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Related papers: Disease Knowledge Transfer across Neurodegenerativ…

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Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual…

Machine Learning · Statistics 2016-06-30 Peter Schulam , Raman Arora

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

Machine Learning · Computer Science 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

We present DLTK, a toolkit providing baseline implementations for efficient experimentation with deep learning methods on biomedical images. It builds on top of TensorFlow and its high modularity and easy-to-use examples allow for a…

Computer Vision and Pattern Recognition · Computer Science 2017-11-21 Nick Pawlowski , Sofia Ira Ktena , Matthew C. H. Lee , Bernhard Kainz , Daniel Rueckert , Ben Glocker , Martin Rajchl

Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Huy Hoang Nguyen , Matthew B. Blaschko , Simo Saarakkala , Aleksei Tiulpin

Cases of diabetes and related diabetic retinopathy (DR) have been increasing at an alarming rate in modern times. Early detection of DR is an important problem since it may cause permanent blindness in the late stages. In the last two…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Burcu Oltu , Büşra Kübra Karaca , Hamit Erdem , Atilla Özgür

Diabetic Retinopathy (DR), a prevalent complication in diabetes patients, can lead to vision impairment due to lesions formed on the retina. Detecting DR at an advanced stage often results in irreversible blindness. The traditional process…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Ankush Jain , Rinav Gupta , Jai Singhal

Fluorodeoxyglucose positron emission tomography (FDG-PET) imaging based 3D topographic brain glucose metabolism patterns from normal controls (NC) and individuals with dementia of Alzheimer's type (DAT) are used to train a novel multi-scale…

Modelling the progression of Degenerative Diseases (DD) is essential for detection, prevention, and treatment, yet it remains challenging due to the heterogeneity in disease trajectories among individuals. Factors such as demographics,…

Optimization and Control · Mathematics 2024-12-19 Alessandro Viani , Boris A Gutman , Emile d'Angremont , Marco Lorenzi

The current state-of-the-art deep neural networks (DNNs) for Alzheimer's Disease diagnosis use different biomarker combinations to classify patients, but do not allow extracting knowledge about the interactions of biomarkers. However, to…

Machine Learning · Computer Science 2021-09-28 Raphael Ronge , Kwangsik Nho , Christian Wachinger , Sebastian Pölsterl

Alzheimer's Disease (AD) is the most common form of dementia and often difficult to diagnose due to the multifactorial etiology of dementia. Recent works on neuroimaging-based computer-aided diagnosis with deep neural networks (DNNs) showed…

Image and Video Processing · Electrical Eng. & Systems 2022-07-06 Marla Narazani , Ignacio Sarasua , Sebastian Pölsterl , Aldana Lizarraga , Igor Yakushev , Christian Wachinger

Recently, graph theory has become a popular method for characterizing brain functional organization. One important goal in graph theoretical analysis of brain networks is to identify network differences across disease types or conditions.…

Applications · Statistics 2018-10-01 Ixavier A Higgins , Ying Guo , Suprateek Kundu , Ki Sueng Choi , Helen Mayberg

Alzheimer's disease (AD), characterized by progressive cognitive decline and memory loss, presents a formidable global health challenge, underscoring the critical importance of early and precise diagnosis for timely interventions and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Arindam Majee , Avisek Gupta , Sourav Raha , Swagatam Das

The integration of Artificial Intelligence (AI) and the Internet of Medical Things (IoMT) in healthcare, through Machine Learning (ML) and Deep Learning (DL) techniques, has advanced the prediction and diagnosis of chronic diseases.…

Machine Learning · Computer Science 2024-10-02 Akeem Temitope Otapo , Alice Othmani , Ghazaleh Khodabandelou , Zuheng Ming

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Under the framework of network-based neurodegeneration, brain functional connectome (FC)-based Graph Neural Networks (GNN) have emerged as a valuable tool for the diagnosis and prognosis of neurodegenerative diseases such as Alzheimer's…

Neurons and Cognition · Quantitative Biology 2023-07-14 Zijian Dong , Yilei Wu , Yu Xiao , Joanna Su Xian Chong , Yueming Jin , Juan Helen Zhou

Dementia poses a growing challenge in our aging society. Frontotemporal dementia (FTD) and Alzheimer disease (AD) are the leading causes of early-onset dementia. FTD and AD display unique traits in their onset, progression, and treatment…

Signal Processing · Electrical Eng. & Systems 2024-09-26 Shivani Ranjan , Lalan Kumar

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

The integration of event cameras and spiking neural networks holds great promise for energy-efficient visual processing. However, the limited availability of event data and the sparse nature of DVS outputs pose challenges for effective…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Yuqi Xie , Shuhan Ye , Yi Yu , Chong Wang , Qixin Zhang , Jiazhen Xu , Le Shen , Yuanbin Qian , Jiangbo Qian , Guoqi Li

Multimodal learning that integrates genomics and histopathology has shown strong potential in cancer diagnosis, yet its clinical translation is hindered by the limited availability of paired histology-genomics data. Knowledge distillation…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Yongxin Guo , Hao Lu , Onur C. Koyun , Zhengjie Zhu , Muhammet Fatih Demir , Metin Nafi Gurcan

Retinal optical coherence tomography (OCT) images are the biomarkers for neurodegenerative diseases, which are rising in prevalence. Early detection of Alzheimer's disease using retinal OCT is a primary challenging task. This work utilizes…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Siva Manohar Reddy Kesu , Neelam Sinha , Hariharan Ramasangu , Thomas Gregor Issac