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Coherent Anti-Stokes Raman Scattering (CARS) processes are ``coherent,'' but the phase of the anti-Stokes radiation is usually lost by most incoherent spectroscopic CARS measurements. We propose a novel Raman microscopy imaging method…

Optics · Physics 2009-11-10 D. L. Marks , S. A. Boppart

We propose a new technique for comparing two Raman active samples. The method employs optical interference of the signals generated via coherent anti-Stokes Raman scattering (CARS) of broadband laser pulses with noisy spectra. It does not…

Quantum Physics · Physics 2015-05-27 Evgeny A. Shapiro , Stanislav O. Konorov , Valery Milner

Raman spectroscopy is one of the key techniques in the study of vibrational modes and molecular structures. In Coherent Anti-Stokes Raman Scattering (CARS) spectroscopy, a molecular vibrational spectrum is resolved via the third-order…

Optics · Physics 2010-12-02 Ori Katz , Jonathan M. Levitt , Eran Grinvald , Yaron Silberberg

We have developed an interferometric implementation of coherent anti-Stokes Raman scattering (CARS) which enables broadband coherent Raman spectroscopy free from non-resonant background (NRB), with a signal strength proportional to…

Optics · Physics 2014-02-25 Brad Littleton , Thomas Kavanagh , Frederic Festy , David Richards

Coherent Anti Stokes Raman Scattering (CARS) offers many advantages for nonlinear bio-imaging, thanks to its sub-cellular spatial resolution and unique chemical specificity. Its working principle requires two incident pulsed laser beams…

Coherent Raman scattering (CRS) spectroscopy techniques have been widely developed and optimized for different applications in biomedicine and fundamental science. The most utilized CRS technique has been coherent anti-Stokes Raman…

Optics · Physics 2020-03-05 Pavel Kolesnichenko , Jonathan O. Tollerud , Jeffrey A. Davis

Since its first demonstration in the sixties, coherent anti-Stokes Raman scattering (CARS) has become a powerful spectroscopic sensing tool with broad applications in biology and chemistry. However, it is a complex nonlinear optical process…

Optics · Physics 2020-07-15 Gombojav O. Ariunbold , Supriya Nagpal , Bryan Semon

The ability to enhance resonant signals and eliminate the non-resonant background is analyzed for Coherent Anti-Stokes Raman Scattering (CARS). The analysis is done at a specific frequency as well as for broadband excitation using…

Quantum Physics · Physics 2015-03-19 Fang Gao , Feng Shuang , JunHui Shi , Herschel Rabitz , HaiFeng Wang , JiXin Cheng

Single-shot time resolved Coherent Anti-Stokes Raman Scattering (CARS) is presented as a viable method for fast measurements of molecular spectra. The method is based on the short spatial extension of femtosecond pulses and maps time delays…

Optics · Physics 2009-11-13 Yuri Paskover , I. Sh. Averbukh , Yehiam Prior

A new interferometric technique is demonstrated for measuring Coherent Anti-Stokes Raman Scattering (CARS) signals. Two forward-directed CARS signals are generated, one in each arm of an interferometer. The deterministic nature of the CARS…

Optics · Physics 2007-05-23 J. S. Bredfeldt , D. L. Marks , C. Vinegoni , S. Hambir , S. A. Boppart

Coherent anti-Stokes Raman scattering (CARS) microspectroscopy has demonstrated significant potential for biological and materials imaging. To date, however, the primary mechanism of disseminating CARS spectroscopic information is through…

Optics · Physics 2015-10-08 Charles H. Camp , Young Jong Lee , Marcus T. Cicerone

We demonstrate a single-beam, standoff (>10m) coherent anti-Stokes Raman scattering spectroscopy (CARS) of various materials, including trace amounts of explosives and nitrate samples, under ambient light conditions. The multiplex…

Optics · Physics 2010-12-02 O. Katz , A. Natan , S. Rosenwaks , Y. Silberberg

The motion of atoms is at the heart of any chemical or structural transformation in molecules and materials. Upon activation of this motion by an external source, several (usually many) vibrational modes can be coherently coupled, thus…

Broadband coherent anti-Stokes Raman scattering (CARS) spectroscopy plays a vital role in chemical sensing and label-free vibrational imaging, yet conventional methods suffer from limited acquisition speeds and complex detection schemes.…

Optics · Physics 2025-07-23 Jing Hu , Tianjian Lv , Zhaoyang Wen , Wending Huang , Ming Yan , Heping Zeng

Raman scattering signal can be enhanced through localization of incident field into sub-wavelength hot-spots through plasmonic nano-structures (Surface-enhanced Raman scattering-SERS). Recently, further enhancement of SERS signal via…

We present a double-resonant Raman mode in few-layer graphene, which is able to probe the number of graphene layers reliably. This so-called N mode on the low-frequency side of the G mode results from a double-resonant Stokes/anti-Stokes…

Materials Science · Physics 2012-06-28 Felix Herziger , Patrick May , Janina Maultzsch

We propose an all-fiber-generated dual-soliton pulses based scheme for the background-free detection of coherent anti-Stokes Raman spectroscopy under the spectral focusing mechanism. Due to the strong birefringence and high nonlinearity of…

Optics · Physics 2016-05-30 Kun Chen , Tao Wu , Haoyun Wei , Yan Li

: Non-resonant background (NRB) plays a significant role in coherent anti-Stokes Raman scattering (CARS) spectroscopic applications. All the recent works primarily focused on removing the NRB using different deep learning methods, and only…

We propose a novel approach using Multiplex-Coherent Anti-Stokes Raman Scattering (M-CARS) for la-bel-free discriminations in biomedical tissues. The strategy is based on the evaluation of the contrast be-tween resonant and nonresonant…

We have developed a coherent Raman imaging platform using broadband coherent anti-Stokes Raman scattering (BCARS) that provides an unprecedented combination of speed, sensitivity, and spectral breadth. The system utilizes a unique…

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