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In multicellular organisms, relations among parts and between parts and the whole are contextual and interdependent. These organisms and their cells are ontogenetically linked: an organism starts as a cell that divides producing…

Other Quantitative Biology · Quantitative Biology 2017-09-15 Maël Montévil , Lucia Speroni , Carlos Sonnenschein , Ana M. Soto

Computer vision plays a major role in the robotics industry, where vision data is frequently used for navigation and high-level decision making. Although there is significant research in algorithms and functional requirements, there is a…

Computer Vision and Pattern Recognition · Computer Science 2014-11-03 Shannon Fenn , Alexandre Mendes , David Budden

Effective human-machine collaboration can significantly improve many learning and planning strategies for information gathering via fusion of 'hard' and 'soft' data originating from machine and human sensors, respectively. However,…

Human-Computer Interaction · Computer Science 2015-12-24 Kin Gwn Lore , Nicholas Sweet , Kundan Kumar , Nisar Ahmed , Soumik Sarkar

We model human and animal learning by computing with high-dimensional vectors (H = 10,000 for example). The architecture resembles traditional (von Neumann) computing with numbers, but the instructions refer to vectors and operate on them…

Machine Learning · Computer Science 2026-02-24 Pentti Kanerva

Deep generative models have been recently extended to synthesizing 3D digital humans. However, previous approaches treat clothed humans as a single chunk of geometry without considering the compositionality of clothing and accessories. As a…

Computer Vision and Pattern Recognition · Computer Science 2023-05-30 Taeksoo Kim , Shunsuke Saito , Hanbyul Joo

The applicability of computational and dynamical systems models to organisms is scrutinized, using examples from developmental biology and cognition. Developmental morphogenesis is dependent on the inherent material properties of developing…

Neurons and Cognition · Quantitative Biology 2023-10-24 Stuart A. Newman

Integrative biological simulations have a varied and controversial history in the biological sciences. From computational models of organelles, cells, and simple organisms, to physiological models of tissues, organ systems, and ecosystems,…

Quantitative Methods · Quantitative Biology 2017-12-06 Gopal P. Sarma , Victor Faundez

Living systems, from single cells to higher vertebrates, receive a continuous stream of non-stationary inputs that they sense, e.g., via cell surface receptors or sensory organs. Integrating these time-varying, multi-sensory, and often…

Other Quantitative Biology · Quantitative Biology 2024-04-17 Daniel Koch , Akhilesh Nandan , Gayathri Ramesan , Aneta Koseska

Numerical end-to-end simulation in Adaptive Optics (AO) is a key tool in the development of complex systems, from the initial design to the commissioning phase. Based on our previous experience with PASSATA, we decided to develop a new AO…

Instrumentation and Methods for Astrophysics · Physics 2026-02-09 Fabio Rossi , Alfio Puglisi , Guido Agapito

While deep learning models have shown strong performance in simulating neural responses, they often fail to clearly separate stable visual encoding from condition-specific adaptation, which limits their ability to generalize across stimuli…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Qi Xu , Shuai Gong , Xuming Ran , Haihua Luo , Yangfan Hu

An in-vitro cell culture system is used for biological discoveries and hypothesis-driven research on a particular cell type to understand mechanistic or test pharmaceutical drugs. Conventional in-vitro cultures have been applied to primary…

Image and Video Processing · Electrical Eng. & Systems 2023-01-09 Alireza Ranjbaran , Azadeh Nazemi

The physical interpretation of the functioning of the adaptive immune system, which has been thoroughly characterized on genetic and molecular levels, provides a unique opportunity to define an adaptive self-organizing biological system in…

Molecular Networks · Quantitative Biology 2023-05-19 Jozsef Prechl

In recent years, the transformer architecture has become the de facto standard for machine learning algorithms applied to natural language processing and computer vision. Despite notable evidence of successful deployment of this…

Robotics · Computer Science 2024-08-13 Carmelo Sferrazza , Dun-Ming Huang , Fangchen Liu , Jongmin Lee , Pieter Abbeel

It has been increasingly recognized that effective human-AI co-creation requires more than prompts and results, but an environment with empowering structures that facilitate exploration, planning, iteration, as well as control and…

Human-Computer Interaction · Computer Science 2025-03-07 Yining Cao , Yiyi Huang , Anh Truong , Hijung Valentina Shin , Haijun Xia

This paper presents Virtual Simulation Objects (VSO) concept which forms theoretical basis for building tools and framework that is developed for system-level simulations using existing software modules available within…

Systems and Control · Computer Science 2016-03-21 Sergey V. Kovalchuk , Pavel A. Smirnov , Sergey S. Kosukhin , Alexander V. Boukhanovsky

In biomechanical systems, observable performance is often used as a proxy for underlying system organization. However, this assumption implicitly presumes a correspondence between output metrics and internal system states that may not hold…

Machine Learning · Computer Science 2026-05-04 Jacques Raynal , Pierre Slangen , Jacques Margerit

For the study of complex synthetic and biological molecular systems by computer simulations one is still restricted to simple model systems or to by far too small time scales. To overcome this problem multiscale techniques are being…

Statistical Mechanics · Physics 2007-05-23 Matej Praprotnik , Kurt Kremer , Luigi Delle Site

One of the strength of Virtual Organisations is their ability to dynamically and rapidly adapt in response to changing environmental conditions. Dynamic adaptability has been studied in other system areas as well and system management…

Multiagent Systems · Computer Science 2012-04-30 Stephan Reiff-Marganiec

Soft growing robots, commonly referred to as vine robots, have demonstrated remarkable ability to interact safely and robustly with unstructured and dynamic environments. It is therefore natural to exploit contact with the environment for…

Robotics · Computer Science 2026-02-10 Yitian Gao , Lucas Chen , Priyanka Bhovad , Sicheng Wang , Zachary Kingston , Laura H. Blumenschein

In a complex system, the individual components are neither so tightly coupled or correlated that they can all be treated as a single unit, nor so uncorrelated that they can be approximated as independent entities. Instead, patterns of…

Populations and Evolution · Quantitative Biology 2015-09-15 Blake C. Stacey