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Many animals in their natural habitat exhibit collective motion and form complex patterns to tackle environmental difficulties. Several physical and biological factors, such as animal motility, population densities, and chemical cues, play…

Biological Physics · Physics 2019-06-25 Esin Demir , Y. Ilker Yaman , Askin Kocabas

We analyse the neural dynamics and its relation with the emergent behaviour of a robotic vehicle that is controlled by a neural network numerical simulation based on the nervous system of the nematode Caenorhabditis elegans. The robot…

Neurons and Cognition · Quantitative Biology 2020-11-19 Carlos E. Valencia Urbina , Sergio A. Cannas , Pablo M. Gleiser

Animal behavior is often quantified through subjective, incomplete variables that may mask essential dynamics. Here, we develop a behavioral state space in which the full instantaneous state is smoothly unfolded as a combination of…

Neurons and Cognition · Quantitative Biology 2019-12-02 Tosif Ahamed , Antonio Carlos Costa , Greg J. Stephens

Caenorhabditis elegans, a free-living soil nematode, propels itself by producing undulatory body motion and displays a rich variety of body shapes and trajectories during its locomotion in complex environments. Here we show that the complex…

A major challenge in analyzing animal behavior is to discover some underlying simplicity in complex motor actions. Here we show that the space of shapes adopted by the nematode C. elegans is surprisingly low dimensional, with just four…

Other Quantitative Biology · Quantitative Biology 2016-01-05 Greg J Stephens , Bethany Johnson-Kerner , William Bialek , William S Ryu

An organism's ability to move freely is a fundamental behaviour in the animal kingdom. To understand animal locomotion requires a characterisation of the material properties, as well as the biomechanics and physiology. We present a…

Biological Physics · Physics 2017-02-17 Netta Cohen , Thomas Ranner

Neuromechanics aims to understand the link between an animal's neural activity and its physical behaviors. Recent advances in experimental and machine learning techniques enable simultaneous recordings of neural and locomotion dynamics over…

Biological Physics · Physics 2026-05-06 Alexander E. Cohen , Jörn Dunkel

We investigate how locomotory behavior is generated in the brain focusing on the paradigmatic connectome of nematode Caenorhabditis elegans (C. elegans) and on neuronal activity patterns that control forward locomotion. We map the neuronal…

Adaptation and Self-Organizing Systems · Physics 2020-06-17 Thomas Maertens , Eckehard Schöll , Jorge Ruiz , Philipp Hövel

{\it Caenorhabditis elegans} nematode worms are the only animals with the known detailed neural connectivity diagram, well characterized genomics, and relatively simple quantifiable behavioral output. With this in mind, many researchers…

Neurons and Cognition · Quantitative Biology 2019-10-17 Jan Karbowski

The design of amorphous entangled systems, specifically from soft and active materials, has the potential to open exciting new classes of active, shape-shifting, and task-capable 'smart' materials. However, the global emergent mechanics…

Soft Condensed Matter · Physics 2022-07-11 William Savoie , Harry Tuazon , M. Saad Bhamla , Daniel I. Goldman

Recent whole-brain calcium imaging recordings of the nematode C. elegans have demonstrated that neural activity is dominated by dynamics on a low-dimensional manifold that can be clustered according to behavioral states. Despite progress in…

Neurons and Cognition · Quantitative Biology 2020-02-05 Megan Morrison , Charles Fieseler , J. Nathan Kutz

We study external, electrical perturbations and their responses in the brain dynamic network of the \textit{Caenorhabditis elegans} soil worm, given by the connectome of its large somatic nervous system. Our analysis is inspired by a…

Neurons and Cognition · Quantitative Biology 2016-02-17 Chris G. Antonopoulos

Systems of active particles can show a large variety of collective behavior. In theory, two aspects determine the collective behavior: the model at the particle level and the parameter regime. While many studies consider a single model and…

Soft Condensed Matter · Physics 2025-11-17 Colin-Marius Koch , Michael Wilczek

Animal behaviors are sometimes decomposable into discrete, stereotyped elements. In one model, such behaviors are triggered by specific commands; in the extreme case, the discreteness of behavior is traced to the discreteness of action…

Neurons and Cognition · Quantitative Biology 2009-12-31 Greg J. Stephens , William S. Ryu , William Bialek

Biological circuits such as neural or gene regulation networks use internal states to map sensory input to an adaptive repertoire of behavior. Characterizing this mapping is a major challenge for systems biology, and though experiments that…

Neurons and Cognition · Quantitative Biology 2022-10-12 Edward D. Lee , Xiaowen Chen , Bryan C. Daniels

C. elegans locomotion is composed of switches between forward and reversal states punctuated by turns. This locomotory capability is necessary for the nematode to move towards attractive stimuli, escape noxious chemicals, and explore its…

Neurons and Cognition · Quantitative Biology 2025-01-03 Megan Morrison , Lai-Sang Young

The 1mm roundworm C. elegans is a model organism used in many sub-areas of biology to investigate different types of biological processes. In order to complement the n-vivo analysis with computer-based investigations, several methods have…

Quantitative Methods · Quantitative Biology 2025-10-02 Nemanja Antonic , Monika Scholz , Aymeric Vellinger , Euphrasie Ramahefarivo , Elio Tuci

Abrupt changes in behavior can often be associated with changes in underlying behavioral states. When placed off food, the foraging behavior of C. elegans can be described as a change between an initial local-search behavior characterized…

Neurons and Cognition · Quantitative Biology 2025-06-03 Andrew Margolis , Andrew Gordus

The nematode Caenorhabditis elegans is a well-known model organism used to investigate fundamental questions in biology. Motility assays of this small roundworm are designed to study the relationships between genes and behavior. Commonly,…

Computer Vision and Pattern Recognition · Computer Science 2015-05-19 Raphael Sznitman , Manaswi Gupta , Gregory D. Hager , Paulo E. Arratia , Josue Sznitman

Limbless locomotors, from microscopic worms to macroscopic snakes, traverse complex, heterogeneous natural environments typically using undulatory body wave propagation. Theoretical and robophysical models typically emphasize body…

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