Related papers: Disease Knowledge Transfer across Neurodegenerativ…
Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual…
Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…
We present DLTK, a toolkit providing baseline implementations for efficient experimentation with deep learning methods on biomedical images. It builds on top of TensorFlow and its high modularity and easy-to-use examples allow for a…
Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…
Cases of diabetes and related diabetic retinopathy (DR) have been increasing at an alarming rate in modern times. Early detection of DR is an important problem since it may cause permanent blindness in the late stages. In the last two…
Diabetic Retinopathy (DR), a prevalent complication in diabetes patients, can lead to vision impairment due to lesions formed on the retina. Detecting DR at an advanced stage often results in irreversible blindness. The traditional process…
Fluorodeoxyglucose positron emission tomography (FDG-PET) imaging based 3D topographic brain glucose metabolism patterns from normal controls (NC) and individuals with dementia of Alzheimer's type (DAT) are used to train a novel multi-scale…
Modelling the progression of Degenerative Diseases (DD) is essential for detection, prevention, and treatment, yet it remains challenging due to the heterogeneity in disease trajectories among individuals. Factors such as demographics,…
The current state-of-the-art deep neural networks (DNNs) for Alzheimer's Disease diagnosis use different biomarker combinations to classify patients, but do not allow extracting knowledge about the interactions of biomarkers. However, to…
Alzheimer's Disease (AD) is the most common form of dementia and often difficult to diagnose due to the multifactorial etiology of dementia. Recent works on neuroimaging-based computer-aided diagnosis with deep neural networks (DNNs) showed…
Recently, graph theory has become a popular method for characterizing brain functional organization. One important goal in graph theoretical analysis of brain networks is to identify network differences across disease types or conditions.…
Alzheimer's disease (AD), characterized by progressive cognitive decline and memory loss, presents a formidable global health challenge, underscoring the critical importance of early and precise diagnosis for timely interventions and…
The integration of Artificial Intelligence (AI) and the Internet of Medical Things (IoMT) in healthcare, through Machine Learning (ML) and Deep Learning (DL) techniques, has advanced the prediction and diagnosis of chronic diseases.…
Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…
Under the framework of network-based neurodegeneration, brain functional connectome (FC)-based Graph Neural Networks (GNN) have emerged as a valuable tool for the diagnosis and prognosis of neurodegenerative diseases such as Alzheimer's…
Dementia poses a growing challenge in our aging society. Frontotemporal dementia (FTD) and Alzheimer disease (AD) are the leading causes of early-onset dementia. FTD and AD display unique traits in their onset, progression, and treatment…
Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…
The integration of event cameras and spiking neural networks holds great promise for energy-efficient visual processing. However, the limited availability of event data and the sparse nature of DVS outputs pose challenges for effective…
Multimodal learning that integrates genomics and histopathology has shown strong potential in cancer diagnosis, yet its clinical translation is hindered by the limited availability of paired histology-genomics data. Knowledge distillation…
Retinal optical coherence tomography (OCT) images are the biomarkers for neurodegenerative diseases, which are rising in prevalence. Early detection of Alzheimer's disease using retinal OCT is a primary challenging task. This work utilizes…