English
Related papers

Related papers: GAN-based Virtual Re-Staining: A Promising Solutio…

200 papers

Performance of data-driven network for tumor classification varies with stain-style of histopathological images. This article proposes the stain-style transfer (SST) model based on conditional generative adversarial networks (GANs) which is…

Computer Vision and Pattern Recognition · Computer Science 2018-12-21 Hyungjoo Cho , Sungbin Lim , Gunho Choi , Hyunseok Min

This paper addresses the problem of quantifying biomarkers in multi-stained tissues, based on color and spatial information. A deep learning based method that can automatically localize and quantify the cells expressing biomarker(s) in a…

Tissues and Organs · Quantitative Biology 2017-01-02 Fahime Sheikhzadeh , Martial Guillaud , Rabab K. Ward

Immunohistochemistry (IHC) staining plays a significant role in the evaluation of diseases such as breast cancer. The H&E-to-IHC transformation based on generative models provides a simple and cost-effective method for obtaining IHC images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-28 Yifan Jia , Xingda Yu , Zhengyang Ji , Songning Lai , Yutao Yue

The advent of Generative Adversarial Networks (GANs) has brought about completely novel ways of transforming and manipulating pixels in digital images. GAN based techniques such as Image-to-Image translations, DeepFakes, and other automated…

Computer Vision and Pattern Recognition · Computer Science 2019-10-04 Lakshmanan Nataraj , Tajuddin Manhar Mohammed , Shivkumar Chandrasekaran , Arjuna Flenner , Jawadul H. Bappy , Amit K. Roy-Chowdhury , B. S. Manjunath

Generative Adversarial Networks (GANs) have facilitated a new direction to tackle the image-to-image transformation problem. Different GANs use generator and discriminator networks with different losses in the objective function. Still…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Kancharagunta Kishan Babu , Shiv Ram Dubey

For invasive breast cancer, immunohistochemical (IHC) techniques are often used to detect the expression level of human epidermal growth factor receptor-2 (HER2) in breast tissue to formulate a precise treatment plan. From the perspective…

Prostate cancer (PCa) is graded by pathologists by examining the architectural pattern of cancerous epithelial tissue on hematoxylin and eosin (H&E) stained slides. Given the importance of gland morphology, automatically differentiating…

Cervical cancer will cause 460 000 deaths per year by 2040, approximately 90% are Sub-Saharan African women. A constantly increasing incidence in Africa making cervical cancer a priority by the World Health Organization (WHO) in terms of…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Ferdaous Idlahcen , Mohammed Majid Himmi , Abdelhak Mahmoudi

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

Image and Video Processing · Electrical Eng. & Systems 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

Computational pathology has made significant progress in recent years, fueling advances in both fundamental disease understanding and clinically ready tools. This evolution is driven by the availability of large amounts of digitized slides…

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Color inconsistency is an inevitable challenge in computational pathology, which generally happens because of stain intensity variations or sections scanned by different scanners. It harms the pathological image analysis methods, especially…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Bingchao Zhao , Jiatai Lin , Changhong Liang , Zongjian Yi , Xin Chen , Bingbing Li , Weihao Qiu , Danyi Li , Li Liang , Chu Han , Zaiyi Liu

There is a strong need for automated systems to improve diagnostic quality and reduce the analysis time in histopathology image processing. Automated detection and classification of pathological tissue characteristics with computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2019-11-22 Muhammed Talo

Due to the recent advancements in machine vision, digital pathology has gained significant attention. Histopathology images are distinctly rich in visual information. The tissue glass slide images are utilized for disease diagnosis.…

Image and Video Processing · Electrical Eng. & Systems 2020-11-02 Danial Maleki , Mehdi Afshari , Morteza Babaie , H. R. Tizhoosh

Medical Image Synthesis (MIS) plays an important role in the intelligent medical field, which greatly saves the economic and time costs of medical diagnosis. However, due to the complexity of medical images and similar characteristics of…

Image and Video Processing · Electrical Eng. & Systems 2025-03-07 Zhihan Ju , Wanting Zhou , Longteng Kong , Yu Chen , Yi Li , Zhenan Sun , Caifeng Shan

A key challenge in segmentation in digital histopathology is inter- and intra-stain variations as it reduces model performance. Labelling each stain is expensive and time-consuming so methods using stain transfer via CycleGAN, have been…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Zeeshan Nisar , Friedrich Feuerhake , Thomas Lampert

Histological staining of tissue biopsies, especially hematoxylin and eosin (H&E) staining, serves as the benchmark for disease diagnosis and comprehensive clinical assessment of tissue. However, the process is laborious and time-consuming,…

Computational analysis of multiplexed immunofluorescence histology data is emerging as an important method for understanding the tumour micro-environment in cancer. This work presents HEMIT, a dataset designed for translating Hematoxylin…

Image and Video Processing · Electrical Eng. & Systems 2024-09-30 Chang Bian , Beth Philips , Tim Cootes , Martin Fergie

We propose Mask CycleGAN, a novel architecture for unpaired image domain translation built based on CycleGAN, with an aim to address two issues: 1) unimodality in image translation and 2) lack of interpretability of latent variables. Our…

Machine Learning · Computer Science 2022-05-17 Minfa Wang

Histopathologic Images (HI) are the gold standard for evaluation of some tumors. However, the analysis of such images is challenging even for experienced pathologists, resulting in problems of inter and intra observer. Besides that, the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-18 Jonathan de Matos , Alceu de Souza Britto , Luiz E. S. Oliveira , Alessandro L. Koerich