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Finding global optima in high-dimensional optimization problems is extremely challenging since the number of function evaluations required to sufficiently explore the search space increases exponentially with its dimensionality.…

Machine Learning · Computer Science 2022-11-04 Julian F. Schumann , Alejandro M. Aragón

The energy landscapes of proteins have evolved to be different from most random heteropolymers. Many studies have concluded that evolutionary selection for rapid and reliable folding to a given structure that is stable at biological…

Disordered Systems and Neural Networks · Physics 2009-11-10 Steven S. Plotkin , Peter G. Wolynes

To reduce model size during post-training, compression methods, including knowledge distillation, low-rank approximation, and pruning, are often applied after fine-tuning the model. However, sequential fine-tuning and compression sacrifices…

Machine Learning · Computer Science 2025-05-29 Xiangyu Chen , Jing Liu , Ye Wang , Matthew Brand , Pu , Wang , Toshiaki Koike-Akino

Scaling laws motivate the development of Time Series Foundation Models (TSFMs) that pre-train vast parameters and achieve remarkable zero-shot forecasting performance. Surprisingly, even after fine-tuning, TSFMs cannot consistently…

Machine Learning · Computer Science 2025-12-23 Lifan Zhao , Yanyan Shen , Zhaoyang Liu , Xue Wang , Jiaji Deng

Symmetric quantum signal processing provides a parameterized representation of a real polynomial, which can be translated into an efficient quantum circuit for performing a wide range of computational tasks on quantum computers. For a given…

Quantum Physics · Physics 2022-11-09 Jiasu Wang , Yulong Dong , Lin Lin

Recent studies showed that the generalization of neural networks is correlated with the sharpness of the loss landscape, and flat minima suggests a better generalization ability than sharp minima. In this paper, we propose a novel method…

Machine Learning · Computer Science 2024-05-24 Yuyan Zhou , Ye Li , Lei Feng , Sheng-Jun Huang

Finetuning a pretrained model has become a standard approach for training neural networks on novel tasks, resulting in fast convergence and improved performance. In this work, we study an alternative finetuning method, where instead of…

Machine Learning · Computer Science 2023-07-04 Gal Kaplun , Andrey Gurevich , Tal Swisa , Mazor David , Shai Shalev-Shwartz , Eran Malach

We study the critical behavior of low-frequency vibrations of packings with pinned particles near the jamming point. Soft modes form a plateau in the density of states and its frequency is controlled by the contact number as the ordinary…

Soft Condensed Matter · Physics 2025-12-08 Kumpei Shiraishi , Yusuke Hara

We consider a quasi two-dimensional network connection growth model that minimizes the wiring cost while maximizing the network connections, but at the same time edge crossings are penalized or forbidden. This model is mapped to a dilute…

Statistical Mechanics · Physics 2021-12-15 An-Liang Cheng , Pik-Yin Lai

We adapt previous research on category theory and topological unsupervised learning to develop a functorial perspective on manifold learning, also known as nonlinear dimensionality reduction. We first characterize manifold learning…

Machine Learning · Computer Science 2022-11-04 Dan Shiebler

Organisms in nature, such as Cephalopods and Pachyderms, exploit stiffness modulation to achieve amazing dexterity in the control of their appendages. In this paper, we explore the phenomenon of layer jamming, which is a popular stiffness…

Robotics · Computer Science 2026-04-22 Jessica Gumowski , Krishna Manaswi Digumarti , David Howard

Extremal Optimization, a recently introduced meta-heuristic for hard optimization problems, is analyzed on a simple model of jamming. The model is motivated first by the problem of finding lowest energy configurations for a disordered spin…

Statistical Mechanics · Physics 2018-07-06 S. Boettcher , M. Grigni

Submodular functions are an important class of functions in combinatorial optimization which satisfy the natural properties of decreasing marginal costs. The study of these functions has led to strong structural properties with applications…

Multiagent Systems · Computer Science 2009-11-13 Gagan Goel , Pushkar Tripathi , Lei Wang

Monotonicity constraints are powerful regularizers in statistical modelling. They can support fairness in computer-aided decision making and increase plausibility in data-driven scientific models. The seminal min-max (MM) neural network…

Machine Learning · Computer Science 2024-05-28 Christian Igel

Recent works have highlighted scale invariance or symmetry present in the weight space of a typical deep network and the adverse effect it has on the Euclidean gradient based stochastic gradient descent optimization. In this work, we show…

Machine Learning · Computer Science 2015-11-04 Vijay Badrinarayanan , Bamdev Mishra , Roberto Cipolla

Many native structures of proteins accomodate complex topological motifs such as knots, lassos, and other geometrical entanglements. How proteins can fold quickly even in the presence of such topological obstacles is a debated question in…

Soft Condensed Matter · Physics 2020-10-07 Federico Norbiato , Flavio Seno , Antonio Trovato , Marco Baiesi

The problem of designing policies for in-network function computation with minimum energy consumption subject to a latency constraint is considered. The scaling behavior of the energy consumption under the latency constraint is analyzed for…

Networking and Internet Architecture · Computer Science 2016-11-17 Paul Balister , Béla Bollobás , Animashree Anandkumar , Alan Willsky

Recently, we showed that optimization problems, both in infinite as well as in finite dimensions, for continuous variables and soft excluded volume constraints, can display entire isostatic phases where local minima of the cost function are…

Disordered Systems and Neural Networks · Physics 2021-08-27 Silvio Franz , Antonio Sclocchi , Pierfrancesco Urbani

Collective motion of dislocations is governed by the obstacles they encounter. In pure crystals, dislocations form complex structures as they become jammed by their anisotropic shear stress fields. On the other hand, introducing disorder to…

Materials Science · Physics 2020-10-13 Henri Salmenjoki , Lasse Laurson , Mikko J. Alava

As graph data becomes more ubiquitous, the need for robust inferential graph algorithms to operate in these complex data domains is crucial. In many cases of interest, inference is further complicated by the presence of adversarial data…

Machine Learning · Statistics 2022-08-23 Sheyda Peyman , Minh Tang , Vince Lyzinski