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Motivated by the increasing use of and rapid changes in array technologies, we consider the prediction problem of fitting a linear regression relating a continuous outcome $Y$ to a large number of covariates $\mathbf {X}$, for example,…

Applications · Statistics 2014-01-13 Philip S. Boonstra , Bhramar Mukherjee , Jeremy M. G. Taylor

The Cox regression, a semi-parametric method of survival analysis, is extremely popular in biomedical applications. The proportional hazards assumption is a key requirement in the Cox model. To accommodate non-proportional hazards, we…

Methodology · Statistics 2022-06-13 Alexander Begun , Elena Kulinskaya

This work is concerned with the estimation of multidimensional regression and the asymptotic behaviour of the test involved in selecting models. The main problem with such models is that we need to know the covariance matrix of the noise to…

Statistics Theory · Mathematics 2008-02-20 Joseph Rynkiewicz

This paper deals with a situation when one is interested in the dependence structure of a multidimensional response variable in the presence of a multivariate covariate. It is assumed that the covariate affects only the marginal…

Statistics Theory · Mathematics 2019-03-12 Marek Omelka , Šárka Hudecová , Natalie Neumeyer

While there are many well-developed data science methods for classification and regression, there are relatively few methods for working with right-censored data. Here, we present "survival stacking": a method for casting survival analysis…

Methodology · Statistics 2021-07-29 Erin Craig , Chenyang Zhong , Robert Tibshirani

Relative survival methodology deals with a competing risks survival model where the cause of death is unknown. This lack of information occurs regularly in population-based cancer studies. Non-parametric estimation of the net survival is…

Statistics Theory · Mathematics 2025-02-14 Oskar Laverny , Nathalie Grafféo , Roch Giorgi

This article analyzes the problem of estimating the time until an event occurs, also known as survival modeling. We observe through substantial experiments on large real-world datasets and use-cases that populations are largely…

Machine Learning · Computer Science 2019-05-13 David Hubbard , Benoit Rostykus , Yves Raimond , Tony Jebara

With known cause of death (CoD), competing risk survival methods are applicable in estimating disease-specific survival. Relative survival analysis may be used to estimate disease-specific survival when cause of death is either unknown or…

Methodology · Statistics 2021-12-10 Reuben Adatorwovor , Aurelien Latouche , Jason P. Fine

Binomial data with unknown sizes often appear in biological and medical sciences and are usually overdispersed. All previous methods used parametric models and only considered overdispersion due to the variation of sizes. The proposed…

Statistics Theory · Mathematics 2007-06-13 Wei Zhang

This paper studies identification and estimation in semiparametric logit models when social networks are endogenous. In many applications, unobserved individual traits shape both the outcome of interest and the formation of social ties, so…

Econometrics · Economics 2026-03-13 Brice Romuald Gueyap Kounga

In this paper we investigate the flexibility of matrix distributions for the modeling of mortality. Starting from a simple Gompertz law, we show how the introduction of matrix-valued parameters via inhomogeneous phase-type distributions can…

Methodology · Statistics 2022-08-03 Hansjoerg Albrecher , Martin Bladt , Mogens Bladt , Jorge Yslas

In survival analysis it often happens that some subjects under study do not experience the event of interest; they are considered to be `cured'. The population is thus a mixture of two subpopulations: the one of cured subjects, and the one…

Statistics Theory · Mathematics 2017-01-16 Valentin Patilea , Ingrid Van Keilegom

Missing values in datasets are common in applied statistics. For regression problems, theoretical work thus far has largely considered the issue of missing covariates as distinct from missing responses. However, in practice, many datasets…

Statistics Theory · Mathematics 2026-02-17 Benedict M. Risebrow , Thomas B. Berrett

We propose a versatile framework for survival analysis that combines advanced concepts from statistics with deep learning. The presented framework is based on piecewise exponential models and thereby supports various survival tasks, such as…

Machine Learning · Computer Science 2021-03-02 Philipp Kopper , Sebastian Pölsterl , Christian Wachinger , Bernd Bischl , Andreas Bender , David Rügamer

Introduction: Modelling of relative treatment effects is an important aspect to consider when extrapolating the long-term survival outcomes of treatments. Flexible parametric models offer the ability to accurately model the observed data,…

Methodology · Statistics 2024-01-02 Philip Cooney , Arthur White

Semi-competing risks refer to the setting where primary scientific interest lies in estimation and inference with respect to a non-terminal event, the occurrence of which is subject to a terminal event. In this paper, we present the R…

Computation · Statistics 2018-04-06 Danilo Alvares , Sebastien Haneuse , Catherine Lee , Kyu Ha Lee

This paper develops a new approach to post-selection inference for screening high-dimensional predictors of survival outcomes. Post-selection inference for right-censored outcome data has been investigated in the literature, but much…

Methodology · Statistics 2021-12-22 Tzu-Jung Huang , Alex Luedtke , Ian W. McKeague

In fitting a mixture of linear regression models, normal assumption is traditionally used to model the error and then regression parameters are estimated by the maximum likelihood estimators (MLE). This procedure is not valid if the normal…

Methodology · Statistics 2018-11-06 Yanyuan Ma , Shaoli Wang , Lin Xu , Weixin Yao

Time-to-event semi-competing risk endpoints may be correlated when both events are occurring on the same individual. These events and the association between them may also be influenced by individual characteristics. In this paper, we…

Methodology · Statistics 2023-04-07 Yinghui Wei , Malgorzata Wojtys , Lexy Sorrell , Peter Rowe

We develop a multivariate cure survival model to estimate lifetime patterns of colorectal cancer screening. Screening data cover long periods of time, with sparse observations for each person. Some events may occur before the study begins…

Methodology · Statistics 2015-09-16 Yolanda Hagar , Danielle Harvey , Laurel Beckett