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This paper introduces a novel statistical framework for independent component analysis (ICA) of multivariate data. We propose methodology for estimating and testing the existence of mutually independent components for a given dataset, and a…

Methodology · Statistics 2013-06-21 David S. Matteson , Ruey S. Tsay

Independent component analysis (ICA) is a computational method for separating a multivariate signal into subcomponents assuming the mutual statistical independence of the non-Gaussian source signals. The classical Independent Components…

Information Theory · Computer Science 2015-05-19 Huy Nguyen , Rong Zheng

An asynchronous Brain--Computer Interface (BCI) based on imagined speech is a tool that allows to control an external device or to emit a message at the moment the user desires to by decoding EEG signals of imagined speech. In order to…

Human-Computer Interaction · Computer Science 2021-05-11 Tonatiuh Hernández-Del-Toro , Carlos A. Reyes-García , Luis Villaseñor-Pineda

A limiting factor towards the wide routine use of wearables devices for continuous healthcare monitoring is their cumbersome and obtrusive nature. This is particularly true for electroencephalography (EEG) recordings, which require the…

Signal Processing · Electrical Eng. & Systems 2021-05-20 Laura M. Ferrari , Guy Abi Hanna , Paolo Volpe , Esma Ismailova , François Bremond , Maria A. Zuluaga

In recent years, longitudinal neuroimaging study has become increasingly popular in neuroscience research to investigate disease-related changes in brain functions. In current neuroscience literature, one of the most commonly used tools to…

Methodology · Statistics 2018-08-07 Yikai Wang , Ying Guo

This thesis delves into the world of non-invasive electrophysiological brain signals like electroencephalography (EEG) and magnetoencephalography (MEG), focusing on modelling and decoding such data. The research aims to investigate what…

Signal Processing · Electrical Eng. & Systems 2025-10-30 Richard Csaky

The electrocardiogram (ECG) is the gold standard for non-invasive diagnosis of cardiac pathologies and is a fundamental pillar of cardiovascular medicine. Recent progress in deep learning has led to the development of robust automated…

Although approaches to Independent Component Analysis (ICA) based on characteristic function seem theoretically elegant, they may suffer from implementational challenges because of numerical integration steps or selection of tuning…

Methodology · Statistics 2025-11-07 Vincent Starck

Current pain assessment within hospitals often relies on self-reporting or non-specific EKG vital signs. This system leaves critically ill, sedated, and cognitively impaired patients vulnerable to undertreated pain and opioid overuse.…

Machine Learning · Computer Science 2025-10-08 Aavid Mathrawala , Dhruv Kurup , Josie Lau

In recent years, several methods have been proposed for the discovery of causal structure from non-experimental data (Spirtes et al. 2000; Pearl 2000). Such methods make various assumptions on the data generating process to facilitate its…

Machine Learning · Computer Science 2012-07-09 Shohei Shimizu , Aapo Hyvarinen , Yutaka Kano , Patrik O. Hoyer

Deciphering ion channel activity and signaling interactions within cells is one of the key tasks of neuroscience. Currently, measuring this electrophysiological activity is done using patch-clamp1-4 or voltage-sensitive imaging5-8.…

Biological Physics · Physics 2023-12-29 Qing-Yue Li , Pin-Tian Lyu , Bin Kang , Hong-Yuan Chen , Jing-Juan Xu

An alternative pathway for the human brain to communicate with the outside world is by means of a brain computer interface (BCI). A BCI can decode electroencephalogram (EEG) signals of brain activities, and then send a command or an intent…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Junhua Li , Zbigniew Struzik , Liqing Zhang , Andrzej Cichocki

Eye-movement related artifacts including blinks and saccades are significantly larger in amplitude than cortical activity as recorded by scalp electroencephalography (EEG), but are typically discarded in EEG studies focusing on cognitive…

Neurons and Cognition · Quantitative Biology 2025-08-20 Abhinav Uppal , Dillan Cellier , Min Suk Lee , Sean Bauersfeld , Yuchen Xu , Shihab A. Shamma , Gert Cauwenberghs , Virginia R. de Sa

Denoising wearable electroencephalogram (EEG) is inherently challenging since neural activity is not only subtle but also inseparable from spectrally overlapping noise artifacts. Classical signal processing methods, relying on fixed or…

Machine Learning · Computer Science 2026-05-11 Qiyu Rao , Haozhe Tian , Homayoun Hamedmoghadam , Danilo Mandic

Independent Component Analysis (ICA) offers interpretable semantic components of embeddings. While ICA theory assumes that embeddings can be linearly decomposed into independent components, real-world data often do not satisfy this…

Computation and Language · Computer Science 2024-10-10 Momose Oyama , Hiroaki Yamagiwa , Hidetoshi Shimodaira

Purpose: To evaluate a fully-automated deep-learning-based method for assessment of intracranial carotid artery calcification (ICAC). Methods: Two observers manually delineated ICAC in non-contrast CT scans of 2,319 participants (mean age…

Image and Video Processing · Electrical Eng. & Systems 2021-07-21 Gerda Bortsova , Daniel Bos , Florian Dubost , Meike W. Vernooij , M. Kamran Ikram , Gijs van Tulder , Marleen de Bruijne

Electroencephalography (EEG) plays a crucial role in brain-computer interfaces (BCIs) and neurological diagnostics, but its real-world deployment faces challenges due to noise artifacts, missing data, and high annotation costs. We introduce…

Signal Processing · Electrical Eng. & Systems 2025-10-24 Meghna Roy Chowdhury , Yi Ding , Shreyas Sen

Epilepsy is a neurological disorder arising from anomalies of the electrical activity in the brain, affecting about 0.5--0.8\% of the world population. Several studies investigated the relationship between seizures and brainwave…

Machine Learning · Computer Science 2018-01-25 Paolo Detti , Garazi Zabalo Manrique de Lara , Renato Bruni , Marco Pranzo , Francesco Sarnari

Independent component analysis (ICA) is popular in many applications, including cognitive neuroscience and signal processing. Due to computational constraints, principal component analysis is used for dimension reduction prior to ICA…

Methodology · Statistics 2017-10-03 Benjamin B. Risk , David S. Matteson , David Ruppert

Exploring brain activity in relation to visual perception provides insights into the biological representation of the world. While functional magnetic resonance imaging (fMRI) and magnetoencephalography (MEG) have enabled effective image…

Multimedia · Computer Science 2025-12-17 Shuqi Zhu , Ziyi Ye , Qingyao Ai , Yiqun Liu