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Many cell functions are accomplished thanks to intracellular transport mechanisms of macromolecules along filaments. Molecular motors such as dynein or kinesin are proteins playing a primary role in these processes. The behavior of such…

Chaotic Dynamics · Physics 2010-12-21 Donatello Materassi , Subhrajit Roychowdhury , Murti V. Salapaka

We study the dynamics and phase behaviour of a dry suspension of microtubules and molecular motors. We obtain a set of continuum equations by rigorously coarse graining a microscopic model where motor-induced interactions lead to parallel…

Soft Condensed Matter · Physics 2018-06-27 Ivan Maryshev , Andrew B. Goryachev , Davide Marenduzzo , Alexander Morozov

Human motion capture is frequently used to study rehabilitation and clinical problems, as well as to provide realistic animation for the entertainment industry. IMU-based systems, as well as Marker-based motion tracking systems, are the…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Omid Taheri , Hassan Salarieh , Aria Alasty

We here present a model of nonlinear dynamics of microtubules (MT) in the context of modified extended tanh-function (METHF) method. We rely on the ferroelectric model of MTs published earlier by Satari\'c et al [1] where the motion of MT…

Tracking many cells in time-lapse 3D image sequences is an important challenging task of bioimage informatics. Motivated by a study of brain-wide 4D imaging of neural activity in C. elegans, we present a new method of multi-cell tracking.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-18 Osamu Hirose , Shotaro Kawaguchi , Terumasa Tokunaga , Yu Toyoshima , Takayuki Teramoto , Sayuri Kuge , Takeshi Ishihara , Yuichi Iino , Ryo Yoshida

The goal of multi-object tracking is to detect and track all objects in a scene while maintaining unique identifiers for each, by associating their bounding boxes across video frames. This association relies on matching motion and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Momir Adžemović , Predrag Tadić , Andrija Petrović , Mladen Nikolić

Along a microtubule, certain active motors propel themselves in one direction whereas others propel themselves in the opposite direction. For example, the cargo transporting motor proteins dynein and kinesin propel themselves towards the…

Soft Condensed Matter · Physics 2016-04-01 Anton Souslov , Paul M. Goldbart

Movements of molecular motors on cytoskeletal filaments are described by directed walks on a line. Detachment from this line is allowed to occur with a small probability. Motion in the surrounding fluid is described by symmetric random…

Statistical Mechanics · Physics 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

Microtubules (MTs) represent basic components of a cytoskeleton. The present work studies nonlinear dynamics of MTs assuming tangential oscillations of the dimers. We introduce a two component model and show that the dynamics of MTs can be…

Biological Physics · Physics 2023-02-06 Slobodan Zdravković , Slobodan Zeković

We use Stokesian Dynamics simulations to study the microscopic motion of particles suspended in fluids passing through porous media. We construct model porous media with fixed spherical particles, and allow mobile ones to move through this…

Disordered Systems and Neural Networks · Physics 2009-10-31 Jysoo Lee , Joel Koplik

In this work we study the assisted translocation of a polymer across a membrane nanopore, inside which a molecular motor exerts a force fuelled by the hydrolysis of ATP molecules. In our model the motor switches to its active state for a…

Soft Condensed Matter · Physics 2018-03-26 A. Fiasconaro , J. J. Mazo , F. Falo

Many cellular processes are tightly connected to the dynamics of microtubules (MTs). While in neuronal axons MTs mainly regulate intracellular trafficking, they participate in cytoskeleton reorganization in many other eukaryotic cells,…

Subcellular Processes · Quantitative Biology 2017-12-19 M. Reza Shaebani , Aravind Pasula , Albrecht Ott , Ludger Santen

We use optical trapping to continuously bend an isolated microtubule while simultaneously measuring the applied force and the resulting filament strain, thus allowing us to determine its elastic properties over a wide range of applied…

Biological Physics · Physics 2018-07-24 Edvin Memet , Feodor Hilitski , Margaret A Morris , Walter J Schwenger , Zvonimir Dogic , L Mahadevan

We investigate the dynamics of an active gel of bundled microtubules that is driven by clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of thousands of molecular motors drives the gel to a highly…

Soft Condensed Matter · Physics 2015-06-23 Gil Henkin , Stephen J. DeCamp , Daniel TN Chen , Tim Sanchez , Zvonimir Dogic

We develop a theoretical and computational approach to deal with systems that involve a disparate range of spatio-temporal scales, such as those comprised of colloidal particles or polymers moving in a fluidic molecular environment. Our…

Soft Condensed Matter · Physics 2017-10-27 Adwait V. Datar , Maria Fyta , Umberto Marini Bettolo Marconi , Simone Melchionna

Comprehensive understanding of particle motion in microfluidic devices is essential to unlock novel technologies for shape-based separation and sorting of microparticles like microplastics, cells and crystal polymorphs. Such particles…

This paper provides the phase transition analysis of a reaction diffusion equations system modeling dynamic instability of microtubules. For this purpose we have generalized the macroscopic model studied by Mour\~ao et all [MSS]. This model…

Analysis of PDEs · Mathematics 2015-06-17 Shantia Yarahmadian , Masoud Yari

We propose cotunneling as the microscopic mechanism that makes possible inelastic electron spectroscopy of magnetic atoms in surfaces for a wide range of systems, including single magnetic adatoms, molecules and molecular stacks. We…

Mesoscale and Nanoscale Physics · Physics 2011-08-26 F. Delgado , J. Fernández-Rossier

Kalman filters constitute a scalable and robust methodology for approximate Bayesian inference, matching first and second order moments of the target posterior. To improve the accuracy in nonlinear and non-Gaussian settings, we extend this…

Statistics Theory · Mathematics 2024-09-04 L. Wang , N. Nüsken

Intracellular transport along microtubules or actin filaments, powered by molecular motors such as kinesins, dyneins or myosins, has been recently modeled using one-dimensional driven lattice gases. We discuss some generalizations of these…

Biological Physics · Physics 2007-10-09 Paolo Pierobon
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