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The segmentation of cranial nerves (CNs) tract provides a valuable quantitative tool for the analysis of the morphology and trajectory of individual CNs. Multimodal CNs tract segmentation networks, e.g., CNTSeg, which combine structural…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Lei Xie , Huajun Zhou , Junxiong Huang , Jiahao Huang , Qingrun Zeng , Jianzhong He , Jiawei Zhang , Baohua Fan , Mingchu Li , Guoqiang Xie , Hao Chen , Yuanjing Feng

In this paper, we present a flexible and probabilistic framework for tracking topological features in time-varying scalar fields using merge trees and partial optimal transport. Merge trees are topological descriptors that record the…

Computational Geometry · Computer Science 2025-08-26 Mingzhe Li , Xinyuan Yan , Lin Yan , Tom Needham , Bei Wang

The purpose of this work is to develop a framework for single-subject analysis of diffusion tensor imaging (DTI) data. This framework (termed TOADDI) is capable of testing whether an individual tract as represented by the major eigenvector…

Due to imaging artifacts and low signal-to-noise ratio in ultrasound images, automatic bone surface segmentation networks often produce fragmented predictions that can hinder the success of ultrasound-guided computer-assisted surgical…

Image and Video Processing · Electrical Eng. & Systems 2022-06-20 Aimon Rahman , Wele Gedara Chaminda Bandara , Jeya Maria Jose Valanarasu , Ilker Hacihaliloglu , Vishal M Patel

Motivated by the increasing availability of vehicle trajectory data, we propose learn-to-route, a comprehensive trajectory-based routing solution. Specifically, we first construct a graph-like structure from trajectories as the routing…

Machine Learning · Computer Science 2018-02-23 Chenjuan Guo , Bin Yang , Jilin Hu , Christian S. Jensen

Proteins play a critical role in carrying out biological functions, and their 3D structures are essential in determining their functions. Accurately predicting the conformation of protein side-chains given their backbones is important for…

Quantitative Methods · Quantitative Biology 2024-02-19 Yangtian Zhang , Zuobai Zhang , Bozitao Zhong , Sanchit Misra , Jian Tang

Neuroscientific data analysis has traditionally relied on linear algebra and stochastic process theory. However, the tree-like shapes of neurons cannot be described easily as points in a vector space (the subtraction of two neuronal shapes…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Dingkang Wang , Lucas Magee , Bing-Xing Huo , Samik Banerjee , Xu Li , Jaikishan Jayakumar , Meng Kuan Lin , Keerthi Ram , Suyi Wang , Yusu Wang , Partha P. Mitra

The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…

Methodology · Statistics 2022-11-03 Didong Li , Phuc Nguyen , Zhengwu Zhang , David B Dunson

We present a novel method for estimation of the fiber orientation distribution (FOD) function based on diffusion-weighted Magnetic Resonance Imaging (D-MRI) data. We formulate the problem of FOD estimation as a regression problem through…

Applications · Statistics 2016-12-23 Hao Yan , Owen Carmichael , Debashis Paul , Jie Peng

Shape measures have emerged as promising descriptors of white matter tractography, offering complementary insights into anatomical variability and associations with cognitive and clinical phenotypes. However, conventional methods for…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Yui Lo , Yuqian Chen , Dongnan Liu , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Fan Zhang , Weidong Cai , Lauren J. O'Donnell

Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and non-invasive manner through measuring water diffusion. The contribution of this paper is…

We present a braided circuit topology framework for investigating topology and structural phase transitions in aggregates of semiflexible polymers. In the conventional approach to circuit topology, which specifically applies to single…

Soft Condensed Matter · Physics 2024-02-27 Jonas Berx , Alireza Mashaghi

Human skill learning requires fine-scale coordination of distributed networks of brain regions that are directly linked to one another by white matter tracts to allow for effective information transmission. Yet how individual differences in…

Neurons and Cognition · Quantitative Biology 2016-10-25 Ari E. Kahn , Marcelo G. Mattar , Jean M. Vettel , Nicholas F. Wymbs , Scott T. Grafton , Danielle S. Bassett

Diffusion MRI (dMRI) provides a distinctive means to probe the microstructural architecture of living tissue, facilitating applications such as brain connectivity analysis, modeling across multiple conditions, and the estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Jongyeon Yoon , Elyssa M. McMaster , Michael E. Kim , Gaurav Rudravaram , Kurt G. Schilling , Bennett A. Landman , Daniel Moyer

This paper describes the adaptation of a well-scaling parallel algorithm for computing Morse-Smale segmentations based on path compression to a distributed computational setting. Additionally, we extend the algorithm to efficiently compute…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-09-09 Michael Will , Jonas Lukasczyk , Julien Tierny , Christoph Garth

Diffusion Tensor Imaging (DTI) is a non-invasive imaging technique that allows estimation of the location of white matter tracts in-vivo, based on the measurement of water diffusion properties. For each voxel, a second-order tensor can be…

Computer Vision and Pattern Recognition · Computer Science 2013-10-24 Miriam H. A. Bauer , Sebastiano Barbieri , Jan Klein , Jan Egger , Daniela Kuhnt , Bernd Freisleben , Horst K. Hahn , Christopher Nimsky

Convolution plays a crucial role in various applications in signal and image processing, analysis, and recognition. It is also the main building block of convolution neural networks (CNNs). Designing appropriate convolution neural networks…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Pengfei Jin , Tianhao Lai , Rongjie Lai , Bin Dong

Topo-Tomography (TT) is a synchrotron-based X-ray diffraction imaging technique used to characterize grain shape and crystal orientation in polycrystalline samples. This work aims to provide a decisive and fundamental understanding of 3D…

Computational Physics · Physics 2025-10-13 Zheheng Liu , Nicola Vigano , Henry Proudhon , Wolfgang Ludwig

The morphology and hierarchy of the vascular systems are essential for perfusion in supporting metabolism. In human retina, one of the most energy-demanding organs, retinal circulation nourishes the entire inner retina by an intricate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Siyi Chen , Amir H. Kashani , Ji Yi

We present a flexible method for computing Bayesian optimal experimental designs (BOEDs) for inverse problems with intractable posteriors. The approach is applicable to a wide range of BOED problems and can accommodate various optimality…

Computation · Statistics 2024-08-20 Karina Koval , Roland Herzog , Robert Scheichl
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