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Optical coherence tomography angiography (OCTA) is an imaging technique that allows for non-invasive investigation of the microvasculature in the retina. OCTA uses laser light reflectance to measure moving blood cells. Hereby, it visualizes…

Tissues and Organs · Quantitative Biology 2020-02-11 Astrid M. E. Engberg , Vedrana A. Dahl , Anders B. Dahl

One-shot image generation (OSG) with generative adversarial networks that learn from the internal patches of a given image has attracted world wide attention. In recent studies, scholars have primarily focused on extracting features of…

Computer Vision and Pattern Recognition · Computer Science 2023-02-17 Yunliang Jiang , Lili Yan , Xiongtao Zhang , Yong Liu , Danfeng Sun

We present a deep learning framework for volumetric speckle reduction in optical coherence tomography (OCT) based on a conditional generative adversarial network (cGAN) that leverages the volumetric nature of OCT data. In order to utilize…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Bhaskara Rao Chintada , Sebastián Ruiz-Lopera , René Restrepo , Brett E. Bouma , Martin Villiger , Néstor Uribe-Patarroyo

Endoscopic optical coherence tomography (OCT) is a valuable tool for providing diagnostic images of internal organs and guiding interventions in real time. Miniaturized OCT endoscopes are essential for imaging small and convoluted luminal…

Instrumentation and Detectors · Physics 2023-11-28 Chao Xu , Xin Guan , Syeda Aimen Abbasi , Neng Xia , To Ngai , Li Zhang , Ho-Pui Ho , Sze Hang Calvin Ng , Wu Yuan

Retinal fundus photographs have been used in the diagnosis of many ocular diseases such as glaucoma, pathological myopia, age-related macular degeneration and diabetic retinopathy. With the development of computer science, computer aided…

Computer Vision and Pattern Recognition · Computer Science 2018-11-02 Jun Cheng , Zhengguo Li , Zaiwang Gu , Huazhu Fu , Damon Wing Kee Wong , Jiang Liu

Transformers are very powerful tools for a variety of tasks across domains, from text generation to image captioning. However, transformers require substantial amounts of training data, which is often a challenge in biomedical settings,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Andrew Kean Gao

Optical Coherence Tomography (OCT) is the primary imaging modality for detecting pathological biomarkers associated to retinal diseases such as Age-Related Macular Degeneration. In practice, clinical diagnosis and treatment strategies are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Thomas Kurmann , Pablo Márquez-Neila , Siqing Yu , Marion Munk , Sebastian Wolf , Raphael Sznitman

We report, to our knowledge, the first end-to-end application of Generative Adversarial Networks (GANs) towards the synthesis of Optical Coherence Tomography (OCT) images of the retina. Generative models have gained recent attention for the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-19 Stephen G. Odaibo , M. D. , M. S. , M. S.

Exudative (wet) age-related macular degeneration (AMD) is a leading cause of vision loss in older adults, typically treated with intravitreal injections. Emerging therapies, such as subretinal injections of stem cells, gene therapy, small…

Quantification of intra-retinal boundaries in optical coherence tomography (OCT) is a crucial task for studying and diagnosing neurological and ocular diseases. Since manual segmentation of layers is usually a time consuming task and relay…

Computer Vision and Pattern Recognition · Computer Science 2015-02-17 Mahdi Salarian

Despite the astonishing performance of deep-learning based approaches for visual tasks such as semantic segmentation, they are known to produce miscalibrated predictions, which could be harmful for critical decision-making processes.…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Agostina J. Larrazabal , César Martínez , Jose Dolz , Enzo Ferrante

Given the capacity of Optical Coherence Tomography (OCT) imaging to display symptoms of a wide variety of eye diseases and neurological disorders, the need for OCT image segmentation and the corresponding data interpretation is latterly…

With the introduction of spectral-domain optical coherence tomography (SDOCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, there is a critical need…

Computer Vision and Pattern Recognition · Computer Science 2015-08-06 Yankui Sun , Tian Zhang , Yue Zhao , Yufan He

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Inverse scattering in optical coherence tomography (OCT) seeks to recover both structural images and intrinsic tissue optical properties, including refractive index, scattering coefficient, and anisotropy. This inverse problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Jinglun Yu , Yaning Wang , Wenhan Guo , Yuan Gao , Yu Sun , Jin U. Kang

Recently, deep learning approaches have been extensively studied for low-dose CT denoising thanks to its superior performance despite the fast computational time. In particular, cycleGAN has been demonstrated as a powerful unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2020-08-14 Jawook Gu , Jong Chul Ye

Glaucoma is one of the leading causes of blindness worldwide and Optical Coherence Tomography (OCT) is the quintessential imaging technique for its detection. Unlike most of the state-of-the-art studies focused on glaucoma detection, in…

Image and Video Processing · Electrical Eng. & Systems 2021-06-28 Gabriel García , Rocío del Amor , Adrián Colomer , Rafael Verdú-Monedero , Juan Morales-Sánchez , Valery Naranjo

Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique widely used to study vascular structures and micro-circulation dynamics in the retina and choroid. OCTA has been widely used in clinics for diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Kejie Chen , Guanbing Gao , Xiaochun Yang , Wenbo Wang , Jing Na

3D imaging modalities are becoming increasingly popular and relevant in retinal imaging owing to their effectiveness in highlighting structures in sub-retinal layers. OCT is one such modality which has great importance in the context of…

Computer Vision and Pattern Recognition · Computer Science 2016-12-09 Karthik Gopinath , Jayanthi Sivaswamy

We cast the problem of image denoising as a domain translation problem between high and low noise domains. By modifying the cycleGAN model, we are able to learn a mapping between these domains on unpaired retinal optical coherence…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Ilja Manakov , Markus Rohm , Christoph Kern , Benedikt Schworm , Karsten Kortuem , Volker Tresp