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Objective: Anemia is a frequent comorbidity in hemodialysis patients that can be successfully treated by administering erythropoiesis-stimulating agents (ESAs). ESAs dosing is currently based on clinical protocols that often do not account…
We utilize dynamical modes as features derived from Continuous Glucose Monitoring (CGM) data to detect meal events. By leveraging the inherent properties of underlying dynamics, these modes capture key aspects of glucose variability,…
Traditional models of glucose-insulin dynamics rely on heuristic parameterizations chosen to fit observations within a laboratory setting. However, these models cannot describe glucose dynamics in daily life. One source of failure is in…
Diabetes, especially T2DM, continues to be a significant health problem. One of the major concerns associated with diabetes is the development of its complications. Diabetic nephropathy, one of the chronic complication of diabetes,…
Postprandial hyperglycemia, marked by the blood glucose level exceeding the normal range after consuming a meal, is a critical indicator of progression toward type 2 diabetes in people with prediabetes and in healthy individuals. A key…
This study develops a cloud-based deep learning system for early prediction of diabetes, leveraging the distributed computing capabilities of the AWS cloud platform and deep learning technologies to achieve efficient and accurate risk…
The role played by physical activity in slowing down the progression of type-2 diabetes is well recognized. However, except for general clinical guidelines, quantitative real-time estimates of the recommended amount of physical activity,…
Structure-based drug design (SBDD) aims to discover drug candidates by finding molecules (ligands) that bind tightly to a disease-related protein (targets), which is the primary approach to computer-aided drug discovery. Recently, applying…
Modeling the dynamics of probability distributions from time-dependent data samples is a fundamental problem in many fields, including digital health. The goal is to analyze how the distribution of a biomarker, such as glucose, changes over…
Diabetes is a chronic metabolic disease characterized by elevated blood glucose levels, leading to complications like heart disease, kidney failure, and nerve damage. Accurate state-level predictions are vital for effective healthcare…
In the context of time-series forecasting, we propose a LSTM-based recurrent neural network architecture and loss function that enhance the stability of the predictions. In particular, the loss function penalizes the model, not only on the…
Diabetes is an epidemic disease of the 21st century and is growing globally. Although, final diabetes treatments and cure are still on research phase, related complications of diabetes endanger life of diabetic patients. Diabetic coma which…
Quantum algorithms are prominent in the pursuit of achieving quantum advantage in various computational tasks. However, addressing challenges, such as limited qubit coherence and high error rate in near-term devices, requires extensive…
During the entire training process of the ASR model, the intensity of data augmentation and the approach of calculating training loss are applied in a regulated manner based on preset parameters. For example, SpecAugment employs a…
Non-invasive glucose monitoring remains a critical challenge in the management of diabetes. HRV during sleep shows promise for glucose prediction however, age-related autonomic changes significantly confound traditional HRV analyses. We…
Modern treatments for Type 1 diabetes (T1D) use devices known as artificial pancreata (APs), which combine an insulin pump with a continuous glucose monitor (CGM) operating in a closed-loop manner to control blood glucose levels. In…
Diabetes, a pervasive and enduring health challenge, imposes significant global implications on health, financial healthcare systems, and societal well-being. This study undertakes a comprehensive exploration of various structural learning…
Recent advances in SSL enabled novel medical AI models, known as foundation models, offer great potential for better characterizing health from diverse biomedical data. CGM provides rich, temporal data on glycemic patterns, but its full…
Adaptive bitrate (ABR) algorithms are used to adapt the video bitrate based on the network conditions to improve the overall video quality of experience (QoE). Recently, reinforcement learning (RL) and asynchronous advantage actor-critic…
In the Oral Glucose Tolerance Test (OGTT), a patient, after an overnight fast ingests a load of glucose. Then measurements of glucose concentration are taken every 30 minutes during two hours. The test is used to aid diagnosis of diabetes,…