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The human brain is a complex network of interconnected brain regions organized into functional modules with distinct roles in cognition and behavior. An important question concerns the persistence and stability of these modules over the…

Neurons and Cognition · Quantitative Biology 2015-10-28 Richard F. Betzel , Bratislav Mišić , Ye He , Jeffrey Rumschlag , Xi-Nian Zuo , Olaf Sporns

Evidence suggests that brain network dynamics is a key determinant of brain function and dysfunction. Here we propose a new framework to assess the dynamics of brain networks based on recurrence analysis. Our framework uses recurrence plots…

Neurons and Cognition · Quantitative Biology 2020-09-17 Marinho A. Lopes , Jiaxiang Zhang , Dominik Krzemiński , Khalid Hamandi , Qi Chen , Lorenzo Livi , Naoki Masuda

Typical brain networks consist of many peripheral regions and a few highly central ones, i.e. hubs, playing key functional roles in cerebral inter-regional interactions. Studies have shown that networks, obtained from the analysis of…

Neurons and Cognition · Quantitative Biology 2016-07-19 Manlio De Domenico , Shuntaro Sasai , Alex Arenas

At rest, human brain functional networks display striking modular architecture in which coherent clusters of brain regions are activated. The modular account of brain function is pervasive, reliable, and reproducible. Yet, a complementary…

The brain continually reorganizes its functional network to adapt to post-stroke functional impairments. Previous studies using static modularity analysis have presented global-level behavior patterns of this network reorganization.…

Computation · Statistics 2024-03-25 Kaichao Wu , Beth Jelfs , Katrina Neville , Wenzhen He , Qiang Fang

Cognitive fatigue, which transitions from focused attention to inexact responses, can cause catastrophic failures in high-stakes environments, yet current black-box assessment techniques ignore the brain's non-Markovian and time-varying…

Human-Computer Interaction · Computer Science 2026-05-05 Zeinabsadat Saghi , Daria Riabukhina , Olubukola Akinbami , Paul Bogdan , Souti Chattopadhyay

Functional magnetic resonance imaging (fMRI) is a neuroimaging technique that records neural activations in the brain by capturing the blood oxygen level in different regions based on the task performed by a subject. Given fMRI data, the…

Computer Vision and Pattern Recognition · Computer Science 2021-09-21 Ashish Jaiswal , Ashwin Ramesh Babu , Mohammad Zaki Zadeh , Fillia Makedon , Glenn Wylie

In systems and network neuroscience, many common practices in brain connectomic analysis are often not properly scrutinized. One such practice is mapping a predetermined set of sub-circuits, like functional networks (FNs), onto subjects'…

Today, the human brain can be studied as a whole. Electroencephalography, magnetoencephalography, or functional magnetic resonance imaging techniques provide functional connectivity patterns between different brain areas, and during…

Data Analysis, Statistics and Probability · Physics 2011-01-21 Mario Chavez , Miguel Valencia , Vito Latora , Jacques Martinerie

This paper presents preliminary results in the definition of a comprehensive benchmark framework designed to systematically evaluate spatial reasoning capabilities in neural networks, with a particular focus on morphological properties such…

Machine Learning · Computer Science 2025-08-19 Manuela Imbriani , Gina Belmonte , Mieke Massink , Alessandro Tofani , Vincenzo Ciancia

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

Disordered Systems and Neural Networks · Physics 2021-02-11 Ali Safari , Paolo Moretti , Ibai Diez , Jesus M. Cortes , Miguel Ángel Muñoz

The network architecture of the human brain has become a feature of increasing interest to the neuroscientific community, largely because of its potential to illuminate human cognition, its variation over development and aging, and its…

Neurons and Cognition · Quantitative Biology 2016-11-07 Richard F. Betzel , Danielle S. Bassett

Open problems abound in the theory of complex networks, which has found successful application to diverse fields of science. With the aim of further advancing the understanding of the brain's functional connectivity, we propose to evaluate…

Neurons and Cognition · Quantitative Biology 2019-02-20 A. Viol , Fernanda Palhano-Fontes , Heloisa Onias , Draulio B. de Araujo , Philipp Hövel , G. M. Viswanathan

Humans excel at adapting perceptions and actions to diverse environments, enabling efficient interaction with the external world. This adaptive capability relies on the biological nervous system (BNS), which activates different brain…

Machine Learning · Computer Science 2024-11-12 Jingyao Wang , Huijie Guo , Wenwen Qiang , Jiangmeng Li , Changwen Zheng , Hui Xiong , Gang Hua

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

Methodology · Statistics 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

The human brain receives complex inputs when performing cognitive tasks, which range from external inputs via the senses to internal inputs from other brain regions. However, the explicit inputs to the brain during a cognitive task remain…

Neurons and Cognition · Quantitative Biology 2024-04-26 Zhichao Liang , Yinuo Zhang , Jushen Wu , Quanying Liu

The foundation of cognitive flexibility and higher-order intelligence lies in the functional structure and activity of brain networks, which can be dynamically configured by both external environments and internal states. However, decoding…

Neurons and Cognition · Quantitative Biology 2026-04-28 Binghao Yang , Guangzong Chen

Effective analysis in neuroscience benefits significantly from robust conceptual frameworks. Traditional metrics of interbrain synchrony in social neuroscience typically depend on fixed, correlation-based approaches, restricting their…

Neurons and Cognition · Quantitative Biology 2025-12-01 Nicolás Hinrichs , Noah Guzmán , Melanie Weber

We propose a complexity measure which addresses the functional flexibility of networks. It is conjectured that the functional flexibility is reflected in the topological diversity of the assigned graphs, resulting from a resolution of their…

Condensed Matter · Physics 2009-11-10 Hildegard Meyer-Ortmanns