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Measuring and quantifying non-equilibrium dynamics in active biological systems is a major challenge, because of their intrinsic stochastic nature and the limited number of variables accessible in any real experiment. We investigate what…

Biological Physics · Physics 2018-07-25 Federica Mura , Grzegorz Gradziuk , Chase P. Broedersz

Biological assemblies such as chromosomes, membranes, and the cytoskeleton are driven out of equilibrium at the nanoscale by enzymatic activity and molecular motors. Similar non-equilibrium dynamics can be realized in synthetic systems,…

Biological Physics · Physics 2020-06-04 Federica Mura , Grzegorz Gradziuk , Chase P. Broedersz

Marginally stable systems exhibit rich critical mechanical behavior. Such isostatic assemblies can be driven out of equilibrium by internal activity, but it remains unclear how the isostatic and critical nature of such systems affects their…

Soft Condensed Matter · Physics 2019-07-17 Federico S. Gnesotto , Benedikt M. Remlein , Chase P. Broedersz

Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce broken detailed balance at the molecular scale. This molecular scale breaking of detailed balance is crucial to achieve biological functions such as…

Biological Physics · Physics 2018-05-02 F. Gnesotto , F. Mura , J. Gladrow , C. P. Broedersz

Living cells exhibit an important out-of-equilibrium mechanical activity, mainly due to the forces generated by molecular motors. These motor proteins, acting individually or collectively on the cytoskeleton, contribute to the violation of…

Biological Physics · Physics 2009-01-21 Francois Gallet , Delphine Arcizet , Pierre Bohec , Alain Richert

It has been supposed that the interplay of elasticity and activity plays a key role in triggering the non-equilibrium behaviors in biological systems. However, the experimental model system is missing to investigate the spatiotemporally…

Soft Condensed Matter · Physics 2024-07-31 Tian-liang Xu , Chao-ran Qin , Bin Tang , Jin-cheng Gao , Jiankang Zhou , Kang Chen , Tian Hui Zhang , Wen-de Tian

We propose a model for the dynamics of a probe embedded in a living cell, where both thermal fluctuations and nonequilibrium activity coexist. The model is based on a confining harmonic potential describing the elastic cytoskeletal matrix,…

Biological Physics · Physics 2015-06-18 É. Fodor , M. Guo , N. S. Gov , P. Visco , D. A. Weitz , F. van Wijland

Time-lapse microscopy imaging provides direct access to the dynamics of soft and living systems. At mesoscopic scales, such microscopy experiments reveal intrinsic fluctuations, which may have both thermal and non-equilibrium origins. These…

Biological Physics · Physics 2020-12-02 F. S. Gnesotto , G. Gradziuk , P. Ronceray , C. P. Broedersz

Non-equilibrium dynamics are present in many aspects of our lives, ranging from microscopic physical systems to the functioning of the brain. What characterizes stochastic models of non-equilibrium processes is the breaking of the…

Statistical Mechanics · Physics 2025-01-27 Sergei Shmakov , Peter B. Littlewood

The interplay between activity and elasticity often found in active and living systems triggers a plethora of autonomous behaviors ranging from self-assembly and collective motion to actuation. Amongst these, spontaneous self-oscillations…

Soft Condensed Matter · Physics 2023-04-07 Ellen Zheng , Martin Brandenbourger , Louis Robinet , Peter Schall , Edan Lerner , Corentin Coulais

Equilibrium statistical mechanics provides a robust framework for characterizing phase transitions in systems whose microsopic dynamics are time-reversible. Efforts to develop and validate theoretical frameworks for time-irreversible,…

Soft Condensed Matter · Physics 2025-12-18 Stuart J. Thomson , Jack-William Barotta , Daniel M. Harris

Scale invariance is a central organizing principle in physics, underlying phenomena that range from critical behaviour in statistical mechanics to transport and chaos in nonlinear dynamical systems. Here we present a unified and physically…

Statistical Mechanics · Physics 2026-02-23 Edson D. Leonel , Diego F. M. Oliveira

Time-reversal symmetry breaking and entropy production are universal features of nonequilibrium phenomena. Despite its importance in the physics of active and living systems, the entropy production of systems with many degrees of freedom…

We experimentally and theoretically investigate the non-equilibrium phase structure of a well-controlled driven-disspative quantum spin system governed by the interplay of coherent driving, spontaneous decay and long-range spin-spin…

Atomic Physics · Physics 2018-08-15 S. Helmrich , A. Arias , S. Whitlock

Biological machines like molecular motors and enzymes operate in dynamic cycles representable as stochastic flows on networks. Current stochastic dynamics describes such flows on fixed networks. Here, we develop a scalable approach to…

Statistical Mechanics · Physics 2026-03-02 Ying-Jen Yang , Ken A. Dill

In the present paper which is a sequel to [N.B. Volkov and A.M. Iskoldsky The dynamics of vortex structures and states of current: 1;[1]], the dynamics of non-equilibrium phase transitions and states of current in electrophysical systems…

chao-dyn · Physics 2008-02-03 N. B. Volkov , A. M. Iskoldsky

In this work we develop a general formalism that categorizes the action of broken scale invariance on the non-equilibrium dynamics of non-relativistic quantum systems. This approach is equally applicable to both strongly and weakly…

Quantum Gases · Physics 2018-07-11 Jeff Maki , Li-Ming Zhao , Fei Zhou

For the hopping dynamics in a one-dimensional model, containing energy and barrier disorder, we determine the linear and nonlinear response to an external field for arbitrary external frequencies. The calculation is performed in analytical…

Disordered Systems and Neural Networks · Physics 2013-02-15 Clara Mattner , Bernhard Roling , Andreas Heuer

In nonlinear systems, small perturbations are conventionally attributed to negligible nonlinearity, justifying linear approximations. Here, we uncover a notable exception to this paradigm in an electrokinetic (EK) flow. Using a novel dual…

Fluid Dynamics · Physics 2026-04-16 Jin'an Pang , Guangyin Jing , Xiaoqiang Feng , Kaige Wang , Wei Zhao

The rate of metastable decay in nonequilibrium systems is expected to display scaling behavior: i.e., the logarithm of the decay rate should scale as a power of the distance to a bifurcation point where the metastable state disappears.…

Statistical Mechanics · Physics 2009-09-29 Oleg Kogan
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