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Colorectal cancer is a deadly disease that has become increasingly prevalent in recent years. Early detection is crucial for saving lives, but traditional diagnostic methods such as colonoscopy and biopsy have limitations. Colonoscopy…

Machine Learning · Statistics 2023-07-18 Shangqing Tong , Peng Ge , Yanan Jiao , Zhaofu Ma , Ziye Li , Longhai Liu , Feng Gao , Xiaohui Du , Fei Gao

Molecular and genomic properties are critical in selecting cancer treatments to target individual tumors, particularly for immunotherapy. However, the methods to assess such properties are expensive, time-consuming, and often not routinely…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Heather D. Couture

Accurate recurrence risk stratification is crucial for optimizing treatment plans for breast cancer patients. Current prognostic tools like Oncotype DX (ODX) offer valuable genomic insights for HR+/HER2- patients but are limited by cost and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Ziyu Su , Yongxin Guo , Robert Wesolowski , Gary Tozbikian , Nathaniel S. O'Connell , M. Khalid Khan Niazi , Metin N. Gurcan

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

We built a novel Bayesian hierarchical survival model based on the somatic mutation profile of patients across 50 genes and 27 cancer types. The pan-cancer quality allows for the model to "borrow" information across cancer types, motivated…

Quantitative Methods · Quantitative Biology 2019-10-09 Sarah Samorodnitsky , Katherine A. Hoadley , Eric F. Lock

This study investigates the application of quantum neural networks (QNNs) for propensity score estimation to address selection bias in comparing survival outcomes between laparoscopic and open surgical techniques in a cohort of 1177…

Quantum Physics · Physics 2025-06-26 Vojtěch Novák , Ivan Zelinka , Lenka Přibylová , Lubomír Martínek

Lung and colon cancers are predominant contributors to cancer mortality. Early and accurate diagnosis is crucial for effective treatment. By utilizing imaging technology in different image detection, learning models have shown promise in…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Diponkor Bala , S M Rakib Ul Karim , Rownak Ara Rasul

Colorectal cancer is the third most common tumor in men and the second in women, accounting for 10% of all tumors worldwide. It ranks second in cancer-related deaths with 9.4%, following lung cancer. The decrease in mortality rate…

Other Quantitative Biology · Quantitative Biology 2022-09-27 Panagiotis Katrakazas , Aristotelis Ballas , Marco Anisetti , Ilias Spais

Colorectal cancer is a leading cause of death worldwide. However, early diagnosis dramatically increases the chances of survival, for which it is crucial to identify the tumor in the body. Since its imaging uses high-resolution techniques,…

Image and Video Processing · Electrical Eng. & Systems 2021-03-18 Nisarg A. Shah , Divij Gupta , Romil Lodaya , Ujjwal Baid , Sanjay Talbar

Survival prediction for cancer patients is critical for optimal treatment selection and patient management. Current patient survival prediction methods typically extract survival information from patients' clinical record data or biological…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 Amr Hagag , Ahmed Gomaa , Dominik Kornek , Andreas Maier , Rainer Fietkau , Christoph Bert , Florian Putz , Yixing Huang

Surgery planning in patients diagnosed with brain tumor is dependent on their survival prognosis. A poor prognosis might demand for a more aggressive treatment and therapy plan, while a favorable prognosis might enable a less risky surgery…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Sobia Yousaf , Syed Muhammad Anwar , Harish RaviPrakash , Ulas Bagci

Background and Objective: Only about 14 % of eligible EU citizens finally participate in colorectal cancer (CRC) screening programs despite it being the third most common type of cancer worldwide. The development of CRC risk models can…

In many applications, it is important to identify subpopulations that survive longer or shorter than the rest of the population. In medicine, for example, it allows determining which patients benefit from treatment, and in predictive…

Machine Learning · Computer Science 2026-02-26 Mhd Jawad Al Rahwanji , Sascha Xu , Nils Philipp Walter , Jilles Vreeken

Cancer, a leading cause of death globally, occurs due to genomic changes and manifests heterogeneously across patients. To advance research on personalized treatment strategies, the effectiveness of various drugs on cells derived from…

Machine Learning · Computer Science 2024-05-08 Kumar Shubham , Aishwarya Jayagopal , Syed Mohammed Danish , Prathosh AP , Vaibhav Rajan

In this paper we propose a semi-supervised variational autoencoder for classification of overall survival groups from tumor segmentation masks. The model can use the output of any tumor segmentation algorithm, removing all assumptions on…

Computer Vision and Pattern Recognition · Computer Science 2020-11-18 Sveinn Pálsson , Stefano Cerri , Andrea Dittadi , Koen Van Leemput

Clinical risk prediction models often underperform in real-world settings due to poor calibration, limited transportability, and subgroup disparities. These challenges are amplified in high-dimensional multimodal cancer datasets…

Machine Learning · Computer Science 2026-02-26 Toktam Khatibi

Machine learning in medicine leverages the wealth of healthcare data to extract knowledge, facilitate clinical decision-making, and ultimately improve care delivery. However, ML models trained on datasets that lack demographic diversity…

Machine Learning · Computer Science 2021-11-19 Songzi Liu , Yuan Luo

Personalized head and neck cancer therapeutics have greatly improved survival rates for patients, but are often leading to understudied long-lasting symptoms which affect quality of life. Sequential rule mining (SRM) is a promising…

Human-Computer Interaction · Computer Science 2023-09-28 Carla Floricel , Andrew Wentzel , Abdallah Mohamed , C. David Fuller , Guadalupe Canahuate , G. Elisabeta Marai

While the 10-year survival rate for localized prostate cancer patients is very good (>98%), side effects of treatment may limit quality of life significantly. Erectile dysfunction (ED) is a common burden associated with increasing age as…

According to the World Health Organization (WHO), cancer is the second leading cause of death globally. Scientific research on different types of cancers grows at an ever-increasing rate, publishing large volumes of research articles every…

Computation and Language · Computer Science 2023-06-27 G. Jeyakodi , Arkadeep Pal , Debapratim Gupta , K. Sarukeswari , V. Amouda