Related papers: Further Thoughts on Abnormal Chromatin Configurati…
I give a brief overview of our current understanding of the internal partonic 3D structure of nucleons in momentum space. I discuss some recent extractions of transverse-momentum-dependent distributions for quarks, whose analyses in the…
The remarkable range of biological forms in and around us, such as the undulating shape of a leaf or flower in the garden, the coils in our gut, or the folds in our brain, raise a number of questions at the interface of biology, physics and…
In the last decades, the number of exotic candidates which are beyond the conventional quark model has grown dramatically. At the same time, numerous theoretical interpretations, such as tetraquark, hybrid, hadroquarkonium and hadronic…
The cell cycle is tightly regulated by cyclins and their catalytic moieties, the cyclin-dependent kinases (CDKs). Cyclin D1, in association with CDK4/6, acts as a mitogenic sensor and integrates extracellular mitogenic signals and cell…
We explore in this paper some orthogonal polynomials which are naturally associated to certain families of coherent states, often referred to as nonlinear coherent states in the quantum optics literature. Some examples turn out to be known…
In this paper, we study a well-posedness problem on a new mathematical model for cancer invasion within the plasminogen activation system, which explicitly incorporates cooperation with host normal cells. Key biological…
We report the results of an experimental and theoretical study of the electronic and structural properties of a key eumelanin precursor - 5,6,-dihydroxyindole-2-carboxylic acid (DHICA) and its dimeric forms. We have used optical…
Progress in high-resolution x-ray microtomography has provided us with a practical approach to determining three-dimensional (3D) structures of opaque samples at micrometer to submicrometer resolution. In this review, we give an…
Cancer is a heterogeneous disease with different combinations of genetic and epigenetic alterations driving the development of cancer in different individuals. While these alterations are believed to converge on genes in key cellular…
The eigenmodes of unstable canonical optical resonators possess fractal structure in their transverse intensity cross-sections [Karman et al., Nature 402, 138 (1999)]. In one particular plane, the magnified self-conjugate plane, this…
It has previously been shown that 2D spectral mammography can be used to discriminate between (likely benign) cystic and (potentially malignant) solid lesions in order to reduce unnecessary recalls in mammography. One limitation of the…
Carcinogenesis is a complex process that involves dynamically inter-connected modular sub-networks that evolve under the influence of micro-environmentally induced perturbations, in non-random, pseudo-Markov chain processes. An appropriate…
Many organs of higher organisms are heavily branched structures and arise by an at first sight similar process of branching morphogenesis. Yet the regulatory components and local interactions that have been identified differ greatly in…
The pathogenesis of cancer in human is still poorly understood. With the rapid development of high-throughput sequencing technologies, huge volumes of cancer genomics data have been generated. Deciphering those data poses great…
Motivation: The three-dimensional (3D) organization of the genome plays a critical role in regulating gene expression and maintaining cellular homeostasis. Disruptions in this spatial organization can result in abnormal chromatin…
We obtain possibly valuable information about the orientation-tuning of phase diagram of superdense nuclear matter at high fermion as well as boson number density but low temperature, which is not accessible to relativistic heavy ion…
We review recent work on the phase structure of QCD at very high baryon density. We introduce the phenomenon of color superconductivity and discuss the use of weak coupling methods. We study the phase structure as a function of the number…
Biological materials are self-assembled with near-atomic precision in living cells, whereas synthetic 3D structures generally lack such precision and controllability. Recently, DNA nanotechnology, especially DNA origami technology, has been…
To support comparative genomics, population genetics, and medical genetics, we propose that a reference genome should come with a scheme for mapping each base in any DNA string to a position in that reference genome. We refer to a…
An analytical model for the evolution of the boundary of the new phase in transformations ruled by nucleation and growth is presented. Both homogeneous and heterogeneous nucleation have been considered: The former includes transformations…