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Arbor is a software library designed for efficient simulation of large-scale networks of biological neurons with detailed morphological structures. It combines customizable neuronal and synaptic mechanisms with high-performance computing,…

Computational Engineering, Finance, and Science · Computer Science 2026-02-16 Jannik Luboeinski , Sebastian Schmitt , Shirin Shafiee , Thorsten Hater , Fabian Bösch , Christian Tetzlaff

Computational neuroscience has traditionally focused on isolated scales, limiting understanding of brain function across multiple levels. While microscopic models capture biophysical details of neurons, macroscopic models describe…

Neurons and Cognition · Quantitative Biology 2025-12-17 Thorsten Hater , Juliette Courson , Han Lu , Sandra Diaz-Pier , Thanos Manos

Searching for geometric objects that are close in space is a fundamental component of many applications. The performance of search algorithms comes to the forefront as the size of a problem increases both in terms of total object count as…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-30 D. Lebrun-Grandié , A. Prokopenko , B. Turcksin , S. R. Slattery

As Graph Neural Networks (GNNs) become popular, libraries like PyTorch-Geometric (PyG) and Deep Graph Library (DGL) are proposed; these libraries have emerged as the de facto standard for implementing GNNs because they provide…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-02-29 Yi-Chien Lin , Yuyang Chen , Sameh Gobriel , Nilesh Jain , Gopi Krishna Jha , Viktor Prasanna

Over the past decade there has been a growing interest in the development of parallel hardware systems for simulating large-scale networks of spiking neurons. Compared to other highly-parallel systems, GPU-accelerated solutions have the…

Neurons and Cognition · Quantitative Biology 2021-02-22 Bruno Golosio , Gianmarco Tiddia , Chiara De Luca , Elena Pastorelli , Francesco Simula , Pier Stanislao Paolucci

The NEURON simulator has been developed over the past three decades and is widely used by neuroscientists to model the electrical activity of neuronal networks. Large network simulation projects using NEURON have supercomputer allocations…

Neurons and Cognition · Quantitative Biology 2019-01-31 Pramod Kumbhar , Michael Hines , Jeremy Fouriaux , Aleksandr Ovcharenko , James King , Fabien Delalondre , Felix Schürmann

A range of computational biology software (GROMACS, AMBER, NAMD, LAMMPS, OpenMM, Psi4 and RELION) was benchmarked on a representative selection of HPC hardware, including AMD EPYC 7742 CPU nodes, NVIDIA V100 and AMD MI250X GPU nodes, and an…

Objective: The advent of High-Performance Computing (HPC) in recent years has led to its increasing use in brain study through computational models. The scale and complexity of such models are constantly increasing, leading to challenging…

Neurosim is a fast, real-time, high-performance library for simulating sensors such as dynamic vision sensors, RGB cameras, depth sensors, and inertial sensors. It can also simulate agile dynamics of multi-rotor vehicles in complex and…

Robotics · Computer Science 2026-02-17 Richeek Das , Pratik Chaudhari

Open-source simulation tools play a crucial role for neuromorphic application engineers and hardware architects to investigate performance bottlenecks and explore design optimizations before committing to silicon. Reconfigurable…

Emerging Technologies · Computer Science 2024-04-26 Sahil Hassan , Michael Inouye , Miguel C. Gonzalez , Ilkin Aliyev , Joshua Mack , Maisha Hafiz , Ali Akoglu

Binary Neural Networks (BNNs) can drastically reduce memory size and accesses by applying bit-wise operations instead of standard arithmetic operations. Therefore it could significantly improve the efficiency and lower the energy…

Machine Learning · Computer Science 2017-05-31 Haojin Yang , Martin Fritzsche , Christian Bartz , Christoph Meinel

This paper assesses and reports the experience of ten teams working to port,validate, and benchmark several High Performance Computing applications on a novel GPU-accelerated Arm testbed system. The testbed consists of eight NVIDIA Arm HPC…

Large language models struggle to maintain strict adherence to structured workflows in high-stakes domains such as healthcare triage. Monolithic approaches that encode entire decision structures within a single prompt are prone to…

Artificial Intelligence · Computer Science 2026-03-03 Luís Silva , Diogo Gonçalves , Catarina Farinha , Clara Matos , Luís Ungaro

Training modern deep learning models requires large amounts of computation, often provided by GPUs. Scaling computation from one GPU to many can enable much faster training and research progress but entails two complications. First, the…

Machine Learning · Computer Science 2018-02-22 Alexander Sergeev , Mike Del Balso

With the announcement that the Aurora Supercomputer will be composed of general purpose Intel CPUs complemented by discrete high performance Intel GPUs, and the deployment of the oneAPI ecosystem, Intel has committed to enter the arena of…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-19 Yuhsiang M. Tsai , Terry Cojean , Hartwig Anzt

GPUs are now used for a wide range of problems within HPC. However, making efficient use of the computational power available with multiple GPUs is challenging. The main challenges in achieving good performance are memory layout, affecting…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-20 Robert Clucas , Philip Blakely , Nikolaos Nikiforakis

Neuroscience models commonly have a high number of degrees of freedom and only specific regions within the parameter space are able to produce dynamics of interest. This makes the development of tools and strategies to efficiently find…

We investigate the energy efficiency of a library designed for parallel computations with sparse matrices. The library leverages high-performance, energy-efficient Graphics Processing Unit (GPU) accelerators to enable large-scale scientific…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-16 Massimo Bernaschi , Alessandro Celestini , Pasqua D'Ambra , Giorgio Richelli

Both in electronics and biology, physical implementations of neural networks have severe energy and memory constraints. We propose a hardware-software co-design approach for minimizing the use of memory resources in multi-core neuromorphic…

Neural and Evolutionary Computing · Computer Science 2022-03-02 Vanessa R. C. Leite , Zhe Su , Adrian M. Whatley , Giacomo Indiveri

Future computing systems, from handhelds to supercomputers, will undoubtedly be more parallel and heterogeneous than todays systems to provide more performance and energy efficiency. Thus, GPUs are increasingly being used to accelerate…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-18 Saeed Taheri , Apan Qasem , Martin Burtscher
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