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This paper studies MapReduce-based heterogeneous coded distributed computing (CDC) where, besides different computing capabilities at workers, input files to be accessed by computing jobs have nonuniform popularity. We propose a file…

Information Theory · Computer Science 2024-10-22 Yong Deng , Min Dong

The majority of contemporary mobile devices and personal computers are based on heterogeneous computing platforms that consist of a number of CPU cores and one or more Graphics Processing Units (GPUs). Despite the high volume of these…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-02-20 Jani Boutellier , Jiahao Wu , Heikki Huttunen , Shuvra S. Bhattacharyya

Heterogeneous multi-core architectures combine a few "host" cores, optimized for single-thread performance, with many small energy-efficient "accelerator" cores for data-parallel processing, on a single chip. Offloading a computation to the…

Hardware Architecture · Computer Science 2025-11-11 Luca Colagrande , Luca Benini

Heterogeneous systems are becoming more common on High Performance Computing (HPC) systems. Even using tools like CUDA and OpenCL it is a non-trivial task to obtain optimal performance on the GPU. Approaches to simplifying this task include…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-01-11 Marek Blazewicz , Steven R. Brandt , Peter Diener , David M. Koppelman , Krzysztof Kurowski , Frank Löffler , Erik Schnetter , Jian Tao

Monte Carlo / Dynamic Code (MC/DC) is a portable Monte Carlo neutron transport package for rapid numerical methods exploration in heterogeneous and HPC contexts, developed under the auspices of the Center for Exascale Monte Carlo Neutron…

Computational Physics · Physics 2025-06-03 Braxton Cuneo , Joanna Piper Morgan , Ilham Variansyah , Kyle E. Niemeyer

Understanding how proteins structurally interact is crucial to modern biology, with applications in drug discovery and protein design. Recent machine learning methods have formulated protein-small molecule docking as a generative problem…

Despite the great popularity of virtual screening of existing compound libraries, the search for new potential drug candidates also takes advantage of generative protocols, where new compound suggestions are enumerated using various…

Biomolecules · Quantitative Biology 2023-12-22 Tomasz Danel , Jan Łęski , Sabina Podlewska , Igor T. Podolak

Docking is an important tool in computational drug discovery that aims to predict the binding pose of a ligand to a target protein through a combination of pose scoring and optimization. A scoring function that is differentiable with…

Machine Learning · Statistics 2017-10-23 Matthew Ragoza , Lillian Turner , David Ryan Koes

We present a portable platform, called PIC_ENGINE, for accelerating Particle-In-Cell (PIC) codes on heterogeneous many-core architectures such as Graphic Processing Units (GPUs). The aim of this development is efficient simulations on…

Computational Physics · Physics 2016-06-08 F. Hariri , T. M. Tran , A. Jocksch , E. Lanti , J. Progsch , P. Messmer , S. Brunner , G. Gheller , L. Villard

Modern drug discovery is often time-consuming, complex and cost-ineffective due to the large volume of molecular data and complicated molecular properties. Recently, machine learning algorithms have shown promising results in virtual…

Neural and Evolutionary Computing · Computer Science 2022-02-08 Dongning Ma , Rahul Thapa , Xun Jiao

Currently, the most energy-efficient hardware platforms for floating point-intensive calculations (also known as High Performance Computing, or HPC) are graphical processing units (GPUs). However, porting existing scientific codes to GPUs…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-28 Michele Martone , Julia Lawall

Properties of molecules are indicative of their functions and thus are useful in many applications. With the advances of deep learning methods, computational approaches for predicting molecular properties are gaining increasing momentum.…

Quantitative Methods · Quantitative Biology 2021-07-07 Zhengyang Wang , Meng Liu , Youzhi Luo , Zhao Xu , Yaochen Xie , Limei Wang , Lei Cai , Qi Qi , Zhuoning Yuan , Tianbao Yang , Shuiwang Ji

Cutting edge classical computing today relies on a combination of CPU-based computing with a strong reliance on accelerators. In particular, high-performance computing (HPC) and machine learning (ML) rely heavily on acceleration via GPUs…

Quantum Physics · Physics 2026-03-11 Atulya Mahesh , Swastik Mittal , Frank Mueller

Hardware accelerators, such as those based on GPUs and FPGAs, offer an excellent opportunity to efficiently parallelize functionalities. Recently, modern embedded platforms started being equipped with such accelerators, resulting in a…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-16 Daniel Casini , Paolo Pazzaglia , Alessandro Biondi , Marco Di Natale

The Massive Parallel Computation (MPC) model is a theoretical framework for popular parallel and distributed platforms such as MapReduce, Hadoop, or Spark. We consider the task of computing a large matching or small vertex cover in this…

Data Structures and Algorithms · Computer Science 2018-07-24 Krzysztof Onak

We discuss the computational bottlenecks in molecular dynamics (MD) and describe the challenges in parallelizing the computation intensive tasks. We present a hybrid algorithm using MPI (Message Passing Interface) with OpenMP threads for…

Computational Physics · Physics 2015-07-28 Anirban Pal , Abhishek Agarwala , Soumyendu Raha , Baidurya Bhattacharya

Heterogeneous computing systems, which combine general-purpose processors with specialized accelerators, are increasingly important for optimizing the performance of modern applications. A central challenge is to decide which parts of an…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-15 Martin Wilhelm , Franz Freitag , Max Tzschoppe , Thilo Pionteck

The parallel and distributed processing are becoming de facto industry standard, and a large part of the current research is targeted on how to make computing scalable and distributed, dynamically, without allocating the resources on…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-10 Rajendra Purohit , K R Chowdhary , S D Purohit

Several high-throughput distributed data-processing applications require multi-hop processing of streams of data. These applications include continual processing on data streams originating from a network of sensors, composing a multimedia…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-03-26 Shah Asaduzzaman , Muthucumaru Maheswaran

Many high end and next generation computing systems to incorporated alternative memory technologies to meet performance goals. Since these technologies present distinct advantages and tradeoffs compared to conventional DDR* SDRAM, such as…

Performance · Computer Science 2021-10-06 M. Ben Olson , Brandon Kammerdiener , Kshitij A. Doshi , Terry Jones , Michael R. Jantz