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We propose an optimal algorithm for estimating conditional average treatment effects (CATEs) when response functions lie in a reproducing kernel Hilbert space (RKHS). We study settings in which the contrast function is structurally simpler…

Methodology · Statistics 2026-02-25 Seok-Jin Kim

This R package evaluates main and pair-wise interaction effect of single nucleotide polymorphisms (SNPs) via the W-test, scalable to whole genome-wide data sets. The package provides fast and accurate p-value estimation of genetic markers,…

Computation · Statistics 2016-10-12 Rui Sun , Billy Chang , Benny Chung-Ying Zee , Maggie Haitian Wang

Multivariate interaction between two or more classes (or species) has important consequences in many fields and causes multivariate clustering patterns such as segregation or association. The spatial segregation occurs when members of a…

Methodology · Statistics 2008-05-13 Elvan Ceyhan

Stepped wedge cluster randomized trials (SW-CRTs) have become increasingly popular and are used for a variety of interventions and outcomes, often chosen for their feasibility advantages. SW-CRTs must account for time trends in the outcome…

Methodology · Statistics 2024-07-16 Lee Kennedy-Shaffer , Victor De Gruttola , Marc Lipsitch

Support vector machines (SVMs) are special kernel based methods and belong to the most successful learning methods since more than a decade. SVMs can informally be described as a kind of regularized M-estimators for functions and have…

Machine Learning · Statistics 2010-07-26 Andreas Christmann , Robert Hable

Recently, there has been a significant growth of interest in applying software engineering techniques for the quality assurance of deep learning (DL) systems. One popular direction is deep learning testing, where adversarial examples…

Software Engineering · Computer Science 2021-02-16 Jingyi Wang , Jialuo Chen , Youcheng Sun , Xingjun Ma , Dongxia Wang , Jun Sun , Peng Cheng

Despite excellent performance on many tasks, NLP systems are easily fooled by small adversarial perturbations of inputs. Existing procedures to defend against such perturbations are either (i) heuristic in nature and susceptible to stronger…

Computation and Language · Computer Science 2020-05-05 Erik Jones , Robin Jia , Aditi Raghunathan , Percy Liang

Spurious correlations pose a major challenge for robust machine learning. Models trained with empirical risk minimization (ERM) may learn to rely on correlations between class labels and spurious attributes, leading to poor performance on…

Machine Learning · Computer Science 2024-12-12 Michael Zhang , Nimit S. Sohoni , Hongyang R. Zhang , Chelsea Finn , Christopher Ré

We introduce CARETS, a systematic test suite to measure consistency and robustness of modern VQA models through a series of six fine-grained capability tests. In contrast to existing VQA test sets, CARETS features balanced question…

Computation and Language · Computer Science 2022-03-16 Carlos E. Jimenez , Olga Russakovsky , Karthik Narasimhan

Maintaining the quality of manufactured products at a desired level is known to increase customer satisfaction and profitability. Shewhart control chart is the most widely used in statistical process control (SPC) technique to monitor the…

Other Statistics · Statistics 2018-12-31 Burak Alakent , Ece C. Mutlu

We propose a new one-sample test for normality in a Reproducing Kernel Hilbert Space (RKHS). Namely, we test the null-hypothesis of belonging to a given family of Gaussian distributions. Hence our procedure may be applied either to test…

Statistics Theory · Mathematics 2015-07-13 Jérémie Kellner , Alain Celisse

Spatial extent inference (SEI) is widely used across neuroimaging modalities to study brain-phenotype associations that inform our understanding of disease. Recent studies have shown that Gaussian random field (GRF) based tools can have…

Regression neural networks (NNs) are most commonly trained by minimizing the mean squared prediction error, which is highly sensitive to outliers and data contamination. Existing robust training methods for regression NNs are often limited…

Machine Learning · Statistics 2026-02-10 Abhik Ghosh , Suryasis Jana

Robustness has been extensively studied in reinforcement learning (RL) to handle various forms of uncertainty such as random perturbations, rare events, and malicious attacks. In this work, we consider one critical type of robustness…

Machine Learning · Computer Science 2023-10-27 Wenhao Ding , Laixi Shi , Yuejie Chi , Ding Zhao

Background: Identification of causal SNPs in most genome wide association studies relies on approaches that consider each SNP individually. However, there is a strong correlation structure among SNPs that need to be taken into account.…

Applications · Statistics 2012-11-02 Verena Zuber , A. Pedro Duarte Silva , Korbinian Strimmer

The problem of robust binary hypothesis testing is studied. Under both hypotheses, the data-generating distributions are assumed to belong to uncertainty sets constructed through moments; in particular, the sets contain distributions whose…

Statistics Theory · Mathematics 2024-01-09 Akshayaa Magesh , Zhongchang Sun , Venugopal V. Veeravalli , Shaofeng Zou

In this work, we show that Spearman's correlation coefficient test about $H_0:\rho_s=0$ found in most statistical software packages is theoretically incorrect and performs poorly when bivariate normality assumptions are not met or the…

Methodology · Statistics 2020-08-05 Han Yu , Alan D. Hutson

Kernel-based multi-marker tests for survival outcomes use primarily the Cox model to adjust for covariates. The proportional hazards assumption made by the Cox model could be unrealistic, especially in the long-term follow-up. We develop a…

Methodology · Statistics 2024-01-19 Chenxi Li , Di Wu , Qing Lu

Ryabinkin-Kohut-Staroverov (RKS) theory builds a bridge between wave function theory and density functional theory by using quantities from the former to produce accurate exchange-correlation potentials needed by the latter. In this work,…

Chemical Physics · Physics 2023-08-16 Soumi Tribedi , Duy-Khoi Dang , Bikash Kanungo , Vikram Gavini , Paul M. Zimmerman

Harmonization methods such as ComBat and its variants are widely used to mitigate diffusion MRI (dMRI) site-specific biases. However, ComBat assumes that subject distributions exhibit a Gaussian profile. In practice, patients with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Yoan David , Pierre-Marc Jodoin , Alzheimer's Disease Neuroimaging Initiative , The TRACK-TBI Investigators