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The reliable segmentation of retinal vasculature can provide the means to diagnose and monitor the progression of a variety of diseases affecting the blood vessel network, including diabetes and hypertension. We leverage the power of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-23 Ali Hatamizadeh , Hamid Hosseini , Zhengyuan Liu , Steven D. Schwartz , Demetri Terzopoulos

The size- and fluorescence-based sorting of micro- and nano-scale particles suspended in fluid presents a significant and important challenge for both sample analysis and for manufacturing of nanoparticle-based products. Here we demonstrate…

Soft Condensed Matter · Physics 2015-02-16 Sukumar Rajauria , Christopher Axline , Claudia Gottstein , Andrew N. Cleland

Discrete diffusion models (DDMs) have shown powerful generation ability for discrete data modalities like text and molecules. However, their practical application is hindered by inefficient sampling, requiring a large number of sampling…

Machine Learning · Computer Science 2025-09-25 Feiyang Fu , Tongxian Guo , Zhaoqiang Liu

Resilient divertor features connected to open chaotic edge structures in the Helically Symmetric Experiment (HSX) are investigated. For the first time, an expanded vessel wall was considered that would give space for implementation of a…

Plasma Physics · Physics 2025-02-18 K. A. Garcia , A. Bader , D. Boeyaert , A. H. Boozer , H. Frerichs , M. J. Gerard , A. Punjabi , O. Schmitz

The impact of cell segregation and margination in blood disorders on microcirculatory hemodynamics within bifurcated vessels are physiologically significant, yet poorly understood. This study presents a comprehensive computational…

Biological Physics · Physics 2025-01-09 Xiaopo Cheng , Christina Caruso , Wilbur A. Lam , Michael D. Graham

In situ studies under severe plastic deformation at high pressures, employing rotational/shear diamond anvil cells (RDAC), have recently gained much interest in the high-pressure community owing to their potential applications in material…

Materials Science · Physics 2023-12-22 K. K. Pandey , H. K. Poswal

Cellular traction forces are conventionally measured by tracking the displacement of beads or micropillars, an approach fundamentally limited by optical diffraction and the classical Euler-Bernoulli beam assumption, which is accurate only…

Optics · Physics 2026-03-09 Linjie Ma , Bicong Wang , Tai Nam Yip , Yong Hou , Yuan Lin , Zhiqin Chu

Predicting the electrical behavior of the heart, from the cellular scale to the tissue level, relies on the formulation and numerical approximation of coupled nonlinear dynamical systems. These systems describe the cardiac action potential,…

Computational Physics · Physics 2021-01-27 Stefania Fresca , Andrea Manzoni , Luca Dedè , Alfio Quarteroni

While numerous methods achieving remarkable performance exist in the Object Detection literature, addressing data distribution shifts remains challenging. Continual Learning (CL) offers solutions to this issue, enabling models to adapt to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Francesco Pasti , Marina Ceccon , Davide Dalle Pezze , Francesco Paissan , Elisabetta Farella , Gian Antonio Susto , Nicola Bellotto

We present a rigorous procedure to derive coarse-grained red blood cell (RBC) models, which lead to accurate mechanical properties of realistic RBCs. Based on a semi-analytic theory linear and non-linear elastic properties of the RBC…

Cell Behavior · Quantitative Biology 2009-05-04 Dmitry A. Fedosov , Bruce Caswell , George E. Karniadakis

Distributed deep neural networks (DNNs) have become central to modern computer vision, yet their deployment on resource-constrained edge devices remains hindered by substantial parameter counts, computational demands, and the probability of…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-17 Mahadev Sunil Kumar , Arnab Raha , Debayan Das , Gopakumar G , Rounak Chatterjee , Amitava Mukherjee

We numerically investigate the hydrodynamics and membrane dynamics of multicomponent vesicles in two strongly confined geometries. This serves as a simplified model for red blood cells undergoing large deformations while traversing narrow…

Soft Condensed Matter · Physics 2023-08-21 Ashley Gannon , Bryan Quaife , Y. -N. Young

We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far…

Fluid Dynamics · Physics 2017-09-19 S. Quint , A. F. Christ , A. Guckenberger , S. Himbert , L. Kaestner , S. Gekle , C. Wagner

Identification of abnormalities in red blood cells (RBC) is key to diagnosing a range of medical conditions from anaemia to liver disease. Currently this is done manually, a time-consuming and subjective process. This paper presents an…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Annika Wong , Nantheera Anantrasirichai , Thanarat H. Chalidabhongse , Duangdao Palasuwan , Attakorn Palasuwan , David Bull

Eukaryotic cells maintain their inner order by a hectic process of distillation of molecular factors taking place on the surface of their lipid membranes. To understand the properties of this molecular sorting process, a physical model of…

Soft Condensed Matter · Physics 2023-08-16 A. Piras , E. Floris , L. Dall'Asta , A. Gamba

Mechanical and elastic properties of materials are among the most fundamental quantities for many engineering and industrial applications. Here, we present a formulation that is efficient and accurate for calculating the elastic and bending…

Materials Science · Physics 2026-03-23 Changpeng Lin , Samuel Poncé , Francesco Macheda , Francesco Mauri , Nicola Marzari

Extra-large deformations in ultra-soft elastic materials are ubiquitous, yet systematic studies and methods to understand the mechanics of such huge strains are lacking. Here we investigate this complex problem systematically with a simple…

Materials Science · Physics 2017-01-04 Aditi Chakrabarti , Manoj K. Chaudhury , Serge Mora , Yves Pomeau

We develop a theory for distributed branch points and investigate their role in determining the shape and influencing the mechanics of thin hyperbolic objects. We show that branch points are the natural topological defects in hyperbolic…

Differential Geometry · Mathematics 2021-02-03 Toby L. Shearman , Shankar C. Venkataramani

We investigate the deformation of a longitudinally stretched rectangular sheet which is clamped at two opposite boundaries and free otherwise with experiments, numerical analysis and asymptotic analysis of the biharmonic elastic equation…

Soft Condensed Matter · Physics 2018-07-31 Chopin Julien , Panaitescu Andreea , Kudrolli Arshad

Understanding lattice deformations is crucial in determining the properties of nanomaterials, which can become more prominent in future applications ranging from energy harvesting to electronic devices. However, it remains challenging to…

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