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Related papers: Dynamic fluence map sequencing using piecewise lin…

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In this first paper of a two-paper series, we present a method for optimizing the dynamic delivery of fluence maps in radiation therapy. For a given fluence map and a given delivery time, the optimization of the leaf trajectories of a…

Medical Physics · Physics 2016-08-10 David Craft , Marleen Balvert

In this article we provide a method to generate the trade-off between delivery time and fluence map matching quality for volumetric modulated arc therapy (VMAT). At the heart of our method lies a mathematical programming model that, for a…

Medical Physics · Physics 2017-03-08 Marleen Balvert , David Craft

We propose a novel optimization model for volumetric modulated arc therapy (VMAT) planning that directly optimizes deliverable leaf trajectories in the treatment plan optimization problem, and eliminates the need for a separate…

Medical Physics · Physics 2014-03-05 Dávid Papp , Jan Unkelbach

Fluence map optimization for intensity-modulated radiation therapy planning can be formulated as a large-scale inverse problem with competing objectives and constraints associated with the tumors and organs-at-risk. Unfortunately,…

Optimization and Control · Mathematics 2022-02-17 Kelsey Maass , Minsun Kim , Aleksandr Aravkin

Volumetric Modulated Arc Therapy (VMAT) is a cornerstone of modern radiation therapy, enabling highly conformal tumor irradiation and healthy-tissue sparing. Yet, its planning solves inverse and nested optimization for multi-leaf…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Isabella Poles , Simon Arberet , Riqiang Gao , Martin Kraus , Marco D. Santambrogio , Florin C. Ghesu , Ali Kamen , Dorin Comaniciu

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Medical Physics · Physics 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

Volumetric Modulated Arc Therapy (VMAT) revolutionizes cancer treatment by precisely delivering radiation while sparing healthy tissues. Fluence maps generation, crucial in VMAT planning, traditionally involves complex and iterative, and…

Image and Video Processing · Electrical Eng. & Systems 2025-02-06 Simon Arberet , Florin C. Ghesu , Riqiang Gao , Martin Kraus , Jonathan Sackett , Esa Kuusela , Ali Kamen

Accurate fluence map prediction is essential in intensity-modulated radiation therapy (IMRT) to maximize tumor coverage while minimizing dose to healthy tissues. Conventional optimization is time-consuming and dependent on planner…

Image and Video Processing · Electrical Eng. & Systems 2025-11-13 Ujunwa Mgboh , Rafi Sultan , Dongxiao Zhu , Joshua Kim

In contemporary radiotherapy planning (RTP), a key module leaf sequencing is predominantly addressed by optimization-based approaches. In this paper, we propose a novel deep reinforcement learning (DRL) model termed as Reinforced Leaf…

Machine Learning · Computer Science 2024-06-05 Riqiang Gao , Florin C. Ghesu , Simon Arberet , Shahab Basiri , Esa Kuusela , Martin Kraus , Dorin Comaniciu , Ali Kamen

In intensity-modulated radiation therapy, optimal intensity distributions of incoming beams are decomposed into linear combinations of leaf openings of a multileaf collimator (segments). In order to avoid inefficient dose delivery, the…

Medical Physics · Physics 2010-09-29 Antje Kiesel , Tobias Gauer

Purpose: To improve the delivery efficiency of VMAT by extending the recently published VMAT treatment planning algorithm vmerge to automatically generate optimal partial-arc plans. Methods and materials: A high-quality initial plan is…

Medical Physics · Physics 2015-06-05 Jeremiah Wala , Ehsan Salari , Wei Chen , David Craft

The main approach to smooth Pareto surface navigation for radiation therapy multi-criteria treatment planning involves taking real-time averages of pre-computed treatment plans. In fluence-based treatment planning, fluence maps themselves…

Medical Physics · Physics 2014-02-03 David Craft , David Papp , Jan Unkelbach

A new delivery option for cancer centers equipped with linear accelerators fitted with multi-leaf collimators (MLC) -- i.e. centers which can perform intensity modulated radiation therapy (IMRT) -- is rotational delivery. In rotational…

Medical Physics · Physics 2009-10-27 David Craft , Thomas Bortfeld

In the treatment plan optimization for intensity modulated radiation therapy (IMRT), dose-deposition coefficient (DDC) matrix is often pre-computed to parameterize the dose contribution to each voxel in the volume of interest from each…

Medical Physics · Physics 2013-03-15 Zhen Tian , Masoud Zarepisheh , Xun Jia , Steve B. Jiang

Traditional VMAT optimization often ignores dynamic machine limits, treating delivery time as an emergent property rather than a steerable parameter. This work introduces Dynamic Modulated Arc Therapy (DMAT), an intent-driven framework that…

Purpose: To develop a novel aperture-based algorithm for volumetric modulated arc therapy (VMAT) treatment plan optimization with high quality and high efficiency. Methods: The VMAT optimization problem is formulated as a large-scale convex…

Medical Physics · Physics 2015-05-19 Chunhua Men , H. Edwin Romeijn , Xun Jia , Steve B. Jiang

To analyze nonlinear dynamic systems, we developed a new technique based on the square matrix method. We propose this technique called the \convergence map" for generating particle stability diagrams similar to the frequency maps widely…

Accelerator Physics · Physics 2023-06-07 Li Hua Yu , Yoshiteru Hidaka , Victor Smaluk

Purpose: To make the planning of volumetric modulated arc therapy (VMAT) faster and to explore the tradeoffs between planning objectives and delivery efficiency. Methods: A convex multicriteria dose optimization problem is solved for an…

Medical Physics · Physics 2015-05-28 David Craft , Dualta McQuaid , Jeremiah Wala , Wei Chen , Ehsan Salari , Thomas Bortfeld

Volumetric modulated arc therapy planning is a challenging problem in high-dimensional, non-convex optimization. Traditionally, heuristics such as fluence-map-optimization-informed segment initialization use locally optimal solutions to…

Machine Learning · Computer Science 2021-11-17 Noah Bice , Mohamad Fakhreddine , Ruiqi Li , Dan Nguyen , Christopher Kabat , Pamela Myers , Niko Papanikolaou , Neil Kirby

This work addresses the radio resource management (RRM) design in downlink full-duplex integrated sensing and communications (ISAC) systems, jointly optimizing timeslot allocation and beam selection under imperfect self-interference…

Signal Processing · Electrical Eng. & Systems 2025-10-23 Luis F. Abanto-Leon , Setareh Maghsudi
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