common and death-threatening types of cancer that threaten human life. Medical data from some of the patient's critical parameters contain valuable information hidden among these data. On this subject, deep…
Cancer survival prediction is important for developing personalized treatments and inducing disease-causing mechanisms. Multi-omics data integration is attracting widespread interest in cancer research for providing information for…
There has been a lot of recent interest in designing neural network models to estimate a distribution from a set of examples. We introduce a simple modification for autoencoder neural networks that yields powerful generative models. Our…
Deep learning classifiers for characterization of whole slide tissue morphology require large volumes of annotated data to learn variations across different tissue and cancer types. As is well known, manual generation of digital pathology…
Several machine learning techniques for accurate detection of skin cancer from medical images have been reported. Many of these techniques are based on pre-trained convolutional neural networks (CNNs), which enable training the models based…