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Mechanistic understanding and rational design of complex chemical systems depend on fast and accurate predictions of electronic structures beyond individual building blocks. However, if the system exceeds hundreds of atoms, first-principles…

Chemical Physics · Physics 2026-04-13 Siqi Chen , Zhiqiang Wang , Yili Shen , Xianqi Deng , Xi Cheng , Cheng-Wei Ju , Jun Yi , Guo Ling , Dieaa Alhmoud , Hui Guan , Zhou Lin

In molecular dynamics (MD), neural network (NN) potentials trained bottom-up on quantum mechanical data have seen tremendous success recently. Top-down approaches that learn NN potentials directly from experimental data have received less…

Chemical Physics · Physics 2021-11-29 Stephan Thaler , Julija Zavadlav

To further develop accurate and large-scale simulations of electrochemical interfaces, we propose a unified explicit electric potential framework to simultaneously predict atomic forces and electron density distributions. The framework…

Chemical Physics · Physics 2026-04-14 Jingwen Zhou , Yawen Yu , Xuwei Liu , Chungen Liu

High-accuracy, high-efficiency physics-based fluid-solid interaction is essential for reality modeling and computer animation in online games or real-time Virtual Reality (VR) systems. However, the large-scale simulation of incompressible…

Graphics · Computer Science 2023-05-08 Jin Li , Yang Gao , Ju Dai , Shuai Li , Aimin Hao , Hong Qin

In this work, we explore the use of deep learning techniques to learn how nuclear cross sections change as we add or remove protons and neutrons. As a proof of principle, we focus on the neutron-induced reactions in the fast energy regime.…

We created a computational workflow to analyze the potential energy surface (PES) of materials using machine-learned interatomic potentials in conjunction with the minima hopping algorithm. We demonstrate this method by producing a…

Materials Science · Physics 2025-02-14 Hossein Tahmasbi , Kushal Ramakrishna , Mani Lokamani , Attila Cangi

While molecular dynamics (MD) is a very useful computational method for atomistic simulations, modeling the interatomic interactions for reliable MD simulations of real materials has been a long-standing challenge. In 2007, Behler and…

Materials Science · Physics 2025-06-11 Ling Tang , Weiyi Xia , Gayatri Viswanathan , Ernesto Soto , Kirill Kovnir , Cai-Zhuang Wang

Geometric deep learning has been revolutionizing the molecular modeling field. Despite the state-of-the-art neural network models are approaching ab initio accuracy for molecular property prediction, their applications, such as drug…

Chemical Physics · Physics 2023-08-17 Yusong Wang , Shaoning Li , Xinheng He , Mingyu Li , Zun Wang , Nanning Zheng , Bin Shao , Tie-Yan Liu , Tong Wang

Machine learning assisted modeling of the inter-atomic potential energy surface (PES) is revolutionizing the field of molecular simulation. With the accumulation of high-quality electronic structure data, a model that can be pretrained on…

Chemical Physics · Physics 2023-09-18 Duo Zhang , Hangrui Bi , Fu-Zhi Dai , Wanrun Jiang , Linfeng Zhang , Han Wang

Conventional molecular dynamics (MD) simulation approaches, such as $\textit{ab initio}$ MD (AIMD) and empirical force field MD (EFFMD), face significant trade-offs between physical accuracy and computational efficiency. This work presents…

Disordered Systems and Neural Networks · Physics 2026-05-12 Hongyu Yan , Yong Wei , Minghan Chen , Hanning Chen

Neural network (NN) models are increasingly used in scientific simulations, AI, and other high performance computing (HPC) fields to extract knowledge from datasets. Each dataset requires tailored NN model architecture, but designing…

Machine Learning · Computer Science 2021-08-12 Ariel Keller Rorabaugh , Silvina Caíno-Lores , Michael R. Wyatt , Travis Johnston , Michela Taufer

Representing a signal as a continuous function parameterized by neural network (a.k.a. Implicit Neural Representations, INRs) has attracted increasing attention in recent years. Neural Processes (NPs), which model the distributions over…

Machine Learning · Computer Science 2023-02-22 Zongyu Guo , Cuiling Lan , Zhizheng Zhang , Yan Lu , Zhibo Chen

Physics-aware deep learning (PADL) has gained popularity for use in complex spatiotemporal dynamics (field evolution) simulations, such as those that arise frequently in computational modeling of energetic materials (EM). Here, we show that…

Materials Science · Physics 2025-12-16 Zoë J. Gray , Joseph B. Choi , Youngsoo Choi , H. Keo Springer , H. S. Udaykumar , Stephen S. Baek

Physics-informed neural networks (PINNs) have recently become a powerful tool for solving partial differential equations (PDEs). However, finding a set of neural network parameters that lead to fulfilling a PDE can be challenging and…

Machine Learning · Computer Science 2023-04-12 Aleksandr Dekhovich , Marcel H. F. Sluiter , David M. J. Tax , Miguel A. Bessa

Recently, it has been shown that neural networks not only approximate the ground-state wave functions of a single molecular system well but can also generalize to multiple geometries. While such generalization significantly speeds up…

Machine Learning · Computer Science 2023-03-07 Nicholas Gao , Stephan Günnemann

Deep learning, as a highly efficient method for metasurface inverse design, commonly use simulation data to train deep neural networks (DNNs) that can map desired functionalities to proper metasurface designs. However, the assumptions and…

Signal Processing · Electrical Eng. & Systems 2023-08-07 Jingxin Zhang , Jiawei Xi , Peixing Li , Ray C. C. Cheung , Alex M. H. Wong , Jensen Li

Machine learning of multi-dimensional potential energy surfaces, from purely ab initio datasets, has seen substantial progress in the past years. Gaussian processes, a popular regression method, have been very successful at producing…

Chemical Physics · Physics 2023-01-11 Fabio E. A. Albertani , Alex J. W. Thom

Recent advances in machine-learning interatomic potentials have enabled the efficient modeling of complex atomistic systems with an accuracy that is comparable to that of conventional quantum mechanics based methods. At the same time, the…

Materials Science · Physics 2021-05-06 April M. Miksch , Tobias Morawietz , Johannes Kästner , Alexander Urban , Nongnuch Artrith

Molecular Dynamics (MD) simulation is a powerful tool for understanding the dynamics and structure of matter. Since the resolution of MD is atomic-scale, achieving long time-scale simulations with femtosecond integration is very expensive.…

Machine Learning · Computer Science 2022-04-27 Zijie Li , Kazem Meidani , Prakarsh Yadav , Amir Barati Farimani

Simulating interactions between non-spherical colloidal particles is computationally challenging due to the complex dependency of forces and energies on their geometry. We introduce and evaluate both descriptor-based and end-to-end models…

Soft Condensed Matter · Physics 2025-09-22 B. Rusen Argun , Antonia Statt
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