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Fiber orientation distribution (FOD) is an advanced diffusion MRI modeling technique that represents complex white matter fiber configurations, and a key step for subsequent brain tractography and connectome analysis. Its reliability and…

Tubular tree structures such as blood vessels and lung airways are central to many clinical tasks, including diagnosis, treatment planning, and surgical navigation. Accurate centerline extraction with correct topology is essential, as…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Roman Naeem , David Hagerman , Jennifer Alvén , Fredrik Kahl

Anatomical segmentation of organs in ultrasound images is essential to many clinical applications, particularly for diagnosis and monitoring. Existing deep neural networks require a large amount of labeled data for training in order to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yordanka Velikova , Mohammad Farid Azampour , Walter Simson , Vanessa Gonzalez Duque , Nassir Navab

Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs) that describe the distribution, direction, and volume of…

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

The interpretation of ligand-target interactions at atomistic resolution is central to most efforts in computational drug discovery and optimization. However, the highly dynamic nature of protein targets, as well as possible induced fit…

Biomolecules · Quantitative Biology 2024-12-04 Lara Callea , Camilla Caprai , Laura Bonati , Toni Giorgino , Stefano Motta

The first part of this paper ( arXiv:1607.02114 ) introduced splitting trees, those chronological trees admitting the self-similarity property where individuals give birth, at constant rate, to iid copies of themselves. It also established…

Probability · Mathematics 2025-04-01 Amaury Lambert , Gerónimo Uribe Bravo

Purpose: In diffusion MRI (dMRI), the volumetric and bundle analyses of whole-brain tissue microstructure and connectivity can be severely impeded by an incomplete field-of-view (FOV). This work aims to develop a method for imputing the…

Superficial white matter (SWM) has been less studied than long-range connections despite being of interest to clinical research, andfew tractography parcellation methods have been adapted to SWM. Here, we propose an efficient geometry-based…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Nabil Vindas , Nicole Labra Avila , Fan Zhang , Tengfei Xue , Lauren J. O'Donnell , Jean-François Mangin

White matter fiber clustering is an important strategy for white matter parcellation, which enables quantitative analysis of brain connections in health and disease. In combination with expert neuroanatomical labeling, data-driven white…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Yuqian Chen , Chaoyi Zhang , Tengfei Xue , Yang Song , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

This paper presents an automatic algorithm for the segmentation of areas affected by an acute stroke on the non-contrast computed tomography brain images. The proposed algorithm is designed for learning in a weakly supervised scenario when…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Anna Dobshik , Andrey Tulupov , Vladimir Berikov

Trace clustering has increasingly been applied to find homogenous process executions. However, current techniques have difficulties in finding a meaningful and insightful clustering of patients on the basis of healthcare data. The resulting…

Databases · Computer Science 2020-01-13 Xixi Lu , Seyed Amin Tabatabaei , Mark Hoogendoorn , Hajo A. Reijers

Deep learning-based segmentation techniques have shown remarkable performance in brain segmentation, yet their success hinges on the availability of extensive labeled training data. Acquiring such vast datasets, however, poses a significant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Jihoon Cho , Suhyun Ahn , Beomju Kim , Hyungjoon Bae , Xiaofeng Liu , Fangxu Xing , Kyungeun Lee , Georges Elfakhri , Van Wedeen , Jonghye Woo , Jinah Park

The white matter of the brain is organised into axonal bundles that support long-range neural communication. Although diffusion MRI (dMRI) enables detailed mapping of these pathways through tractography, how white matter pathways directly…

Neurons and Cognition · Quantitative Biology 2026-02-24 Yifei Sun , James M. Shine , Robert D. Sanders , Robin F. H. Cash , Sharon L. Naismith , Fernando Calamante , Jinglei Lv

Blood vessel segmentation and -tracing are essential tasks in many medical imaging applications. Although numerous methods exist, the prevailing segment-then-fix paradigm is fundamentally limited regarding its suitability for modeling the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Rajalakshmi Palaniappan , Christoph Karg , Nemesio Navarro-Arambula , Peter Hirsch , Kristin Kraeker , Lisa Mais , Dagmar Kainmueller

Medical imaging datasets often contain heterogeneous biases ranging from erroneous labels to inconsistent labeling styles. Such biases can negatively impact deep segmentation networks performance. Yet, the identification and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Samuel Joutard , Marijn Stollenga , Marc Balle Sanchez , Mohammad Farid Azampour , Raphael Prevost

Spectral clustering is a leading clustering method. Two of its major shortcomings are the disjoint optimization process and the limited representation capacity. To address these issues, we propose a deep spectral clustering model (named…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Wengang Guo , Wei Ye , Chunchun Chen , Xin Sun , Christian Böhm , Claudia Plant , Susanto Rahardja

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

This study details the development and validation of a new algorithm that determines the dominant habit plane of a transformed child phase from orientation maps of a single planar cross-section. The method describes the habit plane in terms…

Materials Science · Physics 2023-03-15 Tuomo Nyyssonen , Azdiar A. Gazder , Ralf Hielscher , Frank Niessen

The thalamus consists of several histologically and functionally distinct nuclei increasingly implicated in brain pathology and important for treatment, motivating the need for development of fast and accurate thalamic segmentation. The…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Charles Iglehart , Martin Monti , Joshua Cain , Thomas Tourdias , Manojkumar Saranathan