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The maximum mean discrepancy (MMD) is a kernel-based distance between probability distributions useful in many applications (Gretton et al. 2012), bearing a simple estimator with pleasing computational and statistical properties. Being able…

Machine Learning · Statistics 2022-11-16 Danica J. Sutherland , Namrata Deka

Cohort studies employ pairwise measures of association to quantify dependencies among conditions and exposures. To reliably use these measures to draw conclusions about the underlying association strengths requires that the measures be…

Quantitative Methods · Quantitative Biology 2017-05-30 Venkateshan Kannan , Kristina Alexandersson , Jesper Tegner

One of the formulations of Heisenberg uncertainty principle, concerning so-called measurement uncertainty, states that the measurement of one observable modifies the statistics of the other. Here, we derive such a measurement uncertainty…

Size distortion can occur if an asymptotic testing procedure requiring diverging sample sizes, is implemented to data with very small sample sizes. In this paper, we consider one-sample and two-sample tests for mean vectors when data are…

Methodology · Statistics 2022-03-17 Jun Li

This paper studies the Hardy-type inequalities on the discrete intervals. The first result is the variational formulas of the optimal constants. Using these formulas, one may obtain an approximating procedure and the known basic estimates…

Functional Analysis · Mathematics 2014-06-24 Zhong-Wei Liao

Measurement error is a pervasive challenge across many disciplines, yet its impact on sample size determination and the accuracy and precision of estimators regarding the association between an exposure and an outcome remains understudied…

Methodology · Statistics 2025-05-27 Honghyok Kim

Double blind randomized controlled trials are traditionally seen as the gold standard for causal inferences as the difference-in-means estimator is an unbiased estimator of the average treatment effect in the experiment. The fact that this…

Methodology · Statistics 2021-08-25 Per Johansson , Mattias Nordin

In our chapter we address the statistical analysis of percentiles: How should the citation impact of institutions be compared? In educational and psychological testing, percentiles are already used widely as a standard to evaluate an…

Digital Libraries · Computer Science 2014-04-16 Richard Williams , Lutz Bornmann

We test against two different sets of data an apparently new approach to the analysis of the variance of a numerical variable which depends on qualitative characters. We suggest that this approach be used to complement other existing…

Bayes factors represent the ratio of probabilities assigned to data by competing scientific hypotheses. Drawbacks of Bayes factors are their dependence on prior specifications that define null and alternative hypotheses and difficulties…

Statistics Theory · Mathematics 2023-03-29 Valen E. Johnson , Sandipan Pramanik , Rachael Shudde

We propose the use of a simple intuitive principle for measuring algorithmic classification bias: the significance of the differences in a classifier's error rates across the various demographics is inversely commensurate with the sample…

Methodology · Statistics 2026-01-08 Ioannis Ivrissimtzis , Shauna Concannon , Matthew Houliston , Graham Roberts

Due to their heterogeneity, insurance risks can be properly described as a mixture of different fixed models, where the weights assigned to each model may be estimated empirically from a sample of available data. If a risk measure is…

Risk Management · Quantitative Finance 2018-02-12 Valeria Bignozzi , Claudio Macci , Lea Petrella

Contemporary statistical publications rely on simulation to evaluate performance of new methods and compare them with established methods. In the context of meta-analysis of log-odds-ratios, we investigate how the ways in which simulations…

Methodology · Statistics 2020-07-06 Elena Kulinskaya , David C. Hoaglin , Ilyas Bakbergenuly

In systematic reviews and meta-analysis, researchers often pool the results of the sample mean and standard deviation from a set of similar clinical trials. A number of the trials, however, reported the study using the median, the minimum…

Methodology · Statistics 2016-10-06 Xiang Wan , Wenqian Wang , Jiming Liu , Tiejun Tong

Based on the median and the median absolute deviation estimators, and the Hodges-Lehmann and Shamos estimators, robustified analogues of the conventional $t$-test statistic are proposed. The asymptotic distributions of these statistics are…

Applications · Statistics 2022-02-24 Chanseok Park , Min Wang

Linear mixed-effects models are widely used in analyzing repeated measures data, including clustered and longitudinal data, where inferences of both fixed effects and variance components are of importance. Unlike the fixed effect inference…

Methodology · Statistics 2022-08-31 J. Zhang , W. Guo , J. S. Carpenter , Andrew Leroux , K. R. Merikangas , N. G. Martin , I. B. Hickie , H. Shou , H. Li

A coefficient is introduced that quantifies the extent of separation of a random variable $Y$ relative to a number of variables $\mathbf{X} = (X_1, \dots, X_p)$ by skillfully assessing the sensitivity of the relative effects of the…

Methodology · Statistics 2025-03-27 Sebastian Fuchs , Carsten Limbach , Patrick B. Langthaler

In cell biology, statistical analysis means testing the hypothesis that there was no effect. This weak form of hypothesis testing neglects effect size, is universally misinterpreted, and is disastrously prone to error when combined with…

Other Quantitative Biology · Quantitative Biology 2025-05-13 Josh L. Morgan

The celebrated Hardy inequality can be written in the form $$\int_0^\infty \mathcal{P}_p \big(f|_{[0,x]}\big)dx \le (1-p)^{-1/p} \int_0^\infty f(x)\:dx \qquad \text{ for }p\in(0,1)\text{ and }f \in L^1\text{ with }f\ge0,$$ where…

Classical Analysis and ODEs · Mathematics 2022-06-29 Paweł Pasteczka

Testing effect size homogeneity is an essential part when conducting a meta-analysis. Comparative studies of effect size homogeneity tests in case of binary outcomes are found in the literature, but no test has come out as an absolute…

Methodology · Statistics 2022-03-11 Osama Almalik