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In this study, we develop a physics-informed deep learning-based method to synthesize multiple brain magnetic resonance imaging (MRI) contrasts from a single five-minute acquisition and investigate its ability to generalize to arbitrary…

Magnetic Resonance (MR) imaging allows the acquisition of images with different contrast properties depending on the acquisition protocol and the magnetic properties of tissues. Many MR brain image processing techniques, such as tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-04-18 Samuel Remedios , Dzung L. Pham , John A. Butman , Snehashis Roy

Brain segmentation from neonatal MRI images is a very challenging task due to large changes in the shape of cerebral structures and variations in signal intensities reflecting the gestational process. In this context, there is a clear need…

Machine Learning · Statistics 2023-09-12 R Valabregue , F Girka , A Pron , F Rousseau , G Auzias

Purpose: Visualization of subcortical gray matter is essential in neuroscience and clinical practice, particularly for disease understanding and surgical planning.While multi-inversion time (multi-TI) T$_1$-weighted (T$_1$-w) magnetic…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Savannah P. Hays , Lianrui Zuo , Anqi Feng , Yihao Liu , Blake E. Dewey , Jiachen Zhuo , Ellen M. Mowry , Scott D. Newsome , Jerry L. Prince , Aaron Carass

Magnetic Resonance Fingerprinting (MRF) is an efficient quantitative MRI technique that can extract important tissue and system parameters such as T1, T2, B0, and B1 from a single scan. This property also makes it attractive for…

Image and Video Processing · Electrical Eng. & Systems 2022-12-22 Ke Wang , Mariya Doneva , Jakob Meineke , Thomas Amthor , Ekin Karasan , Fei Tan , Jonathan I. Tamir , Stella X. Yu , Michael Lustig

Purpose A Magnetic Resonance Imaging (MRI) exam typically consists of several sequences that yield different image contrasts. Each sequence is parameterized through multiple acquisition parameters that influence image contrast,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Jonas Denck , Jens Guehring , Andreas Maier , Eva Rothgang

Multiple Sclerosis (MS) is a chronic progressive neurological disease characterized by the development of lesions in the white matter of the brain. T2-fluid-attenuated inversion recovery (FLAIR) brain magnetic resonance imaging (MRI)…

Image and Video Processing · Electrical Eng. & Systems 2022-09-12 Jueqi Wang , Derek Berger , Erin Mazerolle , Othman Soufan , Jacob Levman

Acquiring images of the same anatomy with multiple different contrasts increases the diversity of diagnostic information available in an MR exam. Yet, scan time limitations may prohibit acquisition of certain contrasts, and images for some…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Salman Ul Hassan Dar , Mahmut Yurt , Levent Karacan , Aykut Erdem , Erkut Erdem , Tolga Çukur

A Magnetic Resonance Imaging (MRI) exam typically consists of the acquisition of multiple MR pulse sequences, which are required for a reliable diagnosis. Each sequence can be parameterized through multiple acquisition parameters affecting…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Jonas Denck , Jens Guehring , Andreas Maier , Eva Rothgang

Self-supervised image denoising techniques emerged as convenient methods that allow training denoising models without requiring ground-truth noise-free data. Existing methods usually optimize loss metrics that are calculated from multiple…

Purpose: To provide a simulation framework for routine neuroimaging test data, which allows for "stress testing" of deep segmentation networks against acquisition shifts that commonly occur in clinical practice for T2 weighted (T2w) fluid…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Christiane Posselt , Mehmet Yigit Avci , Mehmet Yigitsoy , Patrick Schünke , Christoph Kolbitsch , Tobias Schäffter , Stefanie Remmele

MRI images of the same subject in different contrasts contain shared information, such as the anatomical structure. Utilizing the redundant information amongst the contrasts to sub-sample and faithfully reconstruct multi-contrast images…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Xinwen Liu , Jing Wang , Fangfang Tang , Shekhar S. Chandra , Feng Liu , Stuart Crozier

Multi contrast MRI synthesis is inherently challenging due to the complex and nonlinear relationships among different contrasts. Each MRI contrast highlights unique tissue properties, but their complementary information is difficult to…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Sanuwani Dayarathna , Himashi Peiris , Kh Tohidul Islam , Tien-Tsin Wong , Zhaolin Chen

Microscopy images are crucial for life science research, allowing detailed inspection and characterization of cellular and tissue-level structures and functions. However, microscopy data are unavoidably affected by image degradations, such…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Nuno Pimpão Martins , Yannis Kalaidzidis , Marino Zerial , Florian Jug

Modern vision models excel at general purpose downstream tasks. It is unclear, however, how they may be used for personalized vision tasks, which are both fine-grained and data-scarce. Recent works have successfully applied synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Shobhita Sundaram , Julia Chae , Yonglong Tian , Sara Beery , Phillip Isola

Head motion is an omnipresent confounder of magnetic resonance image (MRI) analyses as it systematically affects morphometric measurements, even when visual quality control is performed. In order to estimate subtle head motion, that remains…

Image and Video Processing · Electrical Eng. & Systems 2026-04-03 Clemens Pollak , David Kügler , Martin Reuter

Clinical application of high-resolution diffusion MRI is hindered by hardware limitations and prohibitive scan times, motivating computational super-resolution. This study investigates the efficacy of a feature-based loss function in…

Image and Video Processing · Electrical Eng. & Systems 2026-05-18 David Lohr , Rene Werner

Magnetic Resonance Imaging (MRI) enables the acquisition of multiple image contrasts, such as T1-weighted (T1w) and T2-weighted (T2w) scans, each offering distinct diagnostic insights. However, acquiring all desired modalities increases…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Andrea Moschetto , Lemuel Puglisi , Alec Sargood , Pierluigi Dell'Acqua , Francesco Guarnera , Sebastiano Battiato , Daniele Ravì

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Lakshmi Nair

Deep learning approaches to the segmentation of magnetic resonance images have shown significant promise in automating the quantitative analysis of brain images. However, a continuing challenge has been its sensitivity to the variability of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Dzung L. Pham , Yi-Yu Chou , Blake E. Dewey , Daniel S. Reich , John A. Butman , Snehashis Roy
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