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This work introduces MICSim, an open-source, pre-circuit simulator designed for early-stage evaluation of chip-level software performance and hardware overhead of mixed-signal compute-in-memory (CIM) accelerators. MICSim features a modular…

Artificial Intelligence · Computer Science 2024-12-18 Cong Wang , Zeming Chen , Shanshi Huang

Developing an efficient method to accelerate the speed of molecular dynamics is a central theme in the field of molecular simulation. One category among the methods are collective-variable-based methods, which rely on predefined collective…

Chemical Physics · Physics 2024-08-27 Jiahao Fan , Yanze Wang , Dongdong Wang , Linfeng Zhang

The rapidly growing popularity and scale of data-parallel workloads demand a corresponding increase in raw computational power of GPUs (Graphics Processing Units). As single-GPU systems struggle to satisfy the performance demands, multi-GPU…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-15 Yifan Sun , Trinayan Baruah , Saiful A. Mojumder , Shi Dong , Rafael Ubal , Xiang Gong , Shane Treadway , Yuhui Bao , Vincent Zhao , José L. Abellán , John Kim , Ajay Joshi , David Kaeli

We propose residual denoising diffusion models (RDDM), a novel dual diffusion process that decouples the traditional single denoising diffusion process into residual diffusion and noise diffusion. This dual diffusion framework expands the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Jiawei Liu , Qiang Wang , Huijie Fan , Yinong Wang , Yandong Tang , Liangqiong Qu

We present GridFF, an efficient method for simulating molecules on rigid substrates, derived from techniques used in protein-ligand docking in biochemistry. By projecting molecule-substrate interactions onto precomputed spatial grids with…

Chemical Physics · Physics 2025-08-22 Indranil Mal , Milan Kočí , Paolo Nicolini , Prokop Hapala

We present a demonstration of REACT, a new Real-time Educational AI-powered Classroom Tool that employs EDM techniques for supporting the decision-making process of educators. REACT is a data-driven tool with a user-friendly graphical…

Computers and Society · Computer Science 2021-08-18 Ajay Kulkarni , Olga Gkountouna

High-speed chemically active flows present significant computational challenges due to their disparate space and time scales, where stiff chemistry often dominates simulation time. While modern supercomputing scientific codes achieve…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-04 Anthony Carreon , Jagmohan Singh , Shivank Sharma , Shuzhi Zhang , Venkat Raman

Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…

Detector simulation and reconstruction are a significant computational bottleneck in particle physics. We develop Particle-flow Neural Assisted Simulations (Parnassus) to address this challenge. Our deep learning model takes as input a…

Data Analysis, Statistics and Probability · Physics 2024-11-22 Etienne Dreyer , Eilam Gross , Dmitrii Kobylianskii , Vinicius Mikuni , Benjamin Nachman , Nathalie Soybelman

This paper is centered on using chemical reaction as a computational metaphor for simultaneously solving problems. An artificial chemical reactor that can simultaneously solve instances of three unrelated problems was created. The reactor…

Emerging Technologies · Computer Science 2015-06-30 Jaderick P. Pabico

Liquid argon time projection chambers (LArTPCs) are widely used in particle detection for their tracking and calorimetric capabilities. The particle physics community actively builds and improves high-quality simulators for such detectors…

Instrumentation and Detectors · Physics 2023-09-12 Sean Gasiorowski , Yifan Chen , Youssef Nashed , Pierre Granger , Camelia Mironov , Daniel Ratner , Kazuhiro Terao , Ka Vang Tsang

The molecular energies of chemical systems have been successfully calculated on quantum computers, however, more attention has been paid to the dynamic process of chemical reactions in practical application, especially in catalyst design,…

Quantum Physics · Physics 2023-03-28 Qiankun Gong , Qingmin Man , Ye Li , Menghan Dou , Qingchun Wang , Yu-Chun Wu , Guo-Ping Guo

In reactive controller synthesis, a number of implementations (controllers) are possible for a given specification because of the incomplete nature of specification. To choose the most desirable one from the various options, we need to…

Logic in Computer Science · Computer Science 2019-05-28 Amol Wakankar , Paritosh K. Pandya , Rajmohan Matteplackel

Dose-finding trials are a key component of the drug development process and rely on a statistical design to help inform dosing decisions. Triallists wishing to choose a design require knowledge of operating characteristics of competing…

Computation · Statistics 2025-03-11 Michael Sweeting , Daniel Slade , Dan Jackson , Kristian Brock

We introduce a particle-based simulation method for granular material in interactive frame rates. We divide the simulation into two decoupled steps. In the first step, a relatively small number of particles is accurately simulated with a…

Graphics · Computer Science 2023-08-04 Alexander Sommer , Ulrich Schwanecke , Elmar Schömer

In this extended abstract, we have introduced a highly memory-efficient state vector simulation of quantum circuits premised on data compression, harnessing the capabilities of both CPUs and GPUs. We have elucidated the inherent challenges…

Quantum Physics · Physics 2023-10-02 Boyuan Zhang , Bo Fang , Qiang Guan , Ang Li , Dingwen Tao

Efficient hybrid DFT simulations of solid state materials would be extremely beneficial for computational chemistry and materials science, but is presently bottlenecked by difficulties in computing Hartree-Fock (HF) exchange with plane wave…

Chemical Physics · Physics 2024-10-30 Yuanheng Wang , Diptarka Hait , Pablo A. Unzueta , Juncheng Harry Zhang , Todd J. Martínez

Learning pair interactions from experimental or simulation data is of great interest for molecular simulations. We propose a general stochastic method for learning pair interactions from data using differentiable simulations (DiffSim).…

Chemical Physics · Physics 2023-02-08 Wujie Wang , Zhenghao Wu , Rafael Gómez-Bombarelli

Diffusion-based Molecular Communication (MC) is inherently challenged by severe inter-symbol interference (ISI). This is significantly amplified in mobile scenarios, where the channel impulse response (CIR) becomes time-varying and…

Emerging Technologies · Computer Science 2025-11-13 Abdulkadir Bilge , Eren Akyol , Murat Kuscu

Turbulent flows and fluid-structure interactions (FSI) are ubiquitous in scientific and engineering applications, but their accurate and efficient simulation remains a major challenge due to strong nonlinearities, multiscale interactions,…

Fluid Dynamics · Physics 2025-06-02 Xiantao Fan , Xinyang Liu , Meng Wang , Jian-Xun Wang