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In recent years there has been great interest in using deep neural networks (DNN) for super-resolution image reconstruction including for structured illumination microscopy (SIM). While these methods have shown very promising results, they…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Zachary Burns , Zhaowei Liu

This work demonstrates a computational method for predicting the light propagation through a single multimode fiber using a deep neural network. The experiment for gathering training and testing data is performed with a digital micro-mirror…

Optics · Physics 2018-12-10 Pengfei Fan , Liang Deng , Lei Su

We show dense voxel embeddings learned via deep metric learning can be employed to produce a highly accurate segmentation of neurons from 3D electron microscopy images. A "metric graph" on a set of edges between voxels is constructed from…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Kisuk Lee , Ran Lu , Kyle Luther , H. Sebastian Seung

Sorting, filtering, moving and controlling colloidal particles is crucial in many fields, ranging from chemistry to biology and physics. Dielectrophoresis is an outstanding tool for the manipulation of small particles by AC electric fields,…

In the acquisition of Magnetic Resonance (MR) images shorter scan times lead to higher image noise. Therefore, automatic image denoising using deep learning methods is of high interest. MR images containing line-like structures such as…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Elisabeth Pfaehler , Daniel Pflugfelder , Hanno Scharr

Light microscopy is a widespread and inexpensive imaging technique facilitating biomedical discovery and diagnostics. However, light diffraction barrier and imperfections in optics limit the level of detail of the acquired images. The…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Gabriel della Maggiora , Vardan Andriasyan , Anthony Petkidis , Artsemi Yushkevich , Mikhail Kudryashev , Artur Yakimovich

Biologically-informed neural networks (BINNs), an extension of physics-informed neural networks [1], are introduced and used to discover the underlying dynamics of biological systems from sparse experimental data. In the present work, BINNs…

Quantitative Methods · Quantitative Biology 2021-01-27 John H. Lagergren , John T. Nardini , Ruth E. Baker , Matthew J. Simpson , Kevin B. Flores

Tracking of plant cells in images obtained by microscope is a challenging problem due to biological phenomena such as large number of cells, non-uniform growth of different layers of the tightly packed plant cells and cell division.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Md Shazid Islam , Arindam Dutta , Calvin-Khang Ta , Kevin Rodriguez , Christian Michael , Mark Alber , G. Venugopala Reddy , Amit K. Roy-Chowdhury

Recent SO(3)-equivariant models embedded a molecule as a set of single atoms fixed in the three-dimensional space, which is analogous to a ball-and-stick view. This perspective provides a concise view of atom arrangements, however, the…

Chemical Physics · Physics 2025-08-26 Bumju Kwak , Jeonghee Jo

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

Many physical systems are described by partial differential equations (PDEs), and solving these equations and estimating their coefficients or boundary conditions (BCs) from observational data play a crucial role in understanding the…

Machine Learning · Computer Science 2025-07-18 Tomohisa Okazaki

Particle-based shape modeling (PSM) is a popular approach to automatically quantify shape variability in populations of anatomies. The PSM family of methods employs optimization to automatically populate a dense set of corresponding…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Hong Xu , Shireen Y. Elhabian

Each photo in an image burst can be considered a sample of a complex 3D scene: the product of parallax, diffuse and specular materials, scene motion, and illuminant variation. While decomposing all of these effects from a stack of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-25 Ilya Chugunov , David Shustin , Ruyu Yan , Chenyang Lei , Felix Heide

Accurate brain parcellation in diffusion MRI (dMRI) space is essential for advanced neuroimaging analyses. However, most existing approaches rely on anatomical MRI for segmentation and inter-modality registration, a process that can…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Yousef Sadegheih , Dorit Merhof

The study of neurodegenerative diseases relies on the reconstruction and analysis of the brain cortex from magnetic resonance imaging (MRI). Traditional frameworks for this task like FreeSurfer demand lengthy runtimes, while its accelerated…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Rodrigo Santa Cruz , Leo Lebrat , Pierrick Bourgeat , Clinton Fookes , Jurgen Fripp , Olivier Salvado

Although physics-informed neural networks (PINNs) have shown great potential in dealing with nonlinear partial differential equations (PDEs), it is common that PINNs will suffer from the problem of insufficient precision or obtaining…

Machine Learning · Computer Science 2024-10-07 Feilong Jiang , Xiaonan Hou , Min Xia

In studying structural inter-connections in the human brain, it is common to first estimate fiber bundles connecting different regions of the brain relying on diffusion MRI. These fiber bundles act as highways for neural activity and…

Applications · Statistics 2016-12-06 Zhengwu Zhang , Maxime Descoteaux , David B. Dunson

Relying on either deep models or physical models are two mainstream approaches for solving inverse sample reconstruction problems in programmable illumination computational microscopy. Solutions based on physical models possess strong…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Ruiqing Sun , Delong Yang , Shaohui Zhang , Qun Hao

Light has many properties that vision sensors can passively measure. Colour-band separated wavelength and intensity are arguably the most commonly used for monocular 6D object pose estimation. This paper explores how complementary…

Computer Vision and Pattern Recognition · Computer Science 2022-07-14 Daoyi Gao , Yitong Li , Patrick Ruhkamp , Iuliia Skobleva , Magdalena Wysock , HyunJun Jung , Pengyuan Wang , Arturo Guridi , Benjamin Busam

Fluorescence polarization microscopy images both the intensity and orientation of fluorescent dipoles, which plays a vital role in studying the molecular structure and dynamics of bio-complex. However, it is difficult to resolve the dipole…

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