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In this paper, we present a novel automated method for White Matter (WM) lesion segmentation of Multiple Sclerosis (MS) patient images. Our approach is based on a cascade of two 3D patch-wise convolutional neural networks (CNN). The first…

Accurate segmentation of skin lesions within dermoscopic images plays a crucial role in the timely identification of skin cancer for computer-aided diagnosis on mobile platforms. However, varying shapes of the lesions, lack of defined…

Lesion segmentation on computed tomography (CT) scans is an important step for precisely monitoring changes in lesion/tumor growth. This task, however, is very challenging since manual segmentation is prohibitively time-consuming,…

The spinal cord is frequently affected by atrophy and/or lesions in multiple sclerosis (MS) patients. Segmentation of the spinal cord and lesions from MRI data provides measures of damage, which are key criteria for the diagnosis,…

With a large influx of dermoscopy images and a growing shortage of dermatologists, automatic dermoscopic image analysis plays an essential role in skin cancer diagnosis. In this paper, a new deep fully convolutional neural network (FCNN) is…

Melanoma is amongst most aggressive types of cancer. However, it is highly curable if detected in its early stages. Prescreening of suspicious moles and lesions for malignancy is of great importance. Detection can be done by images captured…

Semantic image segmentation is one of the most important tasks in medical image analysis. Most state-of-the-art deep learning methods require a large number of accurately annotated examples for model training. However, accurate annotation…

Deep learning (DL) networks have recently been shown to outperform other segmentation methods on various public, medical-image challenge datasets [3,11,16], especially for large pathologies. However, in the context of diseases such as…

Segmenting healthy tissue structures alongside lesions in brain Magnetic Resonance Images (MRI) remains a challenge for today's algorithms due to lesion-caused disruption of the anatomy and lack of jointly labeled training datasets, where…

Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of…

Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

The automated detection of cortical lesions (CLs) in patients with multiple sclerosis (MS) is a challenging task that, despite its clinical relevance, has received very little attention. Accurate detection of the small and scarce lesions…

Deep convolutional neural networks have driven substantial advancements in the automatic understanding of images. Requiring a large collection of images and their associated annotations is one of the main bottlenecks limiting the adoption…

Deep learning implemented with convolutional network architectures can exceed specialists' diagnostic accuracy. However, whole-image deep learning trained on a given dataset may not generalize to other datasets. The problem arises because…

Melanoma is clinically difficult to distinguish from common benign skin lesions, particularly melanocytic naevus and seborrhoeic keratosis. The dermoscopic appearance of these lesions has huge intra-class variations and high inter-class…

Automatic segmentation of skin lesion is considered a crucial step in Computer Aided Diagnosis (CAD) for melanoma diagnosis. Despite its significance, skin lesion segmentation remains a challenging task due to their diverse color, texture,…

Since the rise of deep learning, many computer vision tasks have seen significant advancements. However, the downside of deep learning is that it is very data-hungry. Especially for segmentation problems, training a deep neural net requires…

Computer-aided diagnosis systems for classification of different type of skin lesions have been an active field of research in recent decades. It has been shown that introducing lesions and their attributes masks into lesion classification…

Deep neural networks have demonstrated exceptional efficacy in stroke lesion segmentation. However, the delineation of small lesions, critical for stroke diagnosis, remains a challenge. In this study, we propose two straightforward yet…

In recent years, several convolutional neural network (CNN) methods have been proposed for the automated white matter lesion segmentation of multiple sclerosis (MS) patient images, due to their superior performance compared with those of…