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Many researches have been working on the protein folding problem from more than half century. Protein folding is indeed one of the major unsolved problems in science. In this work, we discuss a model for the simulation of protein…

Optimization and Control · Mathematics 2008-11-20 A. Mucherino , O. Seref , P. M. Pardalos

Sequential learning in physical networks is hindered by catastrophic forgetting, where training a new task erases solutions to earlier ones. We show that we can significantly enhance memory of previous tasks by introducing a hard threshold…

Disordered Systems and Neural Networks · Physics 2025-12-04 Purba Chatterjee , Marcelo Guzman , Andrea J. Liu

We consider optimal distributed computation of a given function of distributed data. The input (data) nodes and the sink node that receives the function form a connected network that is described by an undirected weighted network graph. The…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-07-15 Pooja Vyavahare , Nutan Limaye , D. Manjunath

We revisit the concept of minimal rigidity as applied to soft repulsive, frictionless sphere packings in two-dimensions with the introduction of the jamming graph. Minimal rigidity is a purely combinatorial property encoded via Laman's…

Soft Condensed Matter · Physics 2015-06-16 Jorge H. Lopez , L. Cao , J. M. Schwarz

We introduce several generalizations of classical computer science problems obtained by replacing simpler objective functions with general submodular functions. The new problems include submodular load balancing, which generalizes load…

Data Structures and Algorithms · Computer Science 2010-06-02 Zoya Svitkina , Lisa Fleischer

By removing parameters from deep neural networks, unstructured pruning methods aim at cutting down memory footprint and computational cost, while maintaining prediction accuracy. In order to tackle this otherwise intractable problem, many…

Machine Learning · Computer Science 2020-06-23 César Laurent , Camille Ballas , Thomas George , Nicolas Ballas , Pascal Vincent

Classical optimization is a cornerstone of the success of variational quantum algorithms, which often require determining the derivatives of the cost function relative to variational parameters. The computation of the cost function and its…

Quantum Physics · Physics 2025-07-15 Muhammad Umer , Eleftherios Mastorakis , Dimitris G. Angelakis

The fundamental matrix can be estimated from point matches. The current gold standard is to bootstrap the eight-point algorithm and two-view projective bundle adjustment. The eight-point algorithm first computes a simple linear least…

Optimization and Control · Mathematics 2014-03-20 Florian Bugarin , Adrien Bartoli , Didier Henrion , Jean-Bernard Lasserre , Jean-José Orteu , Thierry Sentenac

Although existing medical image segmentation methods provide impressive pixel-wise accuracy, they often neglect topological correctness, making their segmentations unusable for many downstream tasks. One option is to retrain such models…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Liu Li , Hanchun Wang , Matthew Baugh , Qiang Ma , Weitong Zhang , Cheng Ouyang , Daniel Rueckert , Bernhard Kainz

Designing and implementing systems as an interconnection of smaller subsystems is a common practice for modularity and standardization of components and design algorithms. Although not typically cast in this framework, many of these…

Systems and Control · Computer Science 2016-06-29 Sefa Demirtas , Alan V. Oppenheim

Approximate unlearning has gained popularity as an approach to efficiently update an LLM so that it behaves (roughly) as if it was not trained on a subset of data to begin with. However, existing methods are brittle in practice and can…

Machine Learning · Computer Science 2025-04-08 Kevin Kuo , Amrith Setlur , Kartik Srinivas , Aditi Raghunathan , Virginia Smith

We report experimental results on the dynamics of a granular packing submitted to high-intensity focused ultrasound. Acoustic radiation pressure is shown to remotely induce local rearrangements within a pile as well as global motion around…

Soft Condensed Matter · Physics 2016-08-30 Pierre Lidon , Nicolas Taberlet , Sebastien Manneville

Recent semi-dense image matching methods have achieved remarkable success, but two long-standing issues still impair their performance. At the coarse stage, the over-exclusion issue of their mutual nearest neighbor (MNN) matching layer…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Ke Jin , Jiming Chen , Qi Ye

We show that learning can be improved by using loss functions that evolve cyclically during training to emphasize one class at a time. In underparameterized networks, such dynamical loss functions can lead to successful training for…

Machine Learning · Computer Science 2021-06-24 Miguel Ruiz-Garcia , Ge Zhang , Samuel S. Schoenholz , Andrea J. Liu

Machine unlearning is an emerging field that selectively removes specific data samples from a trained model. This capability is crucial for addressing privacy concerns, complying with data protection regulations, and correcting errors or…

Machine Learning · Computer Science 2025-01-29 Zitong Li , Qingqing Ye , Haibo Hu

A new general algorithm for optimization of potential functions for protein folding is introduced. It is based upon gradient optimization of the thermodynamic stability of native folds of a training set of proteins with known structure. The…

Condensed Matter · Physics 2009-11-10 Ole Winther , Anders Krogh

There is proposed a method for improving the convergence of Fourier series by function systems, orthogonal at the segment, the application of which allows for smooth functions to receive uniformly convergent series. There is also proposed…

Numerical Analysis · Mathematics 2018-05-18 Volodymyr Denysiuk

Structural network embedding is a crucial step in enabling effective downstream tasks for complex systems that aims to project a network into a lower-dimensional space while preserving similarities among nodes. We introduce a simple and…

Social and Information Networks · Computer Science 2024-12-23 Giuseppe Squillace , Mirco Tribastone , Max Tschaikowski , Andrea Vandin

Tensor decomposition is one of the fundamental technique for model compression of deep convolution neural networks owing to its ability to reveal the latent relations among complex structures. However, most existing methods compress the…

Computer Vision and Pattern Recognition · Computer Science 2021-12-08 Bo-Shiuan Chu , Che-Rung Lee

With the growth of model and data sizes, a broad effort has been made to design pruning techniques that reduce the resource demand of deep learning pipelines, while retaining model performance. In order to reduce both inference and training…

Machine Learning · Computer Science 2026-02-24 Dayana Savostianova , Emanuele Zangrando , Gianluca Ceruti , Francesco Tudisco
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