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In some real world applications, such as spectrometry, functional models achieve better predictive performances if they work on the derivatives of order m of their inputs rather than on the original functions. As a consequence, the use of…

Statistics Theory · Mathematics 2011-05-04 Fabrice Rossi , Nathalie Villa-Vialaneix

Motivated by renal imaging studies that combine renogram curves with pharmacokinetic and demographic covariates, we propose Hybrid partial least squares (Hybrid PLS) for simultaneous supervised dimension reduction and regression in the…

Methodology · Statistics 2026-01-26 Jongmin Mun , Jeong Hoon Jang

The multivariate regression interpretation of the Gaussian chain graph model simultaneously parametrizes (i) the direct effects of $p$ predictors on $q$ outcomes and (ii) the residual partial covariances between pairs of outcomes. We…

Methodology · Statistics 2024-03-28 Yunyi Shen , Claudia Solís-Lemus , Sameer K. Deshpande

Tabular regression is a well-studied problem with numerous industrial applications, yet most existing approaches focus on point estimation, often leading to overconfident predictions. This issue is particularly critical in industrial…

1. Hidden Markov models (HMMs) are powerful tools for modelling time-series data with underlying state structure. However, selecting appropriate parametric forms for the state-dependent distributions is often challenging and can lead to…

Symbolic regression (SR) is a powerful technique for discovering the analytical mathematical expression from data, finding various applications in natural sciences due to its good interpretability of results. However, existing methods face…

Machine Learning · Computer Science 2024-07-11 Xieting Chu , Hongjue Zhao , Enze Xu , Hairong Qi , Minghan Chen , Huajie Shao

The quantitative structure-activity relationship (QSAR) regression model is a commonly used technique for predicting biological activities of compounds using their molecular descriptors. Predictions from QSAR models can help, for example,…

Biomolecules · Quantitative Biology 2023-04-04 Yuting Xu , Andy Liaw , Robert P. Sheridan , Vladimir Svetnik

Fitting statistical models to spatiotemporal data requires finding the right balance between imposing smoothness and following the data. In the context of p-splines, we propose a Bayesian framework for choosing the smoothing parameter which…

Applications · Statistics 2013-10-30 A. W. Bowman , L. Evers , D. Molinari , W. R. Jones , M. J. Spence

It is commonly recognized that color variations caused by differences in stains is a critical issue for histopathology image analysis. Existing methods adopt color matching, stain separation, stain transfer or the combination of them to…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Hai-Li Ye , Da-Han Wang

The graph structure of a Bayesian network (BN) can be learned from data using the well-known score-and-search approach. Previous work has shown that incorporating structured representations of the conditional probability distributions…

Machine Learning · Computer Science 2022-06-22 Charupriya Sharma , Peter van Beek

One way to interject knowledge into clinically impactful forecasting is to use data assimilation, a nonlinear regression that projects data onto a mechanistic physiologic model, instead of a set of functions, such as neural networks. Such…

Quantitative Methods · Quantitative Biology 2019-02-07 DJ Albers , M Levine , L Mamykina , G Hripcsak

Given a data set (t_i, y_i), i=1,..., n with the t_i in [0,1] non-parametric regression is concerned with the problem of specifying a suitable function f_n:[0,1] -> R such that the data can be reasonably approximated by the points (t_i,…

Methodology · Statistics 2009-03-18 P. L. Davies , M. Meise

It is often desirable to build a statistical emulator of a complex computer simulator in order to perform analysis which would otherwise be computationally infeasible. We propose methodology to model multivariate output from a computer…

Methodology · Statistics 2017-01-03 Veronica E. Bowman , David C. Woods

We present a local and transferable machine learning approach capable of predicting the real-space density response of both molecules and periodic systems to external homogeneous electric fields. The new method, SALTER, builds on the…

Chemical Physics · Physics 2023-07-19 Alan M Lewis , Paolo Lazzaroni , Mariana Rossi

Identifying which observables most effectively constrain model parameters can be computationally prohibitive when considering full likelihoods of many correlated observables. This is especially important for, e.g., hadronization models,…

High Energy Physics - Phenomenology · Physics 2026-02-03 Benoît Assi , Christian Bierlich , Rikab Gambhir , Phil Ilten , Tony Menzo , Stephen Mrenna , Manuel Szewc , Michael K. Wilkinson , Jure Zupan

Sparse linear regression methods for high-dimensional data commonly assume that residuals have constant variance, which can be violated in practice. For example, Aphasia Quotient (AQ) is a critical measure of language impairment and informs…

Methodology · Statistics 2024-07-16 Anja Zgodic , Ray Bai , Jiajia Zhang , Yuan Wang , Chris Rorden , Alexander McLain

Methods for choosing a fixed set of knot locations in additive spline models are fairly well established in the statistical literature. While most of these methods are in principle directly extendable to non-additive surface models, they…

Computation · Statistics 2018-07-03 Feng Li , Mattias Villani

This paper presents a new methodology, called AFSSEN, to simultaneously select significant predictors and produce smooth estimates in a high-dimensional function-on-scalar linear model with a sub-Gaussian errors. Outcomes are assumed to lie…

Methodology · Statistics 2019-05-27 Ardalan Mirshani , Matthew Reimherr

We consider estimation of a functional of the data distribution based on i.i.d. observations. We assume the target function can be defined as the minimizer of the expectation of a loss function over a class of $d$-variate real valued cadlag…

Statistics Theory · Mathematics 2023-02-01 Mark van der Laan

For the past two decades, single-index model, a special case of projection pursuit regression, has proven to be an efficient way of coping with the high dimensional problem in nonparametric regression. In this paper, based on weakly…

Statistics Theory · Mathematics 2007-05-23 Li Wang , Lijian Yang