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Cell nuclei detection and fine-grained classification have been fundamental yet challenging problems in histopathology image analysis. Due to the nuclei tiny size, significant inter-/intra-class variances, as well as the inferior image…

Computer Vision and Pattern Recognition · Computer Science 2017-12-25 Yanning Zhou , Qi Dou , Hao Chen , Jing Qin , Pheng-Ann Heng

Contrasting the previous evidence that neurons in the later layers of a Convolutional Neural Network (CNN) respond to complex object shapes, recent studies have shown that CNNs actually exhibit a `texture bias': given an image with both…

Computer Vision and Pattern Recognition · Computer Science 2021-01-28 Md Amirul Islam , Matthew Kowal , Patrick Esser , Sen Jia , Bjorn Ommer , Konstantinos G. Derpanis , Neil Bruce

Today, deep convolutional neural networks (CNNs) have demonstrated state of the art performance for supervised medical image segmentation, across various imaging modalities and tasks. Despite early success, segmentation networks may still…

Computer Vision and Pattern Recognition · Computer Science 2020-11-24 Rosana El Jurdi , Caroline Petitjean , Paul Honeine , Veronika Cheplygina , Fahed Abdallah

This paper proposes a novel regularization approach to bias Convolutional Neural Networks (CNNs) toward utilizing edge and line features in their hidden layers. Rather than learning arbitrary kernels, we constrain the convolution layers to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Christoph Linse , Beatrice Brückner , Thomas Martinetz

Quantitative Susceptibility Mapping (QSM) estimates tissue magnetic susceptibility distributions from Magnetic Resonance (MR) phase measurements by solving an ill-posed dipole inversion problem. Conventional single orientation QSM methods…

Image and Video Processing · Electrical Eng. & Systems 2020-08-13 Kuo-Wei Lai , Manisha Aggarwal , Peter van Zijl , Xu Li , Jeremias Sulam

Automated surface segmentation is important and challenging in many medical image analysis applications. Recent deep learning based methods have been developed for various object segmentation tasks. Most of them are a classification based…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Leixin Zhou , Xiaodong Wu

Automatic cell detection in histology images is a challenging task due to varying size, shape and features of cells and stain variations across a large cohort. Conventional deep learning methods regress the probability of each pixel…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Shan E Ahmed Raza , Khalid AbdulJabbar , Mariam Jamal-Hanjani , Selvaraju Veeriah , John Le Quesne , Charles Swanton , Yinyin Yuan

Convolutional neural networks (CNNs) show outstanding performance in many image processing problems, such as image recognition, object detection and image segmentation. Semantic segmentation is a very challenging task that requires…

Computer Vision and Pattern Recognition · Computer Science 2019-07-12 Fan Jia , Jun Liu , Xue-cheng Tai

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Deep learning has gained great success in various classification tasks. Typically, deep learning models learn underlying features directly from data, and no underlying relationship between classes are included. Similarity between classes…

Computer Vision and Pattern Recognition · Computer Science 2020-09-28 Xueli Xiao , Chunyan Ji , Thosini Bamunu Mudiyanselage , Yi Pan

Past few years have witnessed exponential growth of interest in deep learning methodologies with rapidly improving accuracies and reduced computational complexity. In particular, architectures using Convolutional Neural Networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Sai Samarth R Phaye , Apoorva Sikka , Abhinav Dhall , Deepti Bathula

Convolutional Neural Networks (CNNs) have recently led to incredible breakthroughs on a variety of pattern recognition problems. Banks of finite impulse response filters are learned on a hierarchy of layers, each contributing more abstract…

Computer Vision and Pattern Recognition · Computer Science 2017-07-18 Felipe Petroski Such , Shagan Sah , Miguel Dominguez , Suhas Pillai , Chao Zhang , Andrew Michael , Nathan Cahill , Raymond Ptucha

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

An important goal in visual recognition is to devise image representations that are invariant to particular transformations. In this paper, we address this goal with a new type of convolutional neural network (CNN) whose invariance is…

Computer Vision and Pattern Recognition · Computer Science 2015-01-08 Julien Mairal , Piotr Koniusz , Zaid Harchaoui , Cordelia Schmid

State-of-the-art radio observatories produce large amounts of data which can be used to study the properties of radio galaxies. However, with this rapid increase in data volume, it has become unrealistic to manually process all of the…

Instrumentation and Methods for Astrophysics · Physics 2023-04-12 Kevin Brand , Trienko L. Grobler , Waldo Kleynhans , Mattia Vaccari , Matthew Prescott , Burger Becker

Semantic segmentation is an important preliminary step towards automatic medical image interpretation. Recently deep convolutional neural networks have become the first choice for the task of pixel-wise class prediction. While incorporating…

Computer Vision and Pattern Recognition · Computer Science 2018-06-25 Zahra Mirikharaji , Ghassan Hamarneh

Scene parsing is an important and challenging prob- lem in computer vision. It requires labeling each pixel in an image with the category it belongs to. Tradition- ally, it has been approached with hand-engineered features from color…

Machine Learning · Statistics 2014-11-18 Rahul Mohan

Automatic detection and segmentation of cells and nuclei in microscopy images is important for many biological applications. Recent successful learning-based approaches include per-pixel cell segmentation with subsequent pixel grouping, or…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Uwe Schmidt , Martin Weigert , Coleman Broaddus , Gene Myers

Convolutional Neural Network (CNN) image classifiers are traditionally designed to have sequential convolutional layers with a single output layer. This is based on the assumption that all target classes should be treated equally and…

Computer Vision and Pattern Recognition · Computer Science 2017-10-06 Xinqi Zhu , Michael Bain

Modern deep neural networks require a tremendous amount of data to train, often needing hundreds or thousands of labeled examples to learn an effective representation. For these networks to work with less data, more structure must be built…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Reuben Feinman , Brenden M. Lake