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Deep learning-based medical image segmentation models, such as U-Net, rely on high-quality annotated datasets to achieve accurate predictions. However, the increasing use of generative models for synthetic data augmentation introduces…

Image and Video Processing · Electrical Eng. & Systems 2025-02-07 Tianhao Li , Tianyu Zeng , Yujia Zheng , Chulong Zhang , Jingyu Lu , Haotian Huang , Chuangxin Chu , Fang-Fang Yin , Zhenyu Yang

Magnetic resonance images (MRI) play an important role in supporting and substituting clinical information in the diagnosis of multiple sclerosis (MS) disease by presenting lesion in brain MR images. In this paper, an algorithm for MS…

Image and Video Processing · Electrical Eng. & Systems 2018-04-11 Saba Heidari Gheshlaghi , Abolfazl Madani , AmirAbolfazl Suratgar , Fardin Faraji

In this paper we propose a novel method for the segmentation of longitudinal brain MRI scans of patients suffering from Multiple Sclerosis. The method builds upon an existing cross-sectional method for simultaneous whole-brain and lesion…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Stefano Cerri , Andrew Hoopes , Douglas N. Greve , Mark Mühlau , Koen Van Leemput

Data augmentation can effectively resolve a scarcity of images when training machine-learning algorithms. It can make them more robust to unseen images. We present a lesion conditional Generative Adversarial Network LcGAN to generate…

Image and Video Processing · Electrical Eng. & Systems 2020-08-10 Manohar Karki , Junghwan Cho , Seokhwan Ko

Fully convolutional deep neural networks have been asserted to be fast and precise frameworks with great potential in image segmentation. One of the major challenges in training such networks raises when data is unbalanced, which is common…

Computer Vision and Pattern Recognition · Computer Science 2018-12-17 Seyed Raein Hashemi , Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Sanjay P. Prabhu , Simon K. Warfield , Ali Gholipour

In this paper, we address the problem of synthesizing multi-parameter magnetic resonance imaging (mp-MRI) data, i.e. Apparent Diffusion Coefficients (ADC) and T2-weighted (T2w), containing clinically significant (CS) prostate cancer (PCa)…

Machine Learning · Computer Science 2018-12-18 Zhiwei Wang , Yi Lin , Kwang-Ting Cheng , Xin Yang

Training of semantic segmentation models for material analysis requires micrographs and their corresponding masks. It is quite unlikely that perfect masks will be drawn, especially at the edges of objects, and sometimes the amount of data…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Matias Oscar Volman Stern , Dominic Hohs , Andreas Jansche , Timo Bernthaler , Gerhard Schneider

As a pragmatic data augmentation tool, data synthesis has generally returned dividends in performance for deep learning based medical image analysis. However, generating corresponding segmentation masks for synthetic medical images is…

Image and Video Processing · Electrical Eng. & Systems 2023-03-23 Xiaodan Xing , Giorgos Papanastasiou , Simon Walsh , Guang Yang

Background: Accurate lesion segmentation is critical for multiple sclerosis (MS) diagnosis, yet current deep learning approaches face robustness challenges. Aim: This study improves MS lesion segmentation by combining data fusion and deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-18 Nadezhda Alsahanova , Pavel Bartenev , Maksim Sharaev , Milos Ljubisavljevic , Taleb Al. Mansoori , Yauhen Statsenko

Precision medicine for chronic diseases such as multiple sclerosis (MS) involves choosing a treatment which best balances efficacy and side effects/preferences for individual patients. Making this choice as early as possible is important,…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Joshua Durso-Finley , Jean-Pierre R. Falet , Brennan Nichyporuk , Douglas L. Arnold , Tal Arbel

We present a method to segment MRI scans of the human brain into ischemic stroke lesion and normal tissues. We propose a neural network architecture in the form of a standard encoder-decoder where predictions are guided by a spatial…

Image and Video Processing · Electrical Eng. & Systems 2021-09-21 Alex Wong , Allison Chen , Yangchao Wu , Safa Cicek , Alexandre Tiard , Byung-Woo Hong , Stefano Soatto

Medical image analysis using deep neural networks has been actively studied. Deep neural networks are trained by learning data. For accurate training of deep neural networks, the learning data should be sufficient, of good quality, and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Sunho Kim , Byungjai Kim , HyunWook Park

Insufficiency of training data is a persistent issue in medical image analysis, especially for task-based functional magnetic resonance images (fMRI) with spatio-temporal imaging data acquired using specific cognitive tasks. In this paper,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Jiyao Wang , Nicha C. Dvornek , Lawrence H. Staib , James S. Duncan

This work is motivated by a study of a population of multiple sclerosis (MS) patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify active brain lesions. At each visit, a contrast agent is administered…

Applications · Statistics 2013-06-25 Haochang Shou , Russell T. Shinohara , Han Liu , Daniel S. Reich , Ciprian M. Crainiceanu

Accurate medical image segmentation is critical for early medical diagnosis. Most existing methods are based on U-shape structure and use element-wise addition or concatenation to fuse different level features progressively in decoder.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Xiaoqi Zhao , Hongpeng Jia , Youwei Pang , Long Lv , Feng Tian , Lihe Zhang , Weibing Sun , Huchuan Lu

Synthesizing missing modalities in multi-modal magnetic resonance imaging (MRI) is vital for ensuring diagnostic completeness, particularly when full acquisitions are infeasible due to time constraints, motion artifacts, and patient…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yue Zhang , Zhizheng Zhuo , Siyao Xu , Shan Lv , Zhaoxi Liu , Jun Qiu , Qiuli Wang , Yaou Liu , S. Kevin Zhou

Multiple sclerosis (MS) lesions occupy a small fraction of the brain volume, and are heterogeneous with regards to shape, size and locations, which poses a great challenge for training deep learning based segmentation models. We proposed a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Hang Zhang , Jinwei Zhang , Rongguang Wang , Qihao Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Yi Wang

Acute stroke lesion segmentation tasks are of great clinical interest as they can help doctors make better informed treatment decisions. Magnetic resonance imaging (MRI) is time demanding but can provide images that are considered gold…

Computer Vision and Pattern Recognition · Computer Science 2019-04-25 Albert Clèrigues , Sergi Valverde , Jose Bernal , Jordi Freixenet , Arnau Oliver , Xavier Lladó

Multiple Sclerosis (MS) is a chronic neurological condition characterized by the development of lesions in the white matter of the brain. T2-fluid attenuated inversion recovery (FLAIR) brain magnetic resonance imaging (MRI) provides…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Jueqi Wang , Derek Berger , Erin Mazerolle , Jean-Alexis Delamer , Jacob Levman

Recently, segmentation methods based on Convolutional Neural Networks (CNNs) showed promising performance in automatic Multiple Sclerosis (MS) lesions segmentation. These techniques have even outperformed human experts in controlled…

Image and Video Processing · Electrical Eng. & Systems 2021-07-26 Reda Abdellah Kamraoui , Vinh-Thong Ta , Thomas Tourdias , Boris Mansencal , José V Manjon , Pierrick Coupé