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Uncertainty quantification for individual treatment effects (ITEs) is a daunting challenge in causal inference. Motivated by recent advances in conformal prediction, several works aim to construct distribution-free prediction sets for ITEs…

Methodology · Statistics 2026-05-07 Chongguang Tao , Zheng Zhou , Yuhong Yang

Meta-analysis is commonly used to combine results from multiple clinical trials, but traditional meta-analysis methods do not refer explicitly to a population of individuals to whom the results apply and it is not clear how to use their…

Causal inference has received great attention across different fields from economics, statistics, education, medicine, to machine learning. Within this area, inferring causal effects at individual level in observational studies has become…

Methodology · Statistics 2017-02-16 Thai Pham

Causal inference is capable of estimating the treatment effect (i.e., the causal effect of treatment on the outcome) to benefit the decision making in various domains. One fundamental challenge in this research is that the treatment…

Machine Learning · Computer Science 2021-12-28 Qian Li , Zhichao Wang , Shaowu Liu , Gang Li , Guandong Xu

Interpretable representations are the backbone of many explainers that target black-box predictive systems based on artificial intelligence and machine learning algorithms. They translate the low-level data representation necessary for good…

Machine Learning · Computer Science 2024-04-29 Kacper Sokol , Peter Flach

Machine learning models that offer excellent predictive performance often lack the interpretability necessary to support integrated human machine decision-making. In clinical medicine and other high-risk settings, domain experts may be…

Machine Learning · Computer Science 2021-04-19 Zach Wood-Doughty , Isabel Cachola , Mark Dredze

Intervention intuition is often used in model explanation where the intervention effect of a feature on the outcome is quantified by the difference of a model prediction when the feature value is changed from the current value to the…

Machine Learning · Computer Science 2024-10-22 Debo Cheng , Ziqi Xu , Jiuyong Li , Lin Liu , Kui Yu , Thuc Duy Le , Jixue Liu

The popularity of machine learning has increased the risk of unfair models getting deployed in high-stake applications, such as justice system, drug/vaccination design, and medical diagnosis. Although there are effective methods to train…

Machine Learning · Computer Science 2022-07-14 Mohit Bajaj , Lingyang Chu , Vittorio Romaniello , Gursimran Singh , Jian Pei , Zirui Zhou , Lanjun Wang , Yong Zhang

Causal inference from observational data requires untestable identification assumptions. If these assumptions apply, machine learning (ML) methods can be used to study complex forms of causal effect heterogeneity. Recently, several ML…

Methodology · Statistics 2023-12-20 Richard Post , Isabel van den Heuvel , Marko Petkovic , Edwin van den Heuvel

In human-centric settings like education or healthcare, model accuracy and model explainability are key factors for user adoption. Towards these two goals, intrinsically interpretable deep learning models have gained popularity, focusing on…

Machine Learning · Computer Science 2025-05-29 Vinitra Swamy , Syrielle Montariol , Julian Blackwell , Jibril Frej , Martin Jaggi , Tanja Käser

In an era where diverse and complex data are increasingly accessible, the precise prediction of individual treatment effects (ITE) becomes crucial across fields such as healthcare, economics, and public policy. Current state-of-the-art…

Machine Learning · Statistics 2025-01-28 Baozhen Wang , Xingye Qiao

In many settings, it is important that a model be capable of providing reasons for its predictions (i.e., the model must be interpretable). However, the model's reasoning may not conform with well-established knowledge. In such cases, while…

Machine Learning · Computer Science 2019-02-19 Jiaxuan Wang , Jeeheh Oh , Haozhu Wang , Jenna Wiens

We present a brief history of the field of interpretable machine learning (IML), give an overview of state-of-the-art interpretation methods, and discuss challenges. Research in IML has boomed in recent years. As young as the field is, it…

Machine Learning · Statistics 2022-01-24 Christoph Molnar , Giuseppe Casalicchio , Bernd Bischl

Machine learning (ML) interpretability techniques can reveal undesirable patterns in data that models exploit to make predictions--potentially causing harms once deployed. However, how to take action to address these patterns is not always…

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Understanding the predictions made by deep learning models remains a central challenge, especially in high-stakes applications. A promising approach is to equip models with the ability to answer counterfactual questions -- hypothetical…

Machine Learning · Computer Science 2025-10-28 Inwoo Hwang , Yushu Pan , Elias Bareinboim

Understanding why machine learning models behave the way they do empowers both system designers and end-users in many ways: in model selection, feature engineering, in order to trust and act upon the predictions, and in more intuitive user…

Machine Learning · Statistics 2016-06-20 Marco Tulio Ribeiro , Sameer Singh , Carlos Guestrin

Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

Machine Learning · Statistics 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara

Mechanistic Interpretability aims to understand neural networks through causal explanations. We argue for the Explanatory View Hypothesis: that Mechanistic Interpretability research is a principled approach to understanding models because…

Machine Learning · Computer Science 2025-05-05 Kola Ayonrinde , Louis Jaburi

Transparency, user trust, and human comprehension are popular ethical motivations for interpretable machine learning. In support of these goals, researchers evaluate model explanation performance using humans and real world applications.…

Artificial Intelligence · Computer Science 2019-10-31 Bernease Herman
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