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The left atrium (LA) plays a pivotal role in modulating left ventricular filling, but our comprehension of its hemodynamics is significantly limited by the constraints of conventional ultrasound analysis. 4D flow magnetic resonance imaging…

Image-based patient-specific simulation of left ventricular (LV) mechanics is valuable for understanding cardiac function and supporting clinical intervention planning, but conventional finite-element analysis (FEA) is computationally…

Machine Learning · Computer Science 2026-02-09 Siyu Mu , Wei Xuan Chan , Choon Hwai Yap

PediaFlow is a miniature mixed-flow ventricular assist device for neonates and toddlers. PediaFlow has a fully magnetically levitated rotor which improves biocompatibility, but the increased length of the rotor creates a long annular…

Fluid Dynamics · Physics 2022-11-09 Mansur Zhussupbekov , Greg W Burgreen , Jeongho Kim , James F Antaki

We numerically investigate the role of mechanical stress in modifying the conductivity properties of the cardiac tissue and its impact in computational models for cardiac electromechanics. We follow a theoretical framework recently proposed…

Tissues and Organs · Quantitative Biology 2019-05-02 A. Loppini , A. Gizzi , R. Ruiz Baier , C. Cherubini , F. Fenton , S. Filippi

Computational hemodynamics is becoming an increasingly important tool in clinical applications and surgical procedures involving the cardiovascular system. Aim of this review is to provide a compact summary of state of the art 0D-1D…

Medical Physics · Physics 2022-01-03 Stefania Scarsoglio , Luca Ridolfi

In electromagnetic analysis, the finite element and boundary element methods jointly known as 'FEM-BEM coupling' is applied for numerically solving levitation problem based on eddy current. The main focus behind this coupled analysis method…

Numerical Analysis · Mathematics 2021-08-24 Sayan Sarkar , Amit Jena , Mashuq un Nabi

Computational Fluid Dynamics (CFD) simulation by the numerical solution of the Navier-Stokes equations is an essential tool in a wide range of applications from engineering design to climate modeling. However, the computational cost and…

Computational Physics · Physics 2021-11-29 Mateus Dias Ribeiro , Abdul Rehman , Sheraz Ahmed , Andreas Dengel

The finite element simulation of dynamic wetting phenomena, requiring the computation of flow in a domain confined by intersecting a liquid-fluid free surface and a liquid-solid interface, with the three-phase contact line moving across the…

Computational Physics · Physics 2012-02-20 J. E. Sprittles , Y. D. Shikhmurzaev

The aorta is the body's largest arterial vessel, serving as the primary pathway for oxygenated blood within the systemic circulation. Aortic aneurysms consistently rank among the top twenty causes of mortality in the United States. Thoracic…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Jiasong Chen , Linchen Qian , Ruonan Gong , Christina Sun , Tongran Qin , Thuy Pham , Caitlin Martin , Mohammad Zafar , John Elefteriades , Wei Sun , Liang Liang

Physics-based computer models based on numerical solution of the governing equations generally cannot make rapid predictions, which in turn, limits their applications in the clinic. To address this issue, we developed a physics-informed…

Computational Engineering, Finance, and Science · Computer Science 2024-10-14 Ehsan Naghavi , Haifeng Wang , Lei Fan , Jenny S. Choy , Ghassan Kassab , Seungik Baek , Lik-Chuan Lee

The numerical tools to simulate the bidomain model in cardiac electrophysiology are constantly developing due to the great clinical interest and scientific advances in mathematical models and computational power. The bidomain model consists…

Numerical Analysis · Mathematics 2025-11-03 Gopika P B , Peter Bastian , Nagaiah Chamakuri

Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Although HLHS patients typically…

Medical Physics · Physics 2025-11-06 Yaqi Li , Justin D. Weigand , Charles Puelz , Mette S. Olufsen , Alyssa Taylor-LaPole

Functionally significant coronary artery disease (CAD) is caused by plaque buildup in the coronary arteries, potentially leading to narrowing of the arterial lumen, i.e. coronary stenosis, that significantly obstructs blood flow to the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Nils Hampe , Sanne G. M. van Velzen , Jean-Paul Aben , Carlos Collet , Ivana Išgum

Aerospace design is increasingly incorporating Design Under Uncertainty based approaches to lead to more robust and reliable optimal designs. These approaches require dependable estimates of uncertainty in simulations for their success. The…

Fluid Dynamics · Physics 2024-02-28 Marcel Matha , Christian Morsbach

The traditional finite-difference time-domain (FDTD) method is constrained by the Courant-Friedrich-Levy (CFL) condition and suffers from the notorious staircase error in electromagnetic simulations. This paper proposes a three-dimensional…

Computational Engineering, Finance, and Science · Computer Science 2021-12-08 Hanhong Liu , Xiaoying Zhao , Xiang-Hua Wang , Shunchuan Yang , Zhizhang , Chen

Cardiovascular hemodynamic fields provide valuable medical decision markers for coronary artery disease. Computational fluid dynamics (CFD) is the gold standard for accurate, non-invasive evaluation of these quantities in silico. In this…

Quantitative Methods · Quantitative Biology 2025-08-27 Julian Suk , Guido Nannini , Patryk Rygiel , Christoph Brune , Gianluca Pontone , Alberto Redaelli , Jelmer M. Wolterink

Computational Fluid Dynamics (CFD) is the main approach to analyzing flow field. However, the convergence and accuracy depend largely on mathematical models of flow, numerical methods, and time consumption. Deep learning-based analysis of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Chang Liu

The electrocardiogram (ECG) is modulated by torso-heart anatomy, and this challenges patients' diagnosis and risk stratification. This study aims to quantify how torso-heart anatomical factors affect sex-differences in ECG biomarkers in…

Computational fluid dynamics (CFD) simulations, a critical tool in various engineering applications, often require significant time and compute power to predict flow properties. The high computational cost associated with CFD simulations…

Machine Learning · Computer Science 2022-05-18 Tongtao Zhang , Biswadip Dey , Krishna Veeraraghavan , Harshad Kulkarni , Amit Chakraborty

Computational fluid dynamics (CFD) in many cases requires designing 3D models manually, which is a tedious task that requires specific skills. In this paper, we present a novel method for performing CFD directly on scanned 3D point clouds.…