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One of the roadmap plans for quantum computers is an integration within HPC ecosystems assigning them a role of accelerators for a variety of computationally hard tasks. However, in the near term, quantum hardware will be in a constant…

Quantum Physics · Physics 2018-10-19 Ruslan Shaydulin , Hayato Ushijima-Mwesigwa , Ilya Safro , Susan Mniszewski , Yuri Alexeev

Optical data center networks (DCNs) are emerging as a promising design for cloud infrastructure. However, existing optical DCN architectures operate as closed ecosystems, tying software solutions to specific optical hardware. We introduce…

Networking and Internet Architecture · Computer Science 2025-08-07 Yiming Lei , Federico De Marchi , Jialong Li , Raj Joshi , Balakrishnan Chandrasekaran , Yiting Xia

Quantum computers promise polynomial or exponential speed-up in solving certain problems compared to classical computers. However, in practical use, there are currently a number of fundamental technical challenges. One of them concerns the…

Emerging Technologies · Computer Science 2024-03-20 Markus Zajac , Uta Störl

The rapid advancements in quantum computing necessitate a scientific and rigorous approach to the construction of a corresponding software ecosystem, a topic underexplored and primed for systematic investigation. This chapter takes an…

The increasing energy demands and carbon footprint of large-scale AI require intelligent workload management in globally distributed data centers. Yet progress is limited by the absence of benchmarks that realistically capture the interplay…

Quantum processing unit (QPU) has to satisfy highly demanding quantity and quality requirements on its qubits to produce accurate results for problems at useful scales. Furthermore, classical simulations of quantum circuits generally do not…

Emerging Technologies · Computer Science 2022-07-05 Wei Tang , Margaret Martonosi

A new method that accurately describes strongly correlated states and captures dynamical correlation is presented. It is derived as a modification of coupled-cluster theory with single and double excitations (CCSD) through consideration of…

Chemical Physics · Physics 2013-07-15 Daniel Kats , Frederick R. Manby

The quest for real-time dynamic optimization solutions in the process industry represents a formidable computational challenge, particularly within the realm of applications like model-predictive control, where rapid and reliable…

Optimization and Control · Mathematics 2024-04-29 Dennis Michael Nenno , Adrian Caspari

As quantum computers scale, single-chip architectures face inherent limitations in qubit count. It drives the need for modular quantum computing and Quantum Data Centers (QDCs), where multiple quantum processor units (QPUs) are…

Quantum Physics · Physics 2026-05-15 Seyed Navid Elyasi , Paolo Monti , Jun Li , Rui Lin

Practical Quantum Machine Learning (QML) is challenged by noise, limited scalability, and poor trainability in Variational Quantum Circuits (VQCs) on current hardware. We propose a multi-chip ensemble VQC framework that systematically…

Machine Learning · Computer Science 2025-05-21 Junghoon Justin Park , Jiook Cha , Samuel Yen-Chi Chen , Huan-Hsin Tseng , Shinjae Yoo

With the potential of quantum algorithms to solve intractable classical problems, quantum computing is rapidly evolving and more algorithms are being developed and optimized. Expressing these quantum algorithms using a high-level language…

Quantum Physics · Physics 2020-05-28 N. Khammassi , I. Ashraf , J. v. Someren , R. Nane , A. M. Krol , M. A. Rol , L. Lao , K. Bertels , C. G. Almudever

Graph clustering and community detection are central problems in modern data mining. The increasing need for analyzing billion-scale data calls for faster and more scalable algorithms for these problems. There are certain trade-offs between…

Social and Information Networks · Computer Science 2021-08-05 Jessica Shi , Laxman Dhulipala , David Eisenstat , Jakub Łącki , Vahab Mirrokni

The purpose of this paper is to explore the applications of quantum computing to energy systems optimization problems and discuss some of the challenges faced by quantum computers with techniques to overcome them. The basic concepts…

Quantum Physics · Physics 2020-03-03 Akshay Ajagekar , Fengqi You

We present an algorithm for quantum-assisted cluster analysis (QACA) that makes use of the topological properties of a D-Wave 2000Q quantum processing unit (QPU). Clustering is a form of unsupervised machine learning, where instances are…

Quantum Physics · Physics 2018-03-09 Florian Neukart , David Von Dollen , Christian Seidel

The computing ecosystem has always had deep impacts on society and technology and profoundly changed our lives in myriads of ways. Despite decades of impressive Moore's Law performance scaling and other growth in the computing ecosystem…

Emerging Technologies · Computer Science 2019-03-27 Margaret Martonosi , Martin Roetteler

Molecular docking plays a pivotal role in drug discovery and precision medicine, enabling us to understand protein functions and advance novel therapeutics. Here, we introduce a potential alternative solution to this problem, the…

Quantum Physics · Physics 2024-05-17 Qi-Ming Ding , Yi-Ming Huang , Xiao Yuan

Quantum computing has demonstrated potential for solving complex optimization problems; however, its application to spatial regionalization remains underexplored. Spatial contiguity, a fundamental constraint requiring spatial entities to…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-03 Yunhan Chang , Amr Magdy , Federico M. Spedalieri

We assess the prospects for algorithms within the general framework of quantum annealing (QA) to achieve a quantum speedup relative to classical state of the art methods in combinatorial optimization and related sampling tasks. We argue for…

Quantum Physics · Physics 2021-06-22 E. J. Crosson , D. A. Lidar

Coflow provides a key application-layer abstraction for capturing communication patterns, enabling the efficient coordination of parallel data flows to reduce job completion times in distributed systems. Modern data center networks (DCNs)…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-10 Xin Wang , Hong Shen , Hui Tian , Dong Wang

The Cactus Framework is an open-source, modular, portable programming environment for the collaborative development and deployment of scientific applications using high-performance computing. Its roots reach back to 1996 at the National…

Computational Engineering, Finance, and Science · Computer Science 2013-09-17 Frank Löffler , Steven R. Brandt , Gabrielle Allen , Erik Schnetter