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Differential analysis is a routine procedure in the statistical analysis toolbox across many applied fields, including quantitative proteomics, the main illustration of the present paper. The state-of-the-art limma approach uses a…

Methodology · Statistics 2025-12-12 Marie Chion , Arthur Leroy

Selective inference methods are developed for group lasso estimators for use with a wide class of distributions and loss functions. The method includes the use of exponential family distributions, as well as quasi-likelihood modeling for…

Methodology · Statistics 2024-03-28 Yiling Huang , Sarah Pirenne , Snigdha Panigrahi , Gerda Claeskens

The organization and mining of malaria genomic and post-genomic data is highly motivated by the necessity to predict and characterize new biological targets and new drugs. Biological targets are sought in a biological space designed from…

Quantitative Methods · Quantitative Biology 2016-08-16 L. -M. Birkholtz , O. Bastien , G. Wells , D. Grando , F. Joubert , V. Kasam , M. Zimmermann , P. Ortet , N. Jacq , S. Roy , M. Hoffmann-Apitius , V. Breton , A. I. Louw , E. Maréchal

In life sciences, the experts generally use empirical knowledge to recode variables, choose interactions and perform selection by classical approach. The aim of this work is to perform automatic learning algorithm for variables selection…

Machine Learning · Statistics 2015-11-05 Bienvenue Kouwayè , Noël Fonton , Fabrice Rossi

Consider a multinomial regression model where the response, which indicates a unit's membership in one of several possible unordered classes, is associated with a set of predictor variables. Such models typically involve a matrix of…

Applications · Statistics 2009-01-28 Paul Gustafson , Geneviève Lefebvre

Machine learning models are often used to inform real world risk assessment tasks: predicting consumer default risk, predicting whether a person suffers from a serious illness, or predicting a person's risk to appear in court. Given…

Machine Learning · Computer Science 2023-06-27 Jamelle Watson-Daniels , David C. Parkes , Berk Ustun

We consider a discrete latent variable model for two-way data arrays, which allows one to simultaneously produce clusters along one of the data dimensions (e.g. exchangeable observational units or features) and contiguous groups, or…

Joint models for longitudinal and survival data have gained a lot of attention in recent years, with the development of myriad extensions to the basic model, including those which allow for multivariate longitudinal data, competing risks…

Methodology · Statistics 2020-03-09 Katya Mauff , Ewout Steyerberg , Isabella Kardys , Eric Boersma , Dimitris Rizopoulos

Statistical analysis based on quantile regression methods is more comprehensive, flexible, and less sensitive to outliers when compared to mean regression methods. When the link between different diseases are of interest, joint disease…

Methodology · Statistics 2022-02-01 Hanan Alahmadi , Håvard Rue , Janet van Niekerk

Membership inference attacks (MIAs) attempt to predict whether a particular datapoint is a member of a target model's training data. Despite extensive research on traditional machine learning models, there has been limited work studying MIA…

Joint modeling of multiview graphs with a common set of nodes between views and auxiliary predictors is an essential, yet less explored, area in statistical methodology. Traditional approaches often treat graphs in different views as…

Methodology · Statistics 2026-03-24 Sharmistha Guha , Jose Rodriguez-Acosta , Ivo Dinov

Analysing multiple evidence sources is often feasible only via a modular approach, with separate submodels specified for smaller components of the available evidence. Here we introduce a generic framework that enables fully Bayesian…

Determining whether a dataset was part of a machine learning model's training data pool can reveal privacy vulnerabilities, a challenge often addressed through membership inference attacks (MIAs). Traditional MIAs typically require access…

Machine Learning · Computer Science 2025-06-03 Yongchao Huang

The analysis of large scale medical claims data has the potential to improve quality of care by generating insights which can be used to create tailored medical programs. In particular, the multivariate probit model can be used to…

Analyzing multilayer networks is central to understanding complex relational measurements collected across multiple conditions or over time. A pivotal task in this setting is to quantify uncertainty in community structure while…

Methodology · Statistics 2025-12-10 Fangzheng Xie , Hsin-Hsiung Huang

Current machine learning methods for medical image analysis primarily focus on developing models tailored for their specific tasks, utilizing data within their target domain. These specialized models tend to be data-hungry and often exhibit…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Ece Ozkan , Xavier Boix

Many scientific applications involve mixed spatially indexed outcomes of heterogeneous types that are driven by shared latent mechanisms. Modeling such data is challenging due to complex, nonlinear, and potentially nonstationary spatial…

Methodology · Statistics 2026-03-10 Yeseul Jeon , Kyeong Eun Lee , Joon Jin Song

We develop methods for analyzing discrete multivariate longitudinal data and apply them to functional disability data on the U.S. elderly population from the National Long Term Care Survey (NLTCS), 1982-2004. Our models build on a Mixed…

Applications · Statistics 2015-03-05 Daniel Manrique-Vallier

We present the multidimensional membership mixture (M3) models where every dimension of the membership represents an independent mixture model and each data point is generated from the selected mixture components jointly. This is helpful…

Machine Learning · Computer Science 2012-08-03 Yun Jiang , Marcus Lim , Ashutosh Saxena

Recent work on overfitting Bayesian mixtures of distributions offers a powerful framework for clustering multivariate data using a latent Gaussian model which resembles the factor analysis model. The flexibility provided by overfitting…

Methodology · Statistics 2019-08-29 Panagiotis Papastamoulis
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